Dr. Payam Sadeghi, MD is a physician-scientist and former Fellow at the Dermatology and Plastic Surgery Institute, Cleveland Clinic (Cleveland, Ohio, USA). His research and training have focused on microsurgery, reconstructive plastic surgery, and translational experimental models, with particular emphasis on vascularized composite allotransplantation (VCA) and the role of ischemia–reperfusion injury in complex reconstructive outcomes. During his fellowship, Dr. Sadeghi was actively involved in the Cleveland Clinic Microsurgery Laboratory, where he participated in and supported weekly structured microsurgery training programs at both basic and advanced levels. These programs included microsurgical and super-microsurgical arterial and venous end-to-end and end-to-side anastomosis models, designed for residents, fellows, medical students, and reconstructive surgeons across multiple specialties. His research contributions include innovative projects on ex vivo preservation of amputated limbs and perforator flaps using ex vivo normothermic perfusion systems. He collaborated in designing surgical approaches, implementing novel perfusion strategies, and optimizing perfusion protocols aimed at improving tissue viability and functional outcomes. Dr. Sadeghi’s work supports the growing role of perfusion technologies in advancing the future of plastic and reconstructive surgery through translational research and clinical application.