Thermal therapy is a promising treatment for many patients particularly those with surgery intolerance. It has been used since the early age of humanity. Nowadays, the thermal therapy has proved its efficacy, especially in Oncology. In fact, the tumor ablation using a different modality of heating or cooling presents a therapeutic method to ablate the extra mass and eradicate the malignant it. The administration of the energy is performed in various ways using an energy source. Following the level of the used temperature and the nature of the used heating or cooling source, many modalities have been developed. Hyperthermia uses the lowest temperature among them. Other modalities use an elevated temperature to kill and destroy the tumors. These ablative therapies are Radio Frequency Ablation (RFA), Micro Wave Ablation (MWA), High Intensity Focused Ultrasound (HIFU), LASER Ablation (LA), and Cryoablation(CA). With the purpose of doing a general state of the art of the thermal therapies applied in Oncology and enlightening their advantages and limitations, we reviewed many recent and pertinent published works in different databases. We also investigated the cell destruction mechanism due to temperature. We exposed the recent advances and the limitations of these modalities. However, to improve the quality of the treatment and increase the rate of survival, the research is still investigating these modalities. We discussed the future challenges and perspectives of the thermal therapies. Propositions to overpass the limitations of some techniques were introduced.
To meet the target of carbon neutrality by the year 2050 and decrease the dependence on fossil fuels, renewable energy sources (RESs), specifically wind power, and Electric Vehicles (EVs) have to be massively deployed. Nevertheless, the integration of a large amount of wind power, with an intermittent nature, into the grid and the variability of the load on the demand side require an efficient and reliable energy management system (EMS) for operation, scheduling, maintenance and energy trading in the modern power system. This article proposes a new Energy Management Protocol (EMP) based on the combination of Machine Learning (ML) and Game-Theoretic (GT) algorithms to manage the operation of the charging/discharging of EVs from an energy storage system (ESS) via EV supply equipment (EVSE) when the main source of energy is wind power. The ESS can be linked to the grid to overcome downtimes of wind power production. Case study results of wind power forecasting using an ML algorithm and 10 min wind measurements, combined with a GT optimization model, showed good performance in the forecasting and management of power dispatching between EVs to ensure the efficient and accurate operation of the power system.
Side-channel attacks (SCAs) are powerful techniques used to recover keys from electronic devices by exploiting various physical leakages, such as power, timing, and heat. Although heat is one of the less frequently analyzed channels due to the high noise associated with thermal traces, it poses a significant and growing threat to the security of very large-scale integrated (VLSI) microsystems, particularly system in package (SiP) technologies. Thermal side-channel attacks (TSCAs) exploit temperature variations, risking not only hardware damage from excessive heat dissipation but also enabling the extraction of sensitive data, like cryptographic keys, by observing thermal patterns. This dual threat underscores the need for a synergistic approach to thermal management and security in designing integrated microsystems. In response, this paper presents a novel approach that improves the early detection of abnormal thermal fluctuations in SiP designs, preventing cybercriminals from exploiting such anomalies to extract sensitive information for malicious purposes. Our approach employs a new concept called Thermal Digital Twin (TDT), which integrates two previously separate methods and techniques, resulting in successful outcomes. It combines the gradient direction sensor scan (GDSSCAN) to capture thermal data from the physical field programmable gate array (FPGA), which guarantees rapid thermal scan with a measurement period that could be close to a resolution of C, and a temperature range from −C to C; once the data are transmitted in real time to a Digital Twin created in COMSOL Multiphysics® 6.0 for simulation using the Finite Element Method (FEM), the real time required by the CPU to perform all the necessary calculations can extend to several seconds or minutes. This integration allows for a detailed analysis of thermal transfer within the SiP model of our FPGA. Implementation and simulations demonstrate that the Thermal Digital Twin (TDT) approach could reduce the risks associated with TSCA by a significant percentage, thereby enhancing the security of FPGA systems against thermal threats.
30 March 2020 in IEEE Journal of Selected Topics in Signal Processing
We consider the problem of reliable information propagation in the brain using biologically realistic models of spiking neurons. Biological neurons use action potentials, or spikes, to encode information. Information can be encoded by the rate of asynchronous spikes or by the (precise) timing of synchronous spikes. Reliable propagation of synchronous spikes is well understood in neuroscience and is relatively easy to implement by biologically-realistic models of neurons. However, reliable propagation of rate-modulated asynchronous spikes is poorly understood and remains difficult to implement by those models. In this paper, we formulate how a multi-layered feedforward neural network (mlFNN) comprising biologically-plausible model neurons enables propagation of time-varying asynchronous spikes. Gradient descent algorithm is developed to estimate the connectivity between neurons (i.e., synaptic weights) in mlFNN. Furthermore, we propose an abstract network model to replicate information propagation in mlFNN with substantially less complexity in estimating synaptic weights. The abstract model has a great implication for neuromorphic computing, as it can be implemented in neuromorphic circuits with less complexity, less energy, and more speed. Simulation results demonstrate that (i) the mlFNN with optimal synapses transmits asynchronous spikes reliably, and (ii) the abstract network model reproduces information propagation performed by mlFNN with high accuracy (coding fraction = 0.97 ± 0.02). We anticipate that this study will facilitate the design and implementation of biologically realistic mlFNN in neuromorphic circuits as well as cross-fertilizations between the fields of neuromorphic engineering, computational neuroscience and artificial intelligence.
Densely integrated microarchitectures spanning three-dimensional integrated circuits (3D-ICs), chiplet-based designs, and system-in-package (SiP) assemblies make heat a first-order security concern rather than a mere reliability issue. This review consolidates the landscape of thermal side-channel attacks (TSCAs) on densely integrated microarchitectures: we systematize observation vectors and threat models, clarify core concepts and assumptions, compare the most credible evidence from the past decade, and distill the main classes of defenses across the hardware–software stack. We also explain why hardening against thermal leakage is integral to cyber–physical system (CPS) security and outline the most promising research directions for the field. The strategic relevance of this agenda is reflected in current policy and funding momentum, including initiatives by the United States Department of Homeland Security and the Cybersecurity and Infrastructure Security Agency (DHS/CISA) on operational technology (OT) security, programs by the National Science Foundation (NSF) on CPS, and Canada’s Regional Artificial Intelligence Initiative and Cyber-Physical Resilience Program (RAII, >CAD 35 million), to bridge advanced microelectronics with next-generation cybersecurity. This survey offers a clear, high-level map of the problem space and a focused baseline for future work.