Bisphenols are the most-known endocrine disrupting compounds. Due to the possible migration of these compounds from plastics used as food packaging, the food may become contaminated. During past years, molecularly imprinted polymers (MIPs) were excessively being used as sorbents for bisphenols preconcentration from food samples. This review intended to comprehensively discuss and evaluate the recent applications of MIPs in determination of bisphenols in food samples. The fundamentals of MIPs devoted to preconcentration of bisphenols are outlined. Recent studies were discussed in terms of food sample preparation, determination methods, MIP synthesis, and extraction procedure aspects. The significant aspects of applications of the molecular imprinting polymers in food chemistry are evaluated focusing majorly on literature appeared in the last years.

Solid-phase extraction (SPE) was carefully optimised for preconcentration of 2-4-dimethylaniline (2,4-DMA) and 2,4-dimethylformanilide (DMF) from honey samples. Liquid chromatography with tandem mass spectrometry (LC-MS/MS) was used for the separation and quantification of these analytes. By applying the SPE procedure with 200 mg of OASIS HLB sorbent, the limits of detection achieved in honey samples can be lowered to 0.41 µg·kg⁻¹ for 2,4-DMA and 0.69 µg L⁻¹ for DMF. The proposed method achieves good recoveries (81.1–114%) and precision (RSD 1.07–4.05%, n = 3) for analysed honey sample spiked at two concentration levels 1 µg L⁻¹ and 2 µg L⁻¹. The results demonstrated our method can be applied as a simple way for sample preparation of honey samples for determination of amitraz degradation products. In 1 out of 5 of the analysed Polish honey samples, the DMF residues exceed the maximum residual limits (0.2 mg·kg⁻¹ for total amitraz residues).

Bisphenols are well-known endocrine disruptors that can easily migrate from plastic and can containers to food. Due to the complicated matrix and ultra-low concentrations of bisphenols in food, samples require extensive preparation before instrumental analysis. In this paper, an environmental sensitive microgel was employed as a sorbent for the preconcentration of four bisphenols, bisphenol A (BPA), bisphenol B (BPB), bisphenol E (BPE) and bisphenol F (BPF), from liquid food samples. Liquid chromatography with fluorescence detection (LC-FLD) was used for the quantification of bisphenols. By applying microgel solid-phase extraction procedure, the limits of detections achieved in liquid food samples can be lowered to 0.9 µg·L⁻¹ for BPF and BPA, 2.3 µg·L⁻¹ for BPE and 2.9 µg·L⁻¹ for BPB. Only 5 mg of microgel was sufficient to achieve good recoveries (70.5–109%) with precision (RSD 0.21–5.01%, n = 3) for different analyzed liquid food samples spiked at concentration levels of 50 µg·L⁻¹. In five out of twelve of the analyzed samples (pineapple, mandarin, peach, mushroom and pickles), they were contaminated with BPA, and the determined concentration was in the range of 6.2–22 µg·L⁻¹; however, these results are below the specific migration limit (SML) set for BPA (50 µg·kg⁻¹).