PM_2.5 pollution in China is becoming increasingly severe, threatening public health. The major goal of this study is to evaluate the mortality rate attributed to PM_2.5 pollution and design pollution mitigation schemes in a southern district of China through a two-objective optimization model. The mortality rate is estimated by health effect evaluation model. Subjected to limited data information, it is assumed that the meta-analysis method, through summarizing and combining the research results on the same subject, was suitable to estimate the percentage of deaths caused by PM_2.5 pollution. The critical parameters, such as the total number of deaths and the background concentration of PM_2.5, were obtained through on-site survey, data collection, literature search, policy analysis, and expert consultation. The equations for estimating the number of deaths caused by PM_2.5 pollution were established by incorporating the relationship coefficient of exposure to reaction, calculated residual PM_2.5 concentration of affected region, and statistical total base number of deaths into a general framework. To balance the cost from air quality improvement and human health risks, a two-objective optimization model was developed. The first objective is to minimize the mortality rate attributable to PM_2.5 pollution, and the second objective is to minimize the total system cost over three periods. The optimization results demonstrated that the combination of weights assigned to the two objectives significantly influenced the model output. For example, a high weight value assigned to minimizing the number of deaths results in the increased use of treatment techniques with higher efficiencies and a dramatic decrease in pollutant concentrations. In contrast, a model weighted more toward minimizing economic loss may lead to an increase in the death toll due to exposure to higher air pollution levels. The effective application of this model in the Nanshan District of Shenzhen City, China, is expected to serve as a basis for similar work in other parts of the world in the future.

In the past, the research on models related to urban land-use change and prediction was greatly complicated by the high precision of models. When planning some garden cities, we should explore a more applicable, specific, and effective macro approach than the community-level one. In this study, a model consisting of spatial autoregressive (SAR), cellular automata (CA), and Markov chains is constructed. One It can well-consider the spatial autocorrelation and integrate the advantages of CA into a geographical simulation to find the driving forces behind the expansion of a garden city. This framework has been applied to the urban planning and development of Chengdu, China. The research results show that the application of the SAR model shows the development trend in the southeast region and the needs to optimize the central region and protect the western region as an ecological reserve. The descriptive statistics and the spatial autocorrelation of the residuals are reliable. The influence of spatial variables from strong to weak is distance to water, slope, population density, GDP, distance to main roads, distance to railways, and distance to the center of the county (district). Taking 2005 as the initial year, the land-use situation in 2015 was simulated and compared with the actual land-use situation. It seems that the Kappa coefficient of the construction-land simulation is 0.7634, with high accuracy. Therefore, the land use in 2025 and 2035 is further simulated, which provides a reference for garden cities to formulate a reasonable urban space development strategy.