Daily PM_2.5 (aerosol particles with an aerodynamic diameter of less than 2.5 μm) samples were collected at an urban site in Chengdu, an inland megacity in southwest China, during four 1-month periods in 2011, with each period in a different season. Samples were subject to chemical analysis for various chemical components ranging from major water-soluble ions, organic carbon (OC), element carbon (EC), trace elements to biomass burning tracers, anhydrosugar levoglucosan (LG), and mannosan (MN). Two models, the ISORROPIA II thermodynamic equilibrium model and the positive matrix factorization (PMF) model, were applied to explore the likely chemical forms of ionic constituents and to apportion sources for PM_2.5. Distinctive seasonal patterns of PM_2.5 and associated main chemical components were identified and could be explained by varying emission sources and meteorological conditions. PM_2.5 showed a typical seasonality of waxing in winter and waning in summer, with an annual mean of 119 μg m⁻³. Mineral soil concentrations increased in spring, whereas biomass burning species elevated in autumn and winter. Six major source factors were identified to have contributed to PM_2.5 using the PMF model. These were secondary inorganic aerosols, coal combustion, biomass burning, iron and steel manufacturing, Mo-related industries, and soil dust, and they contributed 37 ± 18, 20 ± 12, 11 ± 10, 11 ± 9, 11 ± 9, and 10 ± 12%, respectively, to PM_2.5 masses on annual average, while exhibiting large seasonal variability. On annual average, the unknown emission sources that were not identified by the PMF model contributed 1 ± 11% to the measured PM_2.5 mass. Various chemical tracers were used for validating PMF performance. Antimony (Sb) was suggested to be a suitable tracer of coal combustion in Chengdu. Results of LG and MN helped constrain the biomass burning sources, with wood burning dominating in winter and agricultural waste burning dominating in autumn. Excessive Fe (Ex-Fe), defined as the excessive portion in measured Fe that cannot be sustained by mineral dust, is corroborated to be a straightforward useful tracer of iron and steel manufacturing pollution. In Chengdu, Mo / Ni mass ratios were persistently higher than unity, and considerably distinct from those usually observed in ambient airs. V / Ni ratios averaged only 0.7. Results revealed that heavy oil fuel combustion should not be a vital anthropogenic source, and additional anthropogenic sources for Mo are yet to be identified. Overall, the emission sources identified in Chengdu could be dominated by local sources located in the vicinity of Sichuan, a result different from those found in Beijing and Shanghai, wherein cross-boundary transport is significant in contributing pronounced PM_2.5. These results provided implications for PM_2.5 control strategies.

Quantifying movement variability is a crucial aspect for clinical and laboratory investigations in several contexts. However, very few studies have assessed, in detail, the intra-subject variability across movements and the inter-subject variability. Muscle synergies are a valuable method that can be used to assess such variability. In this study, we assess, in detail, intra-subject and inter-subject variability in a scenario based on a comprehensive dataset, including multiple repetitions of multi-directional reaching movements. The results show that muscle synergies are a valuable tool for quantifying variability at the muscle level and reveal that intra-subject variability is lower than inter-subject variability in synergy modules and related temporal coefficients, and both intra-subject and inter-subject similarity are higher than random synergy matching, confirming shared underlying control structures. The study deepens the available knowledge on muscle synergy-based motor function assessment and rehabilitation applications, discussing their applicability to real scenarios.

At present, due to the errors of wind power, solar power and various types of load forecasting, the optimal scheduling results of the integrated energy system (IES) will be inaccurate, which will affect the economic and reliable operation of the integrated energy system. In order to solve this problem, a day-ahead and intra-day optimal scheduling model of integrated energy system considering forecasting uncertainty is proposed in this paper, which takes the minimum operation cost of the system as the target, and different processing strategies are adopted for the model. In the day-ahead time scale, according to day-ahead load forecasting, an integrated demand response (IDR) strategy is formulated to adjust the load curve, and an optimal scheduling scheme is obtained. In the intra-day time scale, the predicted value of wind power, solar power and load power are represented by fuzzy parameters to participate in the optimal scheduling of the system, and the output of units is adjusted based on the day-ahead scheduling scheme according to the day-ahead forecasting results. The simulation of specific examples shows that the integrated demand response can effectively adjust the load demand and improve the economy and reliability of the system operation. At the same time, the operation cost of the system is related to the reliability of the accurate prediction of wind power, solar power and load power. Through this model, the optimal scheduling scheme can be determined under an acceptable prediction accuracy and confidence level.