Silvia Miano

Dr. Silvia Miano

orcid

Research Focus & Metrics

Academic Career Length

27Years (2000-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 November 2015 in European Respiratory Journal
Verified
Journal Article
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AKAthanasios G. Kaditis
Athanasios G. Kaditis
MAMaria Luz Alonso Alvarez
Maria Luz Alonso Alvarez
ABAn Boudewyns
An Boudewyns
EAEmmanouel I. Alexopoulos
Emmanouel I. Alexopoulos
RERefika Ersu
Refika Ersu
SVStijn Verhulst
Stijn Verhulst
This document summarises the conclusions of a European Respiratory Society Task Force on the diagnosis and management of obstructive sleep disordered breathing (SDB) in childhood and refers to children aged 2–18 years. Prospective cohort studies describing the natural history of SDB or randomised, double-blind, placebo-controlled trials regarding its management are scarce. Selected evidence (362 articles) can be consolidated into seven management steps. SDB is suspected when symptoms or abnormalities related to upper airway obstruction are present (step 1). Central nervous or cardiovascular system morbidity, growth failure or enuresis and predictors of SDB persistence in the long-term are recognised (steps 2 and 3), and SDB severity is determined objectively preferably using polysomnography (step 4). Children with an apnoea–hypopnoea index (AHI) >5 episodes·h−1, those with an AHI of 1–5 episodes·h−1and the presence of morbidity or factors predicting SDB persistence, and children with complex conditions (e.g.Down syndrome and Prader–Willi syndrome) all appear to benefit from treatment (step 5). Treatment interventions are usually implemented in a stepwise fashion addressing all abnormalities that predispose to SDB (step 6) with re-evaluation after each intervention to detect residual disease and to determine the need for additional treatment (step 7).

25 March 2011 in Sleep and Breathing
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Journal Article
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MVMaria Pia Villa
Maria Pia Villa
ARAlessandra Rizzoli
Alessandra Rizzoli
SMSilvia Miano
Silvia Miano
CMCaterina Malagola
Caterina Malagola

7 December 2017 in European Respiratory Journal
Verified
Journal Article
Closed access
AKAthanasios G. Kaditis
Athanasios G. Kaditis
MAMaria Luz Alonso Alvarez
Maria Luz Alonso Alvarez
ABAn Boudewyns
An Boudewyns
FAFrancois Abel
Francois Abel
EAEmmanouel I. Alexopoulos
Emmanouel I. Alexopoulos
SVStijn Verhulst
Stijn Verhulst
The present statement was produced by a European Respiratory Society Task Force to summarise the evidence and current practice on the diagnosis and management of obstructive sleep disordered breathing (SDB) in children aged 1–23 months. A systematic literature search was completed and 159 articles were summarised to answer clinically relevant questions. SDB is suspected when symptoms or abnormalities related to upper airway obstruction are identified. Morbidity (pulmonary hypertension, growth delay, behavioural problems) and coexisting conditions (feeding difficulties, recurrent otitis media) may be present. SDB severity is measured objectively, preferably by polysomnography, or alternatively polygraphy or nocturnal oximetry. Children with apparent upper airway obstruction during wakefulness, those with abnormal sleep study in combination with SDB symptoms (e.g.snoring) and/or conditions predisposing to SDB (e.g.mandibular hypoplasia) as well as children with SDB and complex conditions (e.g.Down syndrome, Prader–Willi syndrome) will benefit from treatment. Adenotonsillectomy and continuous positive airway pressure are the most frequently used treatment measures along with interventions targeting specific conditions (e.g.supraglottoplasty for laryngomalacia or nasopharyngeal airway for mandibular hypoplasia). Hence, obstructive SDB in children aged 1–23 months is a multifactorial disorder that requires objective assessment and treatment of all underlying abnormalities that contribute to upper airway obstruction during sleep.

1 December 2007 in Sleep Medicine
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Journal Article
Closed access
SMSilvia Miano
Silvia Miano
OBOliviero Bruni
Oliviero Bruni
Maurizio EliaMaurizio Elia
Maurizio Elia
ATAlessia Trovato
Alessia Trovato
ASArianna Smerieri
Arianna Smerieri
RFRaffaele Ferri
Raffaele Ferri

27 September 2012 in European Respiratory Journal
Verified
Journal Article
Open access
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MVMaria Pia Villa
Maria Pia Villa
MPMaria Chiara Paolino
Maria Chiara Paolino
RCRosa Castaldo
Rosa Castaldo
NVNicola Vanacore
Nicola Vanacore
ARAlessandra Rizzoli
Alessandra Rizzoli
MMMarilisa Montesano
Marilisa Montesano
Overnight polysomnography (PSG) is an expensive procedure which can only be used in a minority of cases, although it remains the gold standard for the diagnosis of sleep disordered breathing (SDB). The objective of this study was to develop a simple, PSG-validated tool to screen SDB, thus reducing the use of PSG.For every participant we performed PSG and a sleep clinical record was completed. The sleep clinical record consists of three items: physical examination, subjective symptoms and clinical history. The clinical history analyses behavioural and cognitive problems. All three items were used to create a sleep clinical score (SCS).We studied 279 children, mean±sdage 6.1±3.1 years, 63.8% male; 27.2% with primary snoring and 72.8% with obstructive sleep apnoea (OSA) syndrome. The SCS was higher in the OSA syndrome group compared to the primary snoring group (8.1±9.6versus0.4±0.3, p<0.005), correlated with apnoea/hypopnoea index (p=0.001) and had a sensitivity of 96.05%. Positive and negative likelihood ratios were 2.91 and 0.06, respectively.SCS may effectively be used to screen patients as candidates for PSG study for suspected OSA syndrome, and to enable those with a mild form of SDB to receive early treatment.

1 January 2005 in Sleep Medicine
Verified
Journal Article
Closed access
RFRaffaele Ferri
Raffaele Ferri
OBOliviero Bruni
Oliviero Bruni
SMSilvia Miano
Silvia Miano
MTMario G. Terzano
Mario G. Terzano