Claus Vinther Nielsen

Prof. Dr. Claus Vinther Nielsen

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Research Focus & Metrics

Academic Career Length

37Years (1990-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 August 2012 in BMC Public Health
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CSChristina Malmose Stapelfeldt
Christina Malmose Stapelfeldt
CJChris Jensen
Chris Jensen
NANiels Trolle Andersen
Niels Trolle Andersen
NFNils Fleten
Nils Fleten
CNClaus Vinther Nielsen
Claus Vinther Nielsen
Previous validation studies of sick leave measures have focused on self-reports. Register-based sick leave data are considered to be valid; however methodological problems may be associated with such data. A Danish national register on sickness benefit (DREAM) has been widely used in sick leave research. On the basis of sick leave records from 3,554 and 2,311 eldercare workers in 14 different workplaces, the aim of this study was to: 1) validate registered sickness benefit data from DREAM against workplace-registered sick leave spells of at least 15 days; 2) validate self-reported sick leave days during one year against workplace-registered sick leave.

1 February 1992 in American Journal of Epidemiology
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LBLars P. A. Brandt
Lars P. A. Brandt
CNClaus Vinther Nielsen
Claus Vinther Nielsen
A case-base study in a population of 214,108 commercial and clerical female workers in Denmark during the period 1983–1985 investigated whether increasing job stress, defined as increasing job demands and decreasing job control, increased the risk of an adverse outcome of pregnancy. Information on the cohort, the outcome of 24,362 pregnancies, was obtained by linkage with nationwide health registers. Six case groups were selected: 1) 2,248 spontaneous abortions, 2) 209 stillbirths or deaths within the first year of life, 3) 661 infants with congenital malformations, 3) 593 preterm deliveries, 4) 587 infants with term low birth weights, 5) 988 infants with light-for-date birth weights, and 6) a random sample of 2,252 pregnancies that constituted the reference group. Information on exposure was obtained by mailed questionnaire. When dichotomized scales on data concerning job demand and control were used, there was an increased relative risk of spontaneous abortion (odds ratio = 1.28, 95% confidence interval (Cl) 1.05–1.57) and term low birth weight (odds ratio = 1.46, 95% Cl 1.05–2.04) for women experiencing high job stress. For the other case groups, the odds ratios were as follows: congenital malformation, 1.23 (95% Cl 0.93–1.63); preterm delivery, 1.03 (95% Cl 0.77–1.39); light-for-date birth weight, 1.08 (95% Cl 0.83–1.40); and stillbirth/death within the first year of life, 1.42 (95% Cl 0.90–2.24). No substantial response bias was found. When occupational titles were used as an exposure matrix, no increased risk was found, except for term low birth weight. Recall bias is one possible explanation. Thus, the results must be interpreted with caution. Am J Epidemiol 1992;135:302–11.

1 May 2015 in Spine
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Journal Article
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NRNanna Rolving
Nanna Rolving
CNClaus Vinther Nielsen
Claus Vinther Nielsen
FCFinn Bjarke Christensen
Finn Bjarke Christensen
RHRandi Holm
Randi Holm
CBCody Eric Bünger
Cody Eric Bünger
LOLisa Gregersen Oestergaard
Lisa Gregersen Oestergaard
A randomized clinical trial including 90 patients. To examine the effect of a preoperative cognitive-behavioral intervention (CBT) for patients undergoing lumbar spinal fusion (LSF) surgery. Few published studies have looked at the potential of rehabilitation to improve outcomes after LSF. Rehabilitation programs using CBT are recommended. Furthermore, initiating interventions preoperatively seems beneficial, but only limited data exist in the field of spine surgery. Patients with degenerative disc disease or spondylolisthesis undergoing LSF were randomized to usual care (control group) or preoperative CBT and usual care (CBT group). Primary outcome was change in Oswestry Disability Index from baseline to 1-year follow-up. Secondary outcomes were catastrophizing, fear avoidance belief, work status, and back and leg pain. At 1-year follow-up, there was no statistically significant difference between the CBT group and the control group in Oswestry Disability Index score (P = 0.082). However, the CBT group had achieved a significant reduction of -15 points (-26; -4) already at 3 months (between group difference P = 0.003), and this reduction was maintained throughout the year. There were no differences between groups at 1-year follow-up with regard to any of the secondary outcomes. Participating in a preoperative CBT intervention in addition to usual care did not produce better outcomes at 1-year follow-up for patients undergoing LSF. Although the reduction in disability was achieved much faster in the CBT group, resulting in a significant difference between groups already 3 months after surgery, it did not translate into a faster return to work. Our findings support the need for further research into the use of targeted rehabilitation interventions among patients with elevated levels of catastrophizing and fear avoidance beliefs. 2.

