Nikolaos Soldatos

Prof. Dr. Nikolaos Soldatos

1. Department of Periodontics and Dental Hygiene, Board Certified Periodontist-Implant Surgeon, Key Opinion Leader (KOL), MIS Implants Technologies Inc., 18-00 Fair Lawn Ave, Fair Lawn, NJ 07410, USA
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Research Focus & Metrics

Academic Career Length

17Years (2010-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2017
Verified
Journal Article
Closed access
Nikolaos SoldatosNikolaos Soldatos
Nikolaos Soldatos
PSPopi Stylianou
Popi Stylianou
VKVasiliki P Koidou
Vasiliki P Koidou
NANikola Angelov
Nikola Angelov
RYRaymond Yukna
Raymond Yukna
GRGeorgios E Romanos
Georgios E Romanos

1 December 2016 in Journal of Periodontology
Verified
Journal Article
Closed access
NSNima D. Sarmast
Nima D. Sarmast
HWHoward H. Wang
Howard H. Wang
Nikolaos SoldatosNikolaos Soldatos
Nikolaos Soldatos
NANikola Angelov
Nikola Angelov
SDSamuel Dorn
Samuel Dorn
VIVincent J. Iacono
Vincent J. Iacono
Background: Although retrograde peri‐implantitis (RPI) is not a common sequela of dental implant surgery, its prevalence has been reported in the literature to be 0.26%. Incidence of RPI is reported to increase to 7.8% when teeth adjacent to the implant site have a previous history of root canal therapy, and it is correlated with distance between implant and adjacent tooth and/or with time from endodontic treatment of adjacent tooth to implant placement. Minimum 2 mm space between implant and adjacent tooth is needed to decrease incidence of apical RPI, with minimum 4 weeks between completion of endodontic treatment and actual implant placement. The purpose of this study is to compile all available treatment modalities and to provide a decision tree as a general guide for clinicians to aid in diagnosis and treatment of RPI.Methods: Literature search was performed for articles published in English on the topic of RPI. Articles selected were case reports with study populations ranging from 1 to 32 patients. Any case report or clinical trial that attempted to treat or rescue an implant diagnosed with RPI was included.Results: Predominant diagnostic presentation of a lesion was presence of sinus tract at buccal or facial abscess of apical portion of implant, and subsequent periapical radiographs taken demonstrated a radiolucent lesion. On the basis of case reports analyzed, RPI was diagnosed between 1 week and 4 years after implant placement. Twelve of 20 studies reported that RPI lesions were diagnosed within 6 months after implant placement. A step‐by‐step decision tree is provided to allow clinicians to triage and properly manage cases of RPI on the basis of recommendations and successful treatments provided in analyzed case reports. It is divided between symptomatic and asymptomatic implants and adjacent teeth with vital and necrotic pulps.Conclusions: Most common etiology of apical RPI is endodontic infection from neighboring teeth, which was diagnosed within 6 months after implant placement. Most common findings, radiographically and clinically, are lesions around implant apex and sinus tract. A small number of implants did not improve with treatment. Decision tree provides a path to diagnose and treat lesions to facilitate their management. Further studies are needed to focus on histologic data around periapical microbiota to establish specific etiology and differential diagnoses compared with marginal peri‐implantitis and other implant‐related conditions.

1 September 2022 in The Journal of Prosthetic Dentistry
Verified
Journal Article
Closed access
EEErin K. Edmondson
Erin K. Edmondson
PTPedro M. Trejo
Pedro M. Trejo
Nikolaos SoldatosNikolaos Soldatos
Nikolaos Soldatos
RWRobin L. Weltman
Robin L. Weltman

31 January 2010 in Atherosclerosis
Verified
Journal Article
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PDF file
KTKonstantinos Tsioufis
Konstantinos Tsioufis
CTCostas Thomopoulos
Costas Thomopoulos
Nikolaos SoldatosNikolaos Soldatos
Nikolaos Soldatos
DSDimitris Syrseloudis
Dimitris Syrseloudis
AKAlexandros Kasiakogias
Alexandros Kasiakogias
CSChristodoulos Stefanadis
Christodoulos Stefanadis

