Low-grade systemic inflammation leads to critical alterations of several tissues and organs that can promote the appearance of non-communicable diseases, a risk that is increased in adults with obesity. Exercise training may counteract low-grade systemic inflammation, but there is a lack of consensus on how cytokines are modulated by training in adults with obesity. This study aimed of examining the effects of exercise training on circulating pro- and anti-inflammatory cytokines in adults with overweight and obesity, and whether exercise-induced fat mass reduction could mediate that effect. The search was conducted on Medline (Pubmed), SPORTDiscus and Web of Science databases from January 1998 to August 2021, using keywords pertaining to inflammation, exercise, and obesity. A total of 27 studies were selected, in which the circulating concentration levels of cytokines were analyzed. Endurance training (ET) decreased circulating CRP, IL-6 and TNF-α levels. TNF-α was reduced after resistance and concurrent training (CT), while IL-10 increased after resistance training (RT). Changes in IL-10 and CRP coincided with fat mass reduction, while decreased TNF-α levels were concomitant with changes in IL-6 and IL-10. Exercise training may reduce systemic low-grade inflammation profile in adults with overweight and obesity.

Aims/hypothesis: We aimed to study the association between the availability of exercise facilities and the likelihood of obesity and type 2 diabetes in the adult population of Madrid, Spain. Methods: We analysed the electronic medical records of all 1,270,512 residents of Madrid aged 40–75 years in 2017. Exercise facility availability was defined as the count of exercise facilities in a 1000 m street network buffer around each residential building entrance. Poisson regression with standard errors clustered at census tract level was used to assess prevalence ratios of exercise facility availability tertiles and obesity and type 2 diabetes. We also examined stratified results by tertiles of area-level socioeconomic status (SES) and sex. Results: People living in areas with lower availability of exercise facilities had a higher prevalence of obesity (prevalence ratio [PR] 1.22 [95% CI 1.20, 1.25]) and diabetes (PR 1.38 [95% CI 1.34, 1.43]). We observed effect modification by area-level SES (p<0.001), with stronger associations for residents living in low-SES areas and no association for residents living in high-SES areas. Associations with type 2 diabetes were stronger among women compared with men, while associations with obesity were similar by sex. Conclusions/interpretation: People living in areas with low availability of exercise facilities had a higher prevalence of obesity and type 2 diabetes, and this association was strongest in low-SES areas and for women. Understanding the potential role of exercise facilities in driving inequities in obesity and type 2 diabetes prevalence may inform interventions to reduce health inequities. Graphical

Article: Effect of eight weeks of upper-body plyometric training during the competitive season on professional female volleyball players - The Journal of Sports Medicine and Physical Fitness 2018 October;58(10):1423-31 - Minerva Medica - Journals

Background: This study assessed the impact of acute caffeine intake on muscular strength, power, and endurance performance between resistance-trained male and female individuals according to load in upper- and lower-body exercises. Methods: Here, 76 resistance-trained individuals (38 females, 38 males) participated in a study comparing caffeine and a placebo. Each received either 3 mg/kg of caffeine or a placebo 60 min before tests measuring muscular strength and power through bench press and back squat exercises at different intensities (25%, 50%, 75%, 90% 1RM). Muscular endurance at 65% 1RM was also assessed by performing reps until reaching task failure. Results: Compared to placebo, caffeine increased mean, peak and time to reach peak velocity and power output (p < 0.01, η_p² = 0.242–0.293) in the muscular strength/power test in males and females. This effect was particularly observed in the back squat exercise at 50%, 75% and 90% 1RM (2.5–8.5%, p < 0.05, g = 1.0–2.4). For muscular endurance, caffeine increased the number of repetitions, mean velocity and power output (p < 0.001, η_p² = 0.177–0.255) in both sexes and exercises (3.0–8.9%, p < 0.05, g = 0.15–0.33). Conclusions: Acute caffeine intake resulted in a similar ergogenic effect on muscular strength, power, and endurance performance in upper- and lower-body exercises for male and female resistance-trained participants.

The aim of this paper was to study the relationship between spike speed and the players’ characteristics, anthropometrics, and strength levels throughout the season for a women’s professional volleyball team. Players from a Spanish first division team performed a battery of tests evaluating anthropometric characteristics, strength performance, and spike speed at the beginning, in the middle, and at the end of one competitive season. The variables were: age; training experience; height; one-hand standing reach height; body mass; body mass index; height of the vertical jump with an approach (spike jump); muscle percentage of arms; 1 repetition maximum (1RM) bench press; 1RM pullover; overhead medicine ball throws for distance using 1, 2, 3, 4, and 5 kg; spike angles; and speed of standing and jump spikes. Results showed that players’ general strength (bench press and pullover) and power parameters (medicine ball throws) increased throughout theseason, while speed of the jump did not improve. The variable that best predicted the jump spike speed at all the three time points in the season was the standing spike speed. The players’ training increased their strength and upper-body power, but these improvements were not transferred to players’ hitting speed ability. Push-pull and throwing exercises were not specific enough to improve the hitting ability of the female senior volleyball players.

To study the association between exercise facility availability and type 2 diabetes incidence and its complications, and to explore effect modification by socioeconomic status (SES) and sex in the Madrid adult population. A multilevel longitudinal design, based on a population-based retrospective cohort including 1,214,281 residents of Madrid (Spain) aged 40-75 years from 2015 to 2018. Outcomes were type 2 diabetes incidence and macrovascular (cardiac ischemia and/or stroke) and microvascular (chronic kidney disease, retinopathy, and/or peripheral vascular disease) complications in those with diabetes at baseline. Exercise facility availability was defined as the count of exercise facilities in a 1000 m street network buffer around each participant's residence. Poisson regression models with robust standard errors were used to estimate the risk ratios (RR). Interactions were explored with SES tertiles and by sex. Residents living in areas with lower exercise facility availability showed higher risk of type 2 diabetes (RR_tertile3vs1 = 1.25, CI95% 1.21-1.30) as well as macrovascular (RR_Tertile3vs1 = 1.09 CI95% 1.00-1.19), and microvascular (RR_Tertile3vs1 = 1.10 CI95% 1.01-1.19) complications. Associations were strongest in low SES areas for type 2 diabetes (RR_{tertile3vs1-LOW-SES} = 1.22, CI95% 1.12-1.32; RR_{tertile3vs1-HIGH-SES} = 0.91, CI95% 0.85-0.98) and microvascular complications (RR_{tertile3vs1-LOW-SES} = 1.12, CI95% 0,94-1,33; RR_{tertile3vs1-HIGH-SES} = 0.88, CI95% 0.73-1.05). Living in areas with lower availability of exercise facilities was associated with a greater risk of type 2 diabetes and its complications. Increasing exercise opportunities, particularly in low SES areas, could help reduce the social gradient of diabetes and its complications.