Frank L. Lee Bowling

Prof. Dr. Frank L. Lee Bowling

Developmental Biomedicine Research Group, The University of Manchester, Manchester, UK

Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 February 2007 in Diabetes Care
Verified
Journal Article
Closed access
FBFrank L. Lee Bowling
Frank L. Lee Bowling
ESEleanna V. Salgami
Eleanna V. Salgami
ABAndrew J.M. Boulton
Andrew J.M. Boulton

6 December 2010 in Wound Repair and Regeneration
Verified
Journal Article
Closed access
PDF file
FBFrank L. Lee Bowling
Frank L. Lee Bowling
LKLaurie King
Laurie King
JPJames A. Paterson
James A. Paterson
JHJingyi Hu
Jingyi Hu
BLBenjamin A. Lipsky
Benjamin A. Lipsky
ABAndrew J.M. Boulton
Andrew J.M. Boulton

4 June 2012 in Diabetic Medicine
Verified
Journal Article
Open access
PDF file
FBFrank L. Lee Bowling
Frank L. Lee Bowling
CAC. A. Abbott
C. A. Abbott
WHW. E. Harris
W. E. Harris
SAS. Atanasov
S. Atanasov
RMRAYAZ MALIK
RAYAZ MALIK
ABAndrew Boulton
Andrew Boulton
Diabet. Med. 29, 1550–1552 (2012) Aims  To compare the Ipswich Touch Test and the VibraTip with the Neuropathy Disability Score and the vibration perception threshold for detecting the ‘at‐risk’ foot.Methods  We directly compared the Ipswich Touch Test and the VibraTip with both the Neuropathy Disability Score ≥ 6 and the vibration perception threshold ≥ 25 V indicating ‘at‐risk’ feet in 83 individuals.Results  The vibration perception threshold and Neuropathy Disability Score tests exhibited almost perfect agreement with each other (P < 0.001). The VibraTip and Ipswich Touch Test results were identical (P < 0.001). The VibraTip and Ipswich Touch Test results also exhibited almost perfect agreement with the vibration perception threshold (P < 0.001) and the Neuropathy Disability Score (P < 0.001).Conclusions  These two simple and efficient tests are easy to teach, reliable and can be used in any setting, and neither requires an external power source. We conclude that both the VibraTip and the Ipswich Touch Test are reliable and sensitive tests for identifying the ‘high‐risk’ foot.

5 January 2009 in Diabetic Medicine
Verified
Journal Article
Open access
PDF file
FBFrank L. Lee Bowling
Frank L. Lee Bowling
LKL. King
L. King
HFH. Fadavi
H. Fadavi
JPJ. A. Paterson
J. A. Paterson
KPK. Preece
K. Preece
ABA. J. M. Boulton
A. J. M. Boulton
Aims Measurement of wound size can predict healing and provide information to guide treatment. This study assesses a novel optical wound imaging system that creates a three‐dimensional image of the ulcer. Methods Using a new camera‐based digital system and traditional elliptical wound measurements, 36 foot ulcers from 31 patients (aged 44–94 years, median 70 years) were examined during a 12‐week period at two centres. Median diabetes duration was 18 years (range 6–56 years). Seventeen percent had Type 1 diabetes, 93% had peripheral neuropathy and 57% had peripheral artery disease. Twenty‐five were reviewed consecutively, resulting in 76 ulcer examinations. Median ulcer size was 94 mm2, with size ranging from 3.1 to 2195 mm2. Results Pearson, Spearman and Kendall rank coefficients showed a strong correlation (in all cases P < 0.001) between digital measurements of wounds against traditional hand‐measured estimates. Intra‐observer variation of wound length using digital elliptical measurement (DEM) gave a coefficient of variation of < 3.0%. Interobserver variation of wound length using DEM was < 6.5%. Variation from a standard known‐size wound area was < 8.0% across 30 trials. Conclusions This study shows a strong correlation between digital and traditional measurement techniques. The system can be easily deployed in routine clinical practice, providing an objective visual record, allowing remote in‐depth analysis.

29 November 2009 in Current Diabetes Reports
Verified
Journal Article
Closed access
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FBFrank L. Lee Bowling
Frank L. Lee Bowling
EJEdward B. Jude
Edward B. Jude
ABAndrew Boulton
Andrew Boulton

1 January 2009 in Journal of Foot and Ankle Research
Verified
Journal Article
Open access
PDF file
FBFrank L. Lee Bowling
Frank L. Lee Bowling
DSDaryl S Stickings
Daryl S Stickings
VEValerie Edwards‐Jones
Valerie Edwards‐Jones
David ArmstrongDavid Armstrong
David Armstrong
ABAndrew Boulton
Andrew Boulton
Background: The purpose of this study was to assess the level of air contamination with bacteria after surgical hydrodebridement and to determine the effectiveness of hydro surgery on bacterial reduction of a simulated infected wound.Methods: Four porcine samples were scored then infected with a broth culture containing a variety of organisms and incubated at 37°C for 24 hours. The infected samples were then debrided with the hydro surgery tool (Versajet, Smith and Nephew, Largo, Florida, USA). Samples were taken for microbiology, histology and scanning electron microscopy pre‐infection, post infection and post debridement. Air bacterial contamination was evaluated before, during and after debridement by using active and passive methods; for active sampling the SAS‐Super 90 air sampler was used, for passive sampling settle plates were located at set distances around the clinic room.Results: There was no statistically significant reduction in bacterial contamination of the porcine samples post hydrodebridement. Analysis of the passive sampling showed a significant (p < 0.001) increase in microbial counts post hydrodebridement. Levels ranging from 950 colony forming units per meter cubed (CFUs/m3) to 16780 CFUs/m3 were observed with active sampling of the air whilst using hydro surgery equipment compared with a basal count of 582 CFUs/m3. During removal of the wound dressing, a significant increase was observed relative to basal counts (p < 0.05). Microbial load of the air samples was still significantly raised 1 hour post‐therapy.Conclusion: The results suggest a significant increase in bacterial air contamination both by active sampling and passive sampling. We believe that action might be taken to mitigate fallout in the settings in which this technique is used.