20 May 2016 in BMC Musculoskeletal Disorders
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Journal Article
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NRNanna Rolving
Nanna Rolving
CNClaus Vinther Nielsen
Claus Vinther Nielsen
FCFinn Bjarke Christensen
Finn Bjarke Christensen
RHRandi Holm
Randi Holm
CBCody Eric Bünger
Cody Eric Bünger
LOLisa Gregersen Oestergaard
Lisa Gregersen Oestergaard
Catastrophic thinking and fear-avoidance belief are negatively influencing severe acute pain following surgery causing delayed ambulation and discharge. We aimed to examine if a preoperative intervention of cognitive-behavioural therapy (CBT) could influence the early postsurgical outcome following lumbar spinal fusion surgery (LSF). Ninety patients undergoing LSF due to degenerative spinal disorders were randomly allocated to either the CBT group or the control group. Both groups received surgery and postoperative rehabilitation. In addition, the CBT group received a preoperative intervention focussed on pain coping using a CBT approach. Primary outcome was back pain during the first week (0–10 scale). Secondary outcomes were mobility, analgesic consumption, and length of hospitalisation. Data were retrieved using self-report questionnaires, assessments made by physical therapists and from medical records. No difference between the groups’ self-reported back pain (p = 0.76) was detected. Independent mobility was reached by a significantly larger number of patients in the CBT group than the control group during the first three postoperative days. Analgesic consumption tended to be lower in the CBT group, whereas length of hospitalisation was unaffected by the CBT intervention. Participation in a preoperative CBT intervention appeared to facilitate mobility in the acute postoperative phase, despite equally high levels of self-reported acute postsurgical pain in the two groups, and a slightly lower intake of rescue analgesics in the CBT group. This may reflect an overall improved ability to cope with pain following participation in the preoperative CBT intervention. The study was approved by the Danish Protection Agency (2011-41-5899) and the Ethics Committee of the Central Denmark Region (M-20110047). The trial was registered in Current Controlled Trials ( ISRCTN42281022 ).

1 November 2014 in The Spine Journal
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Journal Article
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OJOle Kudsk Jensen
Ole Kudsk Jensen
CNClaus Vinther Nielsen
Claus Vinther Nielsen
JSJoan Solgaard Sørensen
Joan Solgaard Sørensen
KSKristian Stengaard-Pedersen
Kristian Stengaard-Pedersen

14 October 2014 in Qualitative Health Research
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CHCharlotte Handberg
Charlotte Handberg
STSally Thorne
Sally Thorne
JMJulie Midtgaard
Julie Midtgaard
CNClaus Vinther Nielsen
Claus Vinther Nielsen
KLKirsten Lomborg
Kirsten Lomborg
The tight bond between grounded theory (GT) and symbolic interactionism (SI) is well known within the qualitative health research field. We aimed to disentangle this connection through critical reflection on the conditions under which it might add value as an underpinning to studies outside the GT tradition. Drawing on an examination of the central tenets of SI, we illustrate with a field study using interpretive description as methodology how SI can be applied as a theoretical lens through which layers of socially constructed meaning can help surface the subjective world of patients. We demonstrate how SI can function as a powerful framework for human health behavior research through its capacity to orient questions, inform design options, and refine analytic directions. We conclude that using SI as a lens can serve as a translation mechanism in our quest to interpret the subjective world underlying patients’ health and illness behavior.