With the unprecedented urbanization processes around the world, cities have become the main areas of political, cultural, and economic creation, but these regions have also caused environmental degradation and even affected public health. Ecological landscape is considered as an important way to mitigate the impact of environmental exposure on urban residents. Therefore, quantifying the quality of urban road landscape and exploring its spatial heterogeneity to obtain basic data on the urban environment and provide ideas for urban residents to improve the environment will be a meaningful preparation for further urban planning. In this study, we proposed a framework to achieve automatic quantifying urban street quality by integrating a mass of street view images based on deep learning and landscape ecology. We conducted a case study in Xiamen Island and mapped a series of spatial distribution for ecological indicators including PLAND, LPI, AI, DIVISION, FRAC_MN, LSI and SHDI. Additionally, we quantified street quality by the entropy weight method. Our results showed the streetscape quality of the roundabout in Xiamen was relatively lower, while the central urban area presented a belt-shaped area with excellent landscape quality. We suggested that managers could build vertical greening on some streets around the Xiamen Island to improve the street quality in order to provide greater well-being for urban residents. In this study, it was found that there were still large uncertainties in the mechanism of environmental impact on human beings. We proposed to strengthen the in-depth understanding of the mechanism of environmental impact on human beings in the process of interaction between environment and human beings, and continue to form general models to enhance the ability of insight into the urban ecosystem.