Maísa Santos Fonseca

Dr. Maísa Santos Fonseca


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Verified
Journal Article
Open access
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CFClara Fernandez
Clara Fernandez
ASAna Rita Sokolonski
Ana Rita Sokolonski
MFMaísa Santos Fonseca
Maísa Santos Fonseca
DSDanijela Stanisic
Danijela Stanisic
DADanilo Barral Araújo
Danilo Barral Araújo
LTLjubica Tasic
Ljubica Tasic
Silver nanoparticles (AgNPs) have been successfully applied in several areas due to their significant antimicrobial activity against several microorganisms. In dentistry, AgNP can be applied in disinfection, prophylaxis, and prevention of infections in the oral cavity. In this work, the use of silver nanoparticles in dentistry and associated technological innovations was analyzed. The scientific literature was searched using PubMed and Scopus databases with descriptors related to the use of silver nanoparticles in dentistry, resulting in 90 open-access articles. The search for patents was restricted to the A61K code (International Patent Classification), using the same descriptors, resulting in 206 patents. The results found were ordered by dental specialties and demonstrated the incorporation of AgNPs in different areas of dentistry. In this context, the search for patents reaffirmed the growth of this technology and the dominance of the USA pharmaceutical industry over AgNPs product development. It could be concluded that nanotechnology is a promising area in dentistry with several applications.

29 June 2024 in Heliyon
Verified
Journal Article
Open access
MSMatheus Carmo dos Santos
Matheus Carmo dos Santos
ASAna Clara Cerqueira Silva
Ana Clara Cerqueira Silva
CTCarine dos Reis Teixeira
Carine dos Reis Teixeira
FPFilipe Pinheiro Macedo Prazeres
Filipe Pinheiro Macedo Prazeres
RSRosângela Fernandes dos Santos
Rosângela Fernandes dos Santos
Bruna MachadoBruna Machado
Bruna Machado
A focus on water quality has intensified globally, considering its critical role in sustaining life and ecosystems. Wastewater, reflecting societal development, profoundly impacts public health. Wastewater-based epidemiology (WBE) has emerged as a surveillance tool for detecting outbreaks early, monitoring infectious disease trends, and providing real-time insights, particularly in vulnerable communities. WBE aids in tracking pathogens, including viruses, in sewage, offering a comprehensive understanding of community health and lifestyle habits. With the rise in global COVID-19 cases, WBE has gained prominence, aiding in monitoring SARS-CoV-2 levels worldwide. Despite advancements in water treatment, poorly treated wastewater discharge remains a threat, amplifying the spread of water-, sanitation-, and hygiene (WaSH)-related diseases. WBE, serving as complementary surveillance, is pivotal for monitoring community-level viral infections. However, there is untapped potential for WBE to expand its role in public health surveillance. This review emphasizes the importance of WBE in understanding the link between viral surveillance in wastewater and public health, highlighting the need for its further integration into public health management.

31 January 2022 in Nanomaterials
Verified
Journal Article
Open access
PDF file
MFMaísa Santos Fonseca
Maísa Santos Fonseca
Daniela Méria RodriguesDaniela Méria Rodrigues
Daniela Méria Rodrigues
AAAna Rita Sokolonski Antón
Ana Rita Sokolonski Antón
DSDanijela Stanisic
Danijela Stanisic
LTLuiz Marcelo Tomé
Luiz Marcelo Tomé
RPRicardo Portela
Ricardo Portela
Candida spp. resistant to commercially available antifungals are often isolated from patients with oral candidiasis, a situation that points to the need for the development of new therapies. Thus, we evaluated the activity of Fusarium oxysporum-based silver nanoparticles (AgNPs) on Candida spp. isolated from denture stomatitis lesions. Candida isolates were molecularly identified and submitted to susceptibility assays using AgNPs and commercial fungicides. The interference on biofilm formation and the mechanisms of action of AgNPs on Candida spp. were also investigated. Scanning electron microscopy was used to evaluate the morphology of AgNP-treated Candida. Candida albicans was the most frequent species isolated from denture stomatitis cases. All Candida spp. were susceptible to AgNPs at low concentrations, except Candida parapsilosis. AgNPs caused surface damage, cell disruption, and biofilm formation inhibition. The ergosterol supplementation protected C. albicans against the AgNP action. AgNPs are effective against Candida spp. and can be faced as a promising new therapeutic agent against oral candidiasis.