Alexandre Perez

Dr. Alexandre Perez

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Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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19 August 2022 in Diagnostics
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Journal Article
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APAlexandre Perez
Alexandre Perez
VLVincent Lenoir
Vincent Lenoir
Tommaso LombardiTommaso Lombardi
Tommaso Lombardi
Dentigerous cyst is an odontogenic developmental cyst arising from the pericoronal tissue of an impacted tooth, and that may exhibit various radiological aspects. The aim of this article is to present four cases of histologically confirmed mandibular dentigerous cysts to highlight diverse radiological presentations: one of classical appearance (well-limited unilocular radiolucent lesion surrounding the crown) and three which have shown radiological peculiarities (one cyst displacing the adjacent tooth, with bone but no root resorption, one cyst presenting hallmarks of infection and one multilocular cyst with thin septa). Such radiologic diversity may, on occasion, suggest a clinical aggressive lesion such as an odontogenic keratocyst or ameloblastoma. The diagnosis of dentigerous cyst requires a thorough evaluation of the clinical presentation and accurate radiological studies.

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PSPaolo Scolozzi
Paolo Scolozzi
FMFrancesco Michelini
Francesco Michelini
CCClaude Crottaz
Claude Crottaz
APAlexandre Perez
Alexandre Perez
Traditional dental implant surgery has been challenged by the phenomenal progression in computer-assisted surgery (CAS) that we have been witnessing in recent years. Among the computer-aided technologies, computer-aided design and computer-aided manufacturing (CAD/CAM) techniques represent by far the most attractive and accepted alternatives over their dynamic counterpart, navigational assistance. Based on many years of experience, we have determined that CAD/CAM technology for guiding dental implant surgery is valuable for rehabilitation of the anterior maxillary region and the management of complete or severe partial edentulism. The technology also guarantees the 3D parallelism of implants. The purpose of the present report is to describe indications for use of CAD/CAM dental implant guided surgery. We analyzed the clinical and radiological data of thirteen consecutive edentulous patients treated using CAD/CAM techniques. All of the patients had stable cosmetic results with a high rate of patient satisfaction at the final follow-up examination. No intra- and/or postoperative complications were encountered during any of the steps of the procedure. The application of CAD/CAM techniques produced successful outcomes in the patients presented in this series.

2 August 2024 in Applied Sciences
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VCValerio Cimini
Valerio Cimini
APAlexandre Perez
Alexandre Perez
Tommaso LombardiTommaso Lombardi
Tommaso Lombardi
RFRoberto Di Felice
Roberto Di Felice
Background: Osseointegration is fundamental to achieving successful implant therapy in dentistry. However, the heat generated during implant placement emerges as a critical factor predisposing to implant failure. Objective: This study aimed to analyze the different factors related to heat generation during implant placement, offering insights to clinicians in their daily clinical practice. Methods: Utilizing the PubMed, Web of Science, and Embase databases, we conducted an electronic search for articles published between January 2013 and December 2023. The analysis focused on several factors including bone type, drill shape, drill speed, drill material, drilling force, osteotomy depth, drill load, drilling technique (intermittent or continuous), presence of a surgical guide, irrigation methods, drill wear, and preparation tools available. Results: Initially, 2525 records were identified. After applying the inclusion and exclusion criteria and full-text assessment, 93 articles were included in this scoping review. Additionally, some articles published before 2013 were incorporated in the bibliography to ensure completeness of the review. Conclusions: Heat generation during implant placement arises from a complex interplay of multiple factors. While irrigation and bone hardness appear to be crucial determinants of heat generation during the osteotomy phase, the involvement of other factors remains less clear. Further studies are needed to better understand the precise contribution of these factors towards increasing temperature at the implant site.

5 January 2022 in Oral
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EDEdouard Di Donna
Edouard Di Donna
LKLoïc Mahé Keller
Loïc Mahé Keller
ANAnnika Neri
Annika Neri
APAlexandre Perez
Alexandre Perez
Tommaso LombardiTommaso Lombardi
Tommaso Lombardi
Supernumerary teeth may be encountered as an incidental finding on a radiograph. When impacted, they may be associated with clinical signs related to different problems such as failure of eruption, teeth displacement, root resorption or cystic lesions. They may occur in primary and permanent dentition, in both the maxilla and mandible and can be single or multiple in patients with syndromes. Mesiodens is the most commonly impacted tooth and appears between the central maxillary incisors in pediatric ages. Supernumerary teeth distal to the third molar are rare, usually impacted and referred to as a distomolar. A 46-year-old male consulted with the main complaint of pain on the left side of the maxilla. A panoramic radiograph revealed a right impacted maxillary fourth molar located posterior to the third molar associated with a pericoronal radiolucency. The supernumerary tooth was removed surgically under local anesthesia and the pericoronal lesion enucleated. Histopathological examination was consistent with the diagnosis of a dentigerous cyst associated with an impacted distomolar. Healing was uneventful, and the patients remained asymptomatic. The occurrence of an impacted maxillary distomolar is rare and even rarer the association with a dentigerous cyst.

23 April 2023 in Clinical Case Reports
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Journal Article
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APAlexandre Perez
Alexandre Perez
BLBenjamin Lazzarotto
Benjamin Lazzarotto
LMLaurine Marger
Laurine Marger
Stephane DurualStephane Durual
Stephane Durual
This report documents the clinical and histological outcome of 3D‐printed calcium phosphate blocks placed in two‐stage procedures to successfully rehabilitate atrophic alveolar ridges. This approach yielded a functionally favorable result. Histological evaluations were performed after healing periods of 6 months and showed ongoing bone regeneration and sprouting capillaries.

18 November 2025 in Applied Sciences
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APAlexandre Perez
Alexandre Perez
Tommaso LombardiTommaso Lombardi
Tommaso Lombardi
Advances in digital dental technologies have transformed implant therapy from analog, stepwise processes into advanced, data-driven workflows spanning diagnosis, planning, surgery, and prosthetic delivery. Contemporary digital implantology integrates multiple techniques, tools, and multimodal datasets into comprehensive diagnostic models and treatment workflows, enhancing implant placement accuracy, procedural efficiency, patient experience, and interdisciplinary coordination. However, integration remains constrained by fragmented datasets, diverse software platforms, and parallel surgical and prosthetic streams. These interfaces often require manual user intervention to convert, process, and align data, thereby increasing the risk of data loss, artifact generation, misalignment, and error accumulation, which may impact implant and prosthetic restorative outcomes. Similarly, implant and prosthetic planning steps continue to rely on subjective, non-standardized user input, requiring advanced experience and training. This narrative review synthesizes current evidence and technical developments in digital implant dentistry based on literature searches in PubMed, Scopus, and Web of Science, with emphasis on publications from 2010 onward, prioritizing systematic reviews, randomized clinical trials, and technical reports focusing on key technological innovations. It presents the current state of the art in digital implantology and identifies major workflow interfaces that constrain seamless, end-to-end integration. This part I summarizes contemporary tools and approaches in digital implant technology. In contrast, Part II of this series will address the emerging roles of artificial intelligence and robotics in overcoming these limitations and advancing toward fully integrated digital implant prosthodontic workflows. Overall, current digital implant workflows are clinically reliable and are equivalent to, or often superior to, conventional approaches in terms of efficiency and accuracy. Nevertheless, their full potential remains limited by persistent software, data, and process interface barriers.