John S. Brownstein

John S. Brownstein


Research Focus & Metrics

Academic Career Length

22Years (2005-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 October 2020 in Nature Medicine
Verified
Journal Article
Closed access
PDF file
BRBenjamin Rader
Benjamin Rader
SSSamuel V. Scarpino
Samuel V. Scarpino
ANAnjalika Nande
Anjalika Nande
AHAlison L. Hill
Alison L. Hill
BABen Adlam
Ben Adlam
MKMoritz U. G. Kraemer
Moritz U. G. Kraemer

1 April 2022 in MMWR. Morbidity and Mortality Weekly Report
Verified
Journal Article
Open access
BRBenjamin Rader
Benjamin Rader
AGAutumn Gertz
Autumn Gertz
AIA. Danielle Iuliano
A. Danielle Iuliano
MGMatthew Gilmer
Matthew Gilmer
LWLaura Wronski
Laura Wronski
JBJohn S. Brownstein
John S. Brownstein
This report describes an increase in use of at-home rapid COVID-19 antigen tests between the Delta and Omicron predominant periods during August 2021 to March 2022.

1 March 2021 in The Lancet Digital Health
Verified
Journal Article
Open access
BRBenjamin Rader
Benjamin Rader
LWLaura F White
Laura F White
MBMichael R Burns
Michael R Burns
JCJack Chen
Jack Chen
JBJoseph Brilliant
Joseph Brilliant
JBJohn S. Brownstein
John S. Brownstein
Face masks have become commonplace across the USA because of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic. Although evidence suggests that masks help to curb the spread of the disease, there is little empirical research at the population level. We investigate the association between self-reported mask-wearing, physical distancing, and SARS-CoV-2 transmission in the USA, along with the effect of statewide mandates on mask uptake. Serial cross-sectional surveys were administered via a web platform to randomly surveyed US individuals aged 13 years and older, to query self-reports of face mask-wearing. Survey responses were combined with instantaneous reproductive number (Rt) estimates from two publicly available sources, the outcome of interest. Measures of physical distancing, community demographics, and other potential sources of confounding (from publicly available sources) were also assessed. We fitted multivariate logistic regression models to estimate the association between mask-wearing and community transmission control (Rt<1). Additionally, mask-wearing in 12 states was evaluated 2 weeks before and after statewide mandates. 378 207 individuals responded to the survey between June 3 and July 27, 2020, of which 4186 were excluded for missing data. We observed an increasing trend in reported mask usage across the USA, although uptake varied by geography. A logistic model controlling for physical distancing, population demographics, and other variables found that a 10% increase in self-reported mask-wearing was associated with an increased odds of transmission control (odds ratio 3·53, 95% CI 2·03–6·43). We found that communities with high reported mask-wearing and physical distancing had the highest predicted probability of transmission control. Segmented regression analysis of reported mask-wearing showed no statistically significant change in the slope after mandates were introduced; however, the upward trend in reported mask-wearing was preserved. The widespread reported use of face masks combined with physical distancing increases the odds of SARS-CoV-2 transmission control. Self-reported mask-wearing increased separately from government mask mandates, suggesting that supplemental public health interventions are needed to maximise adoption and help to curb the ongoing epidemic. Flu Lab, Google.org (via the Tides Foundation), National Institutes for Health, National Science Foundation, Morris-Singer Foundation, MOOD, Branco Weiss Fellowship, Ending Pandemics, Centers for Disease Control and Prevention (USA).

31 January 2005 in Ecohealth
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Journal Article
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JBJohn S. Brownstein
John S. Brownstein
THTheodore R. Holford
Theodore R. Holford
DFDurland Fish
Durland Fish

10 April 2025 in Nature Communications
Verified
Journal Article
Open access
PDF file
ALAhyoung Lim
Ahyoung Lim
FSFreya M. Shearer
Freya M. Shearer
KSKara Sewalk
Kara Sewalk
DPDavid M. Pigott
David M. Pigott
JCJoseph Clarke
Joseph Clarke
OBOliver J. Brady
Oliver J. Brady
Arboviruses transmitted mainly by Aedes (Stegomyia) aegypti and Ae. albopictus, including dengue, chikungunya, and Zika viruses, and yellow fever virus in urban settings, pose an escalating global threat. Existing risk maps, often hampered by surveillance biases, may underestimate or misrepresent the true distribution of these diseases and do not incorporate epidemiological similarities despite shared vector species. We address this by generating new global environmental suitability maps for Aedes-borne arboviruses using a multi-disease ecological niche model with a nested surveillance model fit to a dataset of over 21,000 occurrence points. This reveals a convergence in suitability around a common global distribution with recent spread of chikungunya and Zika closely aligning with areas suitable for dengue. We estimate that 5.66 (95% confidence interval 5.64-5.68) billion people live in areas suitable for dengue, chikungunya and Zika and 1.54 (1.53-1.54) billion people for yellow fever. We find large national and subnational differences in surveillance capabilities with higher income more accessible areas more likely to detect, diagnose and report viral diseases, which may have led to overestimation of risk in the United States and Europe. When combined with estimates of uncertainty, these suitability maps can be used by ministries of health to target limited surveillance and intervention resources in new strategies against these emerging threats.

27 September 2005 in Oecologia
Verified
Journal Article
Closed access
PDF file
JBJohn S. Brownstein
John S. Brownstein
DSDavid K. Skelly
David K. Skelly
THTheodore R. Holford
Theodore R. Holford
DFDurland Fish
Durland Fish