3 July 2018 in International Journal of Dentistry
Verified
Journal Article
Open access
PDF file
GBGabriella Balli
Gabriella Balli
AIAndreas Ioannou
Andreas Ioannou
CPCharles A. Powell
Charles A. Powell
NANikola Angelov
Nikola Angelov
GRGeorgios E. Romanos
Georgios E. Romanos
Nikolaos SoldatosNikolaos Soldatos
Nikolaos Soldatos
Background. The purpose of this systematic review was to accurately assess the procedural success of ridge preservation technique through the application of strict inclusion and exclusion criteria. Data Sources. A methodical search of PubMed of the US National Library of Medicine and the Cochrane Central Register of Controlled Trials was conducted for applicable articles. Only randomized controlled trials comparing ridge preservation treatment with a nongrafting control, ten-subject minimum sample size, and three or more months of follow-up were included in our study. Types of Studies Reviewed. In a screening between January 1980 and September 2017, articles meeting predetermined criteria were further examined in a qualitative data analysis. A thorough search of the databases provided 1876 articles. Of these records, 174 were assessed for eligibility through the systematic employment of inclusion and exclusion criteria. Results. Two records were appropriate for further data analysis. One study used a mixture of a deproteinized cancellous bovine bone and porcine collagen fibers in a block form (DBB/CF), while the other study used leukocyte-platelet-rich fibrin (L-PRF). The use of DBB/CF reduced the magnitude of vertical bone resorption, yet the study showed high risk of bias. The use of L-PRF reduced the magnitude of both the horizontal and vertical crestal bone resorption; however, the low sample size created wide standard deviations between the test and control groups. Inherent weaknesses were present in both studies. Through methodical analysis of both records, the dissimilarities prevented the conduction of a meta-analysis. Implications of Key Findings. Within the limitations of this systematic review, L-PRF reduced the magnitude of vertical and horizontal bone resorption, which places L-PRF as a potential material of choice for ridge preservation procedures. Conclusions. Within the limitations and weaknesses of both studies, the use of DBB/CF prevented the vertical crestal bone resorption while the L-PRF prevented both the horizontal and vertical crestal bone resorption. More randomized controlled clinical trials are needed to eliminate all the confounding factors, which bias the outcome of ridge preservation techniques.

24 September 2022 in Genes
Verified
Journal Article
Open access
PDF file
Nikolaos SoldatosNikolaos Soldatos
Nikolaos Soldatos
HPHuy Pham
Huy Pham
Walid FakhouriWalid Fakhouri
Walid Fakhouri
BNBinh Ngo
Binh Ngo
PLPanagiotis Lampropoulos
Panagiotis Lampropoulos
RWRobin Weltman
Robin Weltman
(1) Background: Several studies showed a sustained temperature of 47 °C or 50 °C for one minute resulted in vascular stasis and bone resorption with only limited bone regrowth over a 3–4-week healing period. The purpose of the present study was to evaluate the temperature changes (ΔΤ) that occur during the preparation of dental implant osteotomies using MIS® straight drills versus Densah® burs in a clockwise (cutting) drilling protocol. (2) Methods: Two hundred forty (240) osteotomies of two different systems’ drills were prepared at 6 mm depth at 800, 1000, and 1200 revolutions per minute (RPM), in fresh, unembalmed tibiae, obtained by a female cadaver. ΔΤ was calculated by subtracting the baseline temperature on the tibial surface, from the maximum temperature-inside the osteotomy (ΔT = Tmax − Tbase). The variables were evaluated both for their individual and for their synergistic effect on ΔΤ with the use of one-, two-, three- and four-way interactions; (3) Results: An independent and a three-way interaction (drill design, drill width, and RPM) was found in all three RPM for the Densah® burs and at 1000 RPM for the MIS® straight drills. As Densah® burs diameter increased, ΔΤ decreased. The aforementioned pattern was seen only at 1000 RPM for the MIS® straight drills. The usage of drills 20 times more than the implant manufacturers’ recommendation did not significantly affect the ΔΤ. A stereoscopic examination of the specimens confirmed the findings. (4) Conclusions: The independent and synergistic effect of drills’ diameter, design and RPM had a significant effect on ΔΤ in human tibiae, which never exceeded the critical threshold of 47 °C.