Li-Hua Yan

Dr. Li-Hua Yan


Research Focus & Metrics

Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 August 2016 in Cogent Chemistry
Verified
Journal Article
Open access
HWHua Wei
Hua Wei
JZJing-Jing Zhu
Jing-Jing Zhu
XLXiao-Qian Liu
Xiao-Qian Liu
WFWei-Hong Feng
Wei-Hong Feng
ZWZhi-Min Wang
Zhi-Min Wang
LYLi-Hua Yan
Li-Hua Yan
Morus, a plant genus from the family of Moraceae, most plants of which are used as traditional medicines in Asian counties. The root barks of Morus plants are normally called as Sang-Bai-Pi (SBP) in Chinese and used for the treatment of inflammatory and respiratory diseases. Decades of research on phytochemistry of SBP have led to the identification of various compounds, such as Diels–Alder-type adducts, flavonoids, benzofurans, stilbenes, polyhydroxylated alkaloids, etc. These compounds have showed a wide range of bioactive features including anti-inflammatory, anti-oxidative, anti-microbic, etc. This review focus on the bioactive compounds and their pharmacological effects of SBP which will help us fully understand the effective substances of SBP, and pave our way to further explore medicinal uses of SBP and comprehensive utilization of Morus species.

31 March 2015 in Molecules
Verified
Journal Article
Open access
PDF file
SZShan-shan Zhang
Shan-shan Zhang
XLXiao-Qian Liu
Xiao-Qian Liu
LYLi-Hua Yan
Li-Hua Yan
QZQiwei Zhang
Qiwei Zhang
ZWZhiming Wang
Zhiming Wang
ZWZhimin Wang
Zhimin Wang
Armillaria mellea is a traditional Chinese medicinal and edible mushroom. Many cultured products of A. mellea have been used to develop commercial medicines in recent years. The chemical composition and activities of the major bioactive chemical components—polysaccharides—may be different because of differences in the raw materials used. Four polysaccharides (SP, CMP, CFBP and CFMP) were obtained from wild sporophores and cultured products (including mycelia, fermentation broth and fermentation mixture) of A. mellea. Their yields, carbohydrate contents, monosaccharide compositions, FT-IR spectra, NMR spectroscopy and antioxidant activities were investigated. All of the polysaccharides were composed of xylose, glucose and galactose without protein. Glucose was the dominant monosaccharide in SP, CMP and CFMP, whereas galactose was the dominant monosaccharide in CFBP. SP and CMP showed higher scavenging DPPH• and ABTS•+ activities and reducing power among four polysaccharides. The carbohydrate content and corresponding glucose percentage were positive influences on the antioxidant activities, whereas the corresponding xylose and galactose percentage were negative influences. A. mellea polysaccharides are potential natural antioxidants. Polysaccharides from cultured products, especially mycelia, are good substitutes for SP and are also potential sources for both dietary supplements and food industries.

13 August 2015 in Journal of Asian Natural Products Research
Verified
Journal Article
Closed access
HWHua Wei
Hua Wei
XLXiao-Qian Liu
Xiao-Qian Liu
JZJing-Jing Zhu
Jing-Jing Zhu
LGLiang-Liang Gao
Liang-Liang Gao
ZWZhimin Wang
Zhimin Wang
LYLi-Hua Yan
Li-Hua Yan
Phytochemical investigation on the seeds of Caesalpinia decapetala led to the isolation of a new cassane diterpenoid with an unusual O bridge between C-19 and C-20, named phanginin Q (1), together with three known cassane diterpenoids, caesaljapin (2), caesaldekarin A (3), and caesaldekarin B (4). The structure of the new compound was elucidated by spectroscopic methods, including 1H NMR, 13C NMR, HSQC, 1H − 1H COSY, HMBC, NOESY, and HR-ESI-MS.

1 May 2015
Verified
Journal Article
Closed access
HLHao Li
Hao Li
FZFeng-Chun Zhao
Feng-Chun Zhao
XYXian-Da Yuan
Xian-Da Yuan
XLXiao-Qian Liu
Xiao-Qian Liu
LCLiang-Mian Chen
Liang-Mian Chen
ZWzhi-min wang
zhi-min wang

1 April 2013
Verified
Journal Article
Closed access
XLXiao-Chen Li
Xiao-Chen Li
LYLi-Hua Yan
Li-Hua Yan
ZWzhi-min wang
zhi-min wang
QZQi-Wei Zhang
Qi-Wei Zhang
JGJian-Ping Gao
Jian-Ping Gao
GZGui-Feng Zhang
Gui-Feng Zhang