Luis Fonte

Dr. Luis Fonte

Tropical Medicine Institute "Pedro Kourí"
orcid

Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 October 2020 in Frontiers in Immunology
Verified
Journal Article
Open access
PDF file
LFLuis Fonte
Luis Fonte
AAArmando Acosta
Armando Acosta
MSMaria E. Sarmiento
Maria E. Sarmiento
MGMaría Ginori
María Ginori
Gissel García MenéndezGissel García Menéndez
Gissel García Menéndez
NNNorazmi Mohd Nor
Norazmi Mohd Nor
COVID-19 Lethality in Sub-Saharan Africa and Helminth Immune Modulation

4 February 2025 in Microorganisms
Verified
Journal Article
Open access
PDF file
ACAriel Crespo
Ariel Crespo
Yaxsier de ArmasYaxsier de Armas
Yaxsier de Armas
VCVirginia Capó
Virginia Capó
EIEnrique Iglesias
Enrique Iglesias
Jaime Palomares-MarínJaime Palomares-Marín
Jaime Palomares-Marín
HGHÉCTOR RAÚL PÉREZ GÓMEZ
HÉCTOR RAÚL PÉREZ GÓMEZ
Cockroaches serve as mechanical vectors for medically important pathogens, and their presence in hospitals is a common occurrence. This review summarizes the pathogens carried by cockroaches collected in hospitals around the world during the period 2000–2024 and focuses on their antibiotic resistance mechanisms and potential impact on the public health system. The conventional techniques are most used to identify microorganisms and determine antibiotic resistance, but there are few studies that use molecular techniques for bacterial identification and resistance mechanism detection. The species that appear most frequently in the selected articles were Escherichia coli (22 articles) and Pseudomonas aeruginosa (11 articles). Regarding antibiotic resistance, this review describes 79.0% (34/43) of the studies analyzed. E. coli and P. aeruginosa bacteria were found to be resistant to antibiotics in 51.2% and 25.6% of articles, respectively. The identification of pathogens carried by cockroaches collected in hospitals suggests a potential risk of these insects in the transmission of healthcare-associated infections, mainly in developing countries, where this issue is most alarming. The collected data suggest that integrated approaches to cockroach control and infestation management should be put in place based on scientific evidence.

Verified
Journal Article
Open access
PDF file
LFLuis Fonte
Luis Fonte
AAArmando Acosta
Armando Acosta
MSMaria E. Sarmiento
Maria E. Sarmiento
NNNorazmi Mohd Nor
Norazmi Mohd Nor
MGMaría Ginori
María Ginori
Enrique CalderonEnrique Calderon
Enrique Calderon
There is an increasing attention to the emerging health problem represented by the clinical and functional long-term consequences of SARS-CoV-2 infection, referred to as postacute COVID-19 syndrome. Clinical, radiographic, and autopsy findings have shown that a high rate of fibrosis and restriction of lung function are present in patients who have recovered from COVID-19. Patients with active TB, or those who have recovered from it, have fibrotic scarred lungs and, consequently, some degree of impaired respiratory function. Helminth infections trigger predominantly type 2 immune responses and the release of regulatory and fibrogenic cytokines, such as TGF-β. Here, we analyze the possible consequences of the overlapping of pulmonary fibrosis secondary to COVID-19 and tuberculosis in the setting of sub-Saharan Africa, the region of the world with the highest prevalence of helminth infection.

20 March 2023 in Frontiers in Immunology
Verified
Journal Article
Open access
KCKai Ling Chin
Kai Ling Chin
LFLuis Fonte
Luis Fonte
BLBoon Huat Lim
Boon Huat Lim
MSMaria E. Sarmiento
Maria E. Sarmiento
AAArmando Acosta
Armando Acosta
Immunomodulation resulting of helminth infection could be an opportunity for immunization against tuberculosis and mucosal pathogens

29 November 2022 in Children
Verified
Journal Article
Open access
PDF file
LFLuis Fonte
Luis Fonte
MGMaría Ginori
María Ginori
Gissel García MenéndezGissel García Menéndez
Gissel García Menéndez
YBYisel Hernandez Barrios
Yisel Hernandez Barrios
Yaxsier de ArmasYaxsier de Armas
Yaxsier de Armas
Enrique CalderonEnrique Calderon
Enrique Calderon
A myriad of reasons, or a combination of them, have been alluded to in order to explain the lower susceptibility of children to SARS-CoV-2 infection and the development of severe forms of COVID-19. This document explores an additional factor, still little addressed in the medical literature related to the matter: nonspecific resistance to SARS-CoV-2 that could be generated by vaccines administered during childhood. The analysis carried out allows one to conclude that a group of vaccines administered during childhood is associated with a lower incidence and severity of SARS-CoV-2 infection among pediatric ages. Looking from an epidemiological perspective, this conclusion must be taken into consideration in order to ensure greater rationality in the design and implementation of prevention and control actions, including the administration of the COVID-19 vaccine, for these ages.

7 June 2021 in Revista Latinoamericana de Difusión Científica
Verified
Journal Article
Closed access
YBYisel Hernandez Barrios
Yisel Hernandez Barrios
LFLuis Fonte
Luis Fonte
MAMaría del Carmen Zabala Argüelles
María del Carmen Zabala Argüelles
DPDennis Pérez
Dennis Pérez
Coronavirus disease 2019 (COVID-19) is, to date, the health problem with the highest impact in the 21st century. The World Health Organization has recommended several prevention and control measures to deal with this pandemic. In this context, social communication plays a key role. In this article we argue that the potential of communication efforts to close the gaps in the COVID-19 response worldwide won´t be fully accomplished until they do address equity-related issues.