David Lee Nelson

Dr. David Lee Nelson

Department of Pharmacy, Universidade Federal dos Vales do Jequitinhonha e Mucuri—UFVJM, R. da Glória, 187, Diamantina 39100-000, Brazil
orcid

Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 March 2023 in Food Technology and Biotechnology
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Journal Article
Open access
GCGabriela Aguiar Campolina
Gabriela Aguiar Campolina
MCMaria Das Graças Cardoso
Maria Das Graças Cardoso
ACAlex Rodrigues Silva Caetano
Alex Rodrigues Silva Caetano
DNDavid Lee Nelson
David Lee Nelson
EREduardo Mendes Mendes Ramos
Eduardo Mendes Mendes Ramos
The meat and meat product industry has evolved according to the needs of the market. Consumers are increasingly seeking quality in food. Thus, the concern regarding the excessive use of additives such as preservatives and antioxidants has driven research towards natural, healthy and safe substitutes. Essential oils and plant extracts have been shown to be a good option for resolving this problem. They are completely natural with biological activity, which mainly includes prevention of oxidation and the proliferation of microorganisms, thus arousing the interest of the industry and consumers. This review will present studies published in the last five years regarding the potential of essential oils and plant extracts to act as preservatives and antioxidants in meat and meat products. The forms of application, innovations in the area, alternatives to the incorporation of essential oils and extracts in meat products, effects caused in food, and limitations of applications will be detailed and discussed.

1 June 2011 in Revista Brasileira de Fruticultura
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ALAnnete de Jesus Boari Lima
Annete de Jesus Boari Lima
ACAngelita Duarte Corrêa
Angelita Duarte Corrêa
ADAna Maria Dantas-Barros
Ana Maria Dantas-Barros
DNDavid Lee Nelson
David Lee Nelson
AAAna Carolina Lourenço Amorim
Ana Carolina Lourenço Amorim
The aim of this work was to determine the sugar, organic acid and mineral compositions of the whole fruit and fractions (skin, pulp and seed) of the Paulista (Plinia cauliflora) and Sabará (Plinia jaboticaba) jabuticaba tree genotypes, as well as the oil compositions of their skin and seeds. High levels of sugar, especially fructose, followed by glucose and sucrose, were encountered in the fruit. In the Paulista genotype, higher levels of total and reducing sugars were found in the pulp and skin, which was not observed when comparing the whole fruit of both genotypes. Five organic acids were found in the whole fruit and in the fractions of the two jabuticaba genotypes in quantitative order: citric acid > succinic acid > malic acid > oxalic acid > acetic acid. Potassium was the most abundant mineral found. This fruit was also shown to be rich in magnesium, phosphorus, calcium and copper. The seed oil had nearly the same constitution as the oil extracted from the skin in both genotypes and the major compounds were an unidentified phytosterol, palmitic, linoleic and oleic acids, and squalene.

25 May 2020 in Biomass Conversion and Biorefinery
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Sandro Luiz dos SantosSandro Luiz dos Santos
Sandro Luiz dos Santos
MFMilton S. de Freitas
Milton S. de Freitas
WSWallans T. P. dos Santos
Wallans T. P. dos Santos
DNDavid Lee Nelson
David Lee Nelson
MFMaria Betânia de Freitas-Marques
Maria Betânia de Freitas-Marques
ABAdriano C. Moraes Baroni
Adriano C. Moraes Baroni

30 January 2022 in Molecules
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Sandro Luiz dos SantosSandro Luiz dos Santos
Sandro Luiz dos Santos
ARAdeline C. Pereira Rocha
Adeline C. Pereira Rocha
DNDavid Lee Nelson
David Lee Nelson
MFMilton S. de Freitas
Milton S. de Freitas
AMAntônio A. P. Fulgêncio Mestre
Antônio A. P. Fulgêncio Mestre
RRRegiane D. Fernandes Rios
Regiane D. Fernandes Rios
SiO2-SO3H, with a surface area of 115 m2·g−1, pore volumes of 0.38 cm3·g−1 and 1.32 mmol H+/g, was used as a transesterification catalyst. Triglycerides of waste cooking oil reacted with methanol in refluxing toluene to yield mixtures of diglycerides, monoglycerides and fatty acid methyl esters (FAMEs) in the presence of 20% (w/w) catalyst/oil using the hydrophilic sulfonated silica (SiO2-SO3H) catalyst alone or with the addition of 10% (w/w) co-catalyst/oil [(Bun4N)(BF4) or Aliquat 336]. The addition of the ammonium salts to the catalyst lead to a decrease in the amounts of diglycerides in the products, but the concentrations of monoglycerides increased. Mixtures of (Bun4N)(BF4)/catalyst were superior to catalyst alone or Aliquat 336/catalyst for promoting the production of mixtures with high concentrations of FAMEs. The same experiments were repeated using DMSO as the solvent. The use of the more polar solvent resulted in excellent conversion of the triglycerides to FAME esters with all three-catalyst media. A simplified mechanism is presented to account for the experimental results.

1 April 2007 in Transactions of the Royal Society of Tropical Medicine and Hygiene
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LMLiliani Salum Alves Moreira
Liliani Salum Alves Moreira
DPDorila Piló-Veloso
Dorila Piló-Veloso
RMRômulo Teixeira de Mello
Rômulo Teixeira de Mello
PCPaulo Marcos Zech Coelho
Paulo Marcos Zech Coelho
DNDavid Lee Nelson
David Lee Nelson
The schistosomicidal activities of seven 2-(alkylamino)-1-phenyl-1-ethanethiosulfuric acids (1a–g) (R = propyl, isopropyl, butyl, isobutyl, t-butyl, sec-butyl, cyclohexyl, respectively) were determined in female Swiss mice infected with Schistosoma mansoni. The compounds were administered in a single oral dose of 800 mg/kg to groups of 15 mice infected with 50 cercariae each. All the compounds were found to be active, a high animal mortality being observed with 1e. These compounds have a high specificity against female worms (64–100% reduction vs. 33–61% reduction in male worms). The test was repeated, a 400-mg/kg sub-dose of 1f also being tested, and similar results were observed. A 94% reduction in the number of female worms was observed when compound 1c was administered in a single 800-mg/kg dose to animals infected with 80 cercariae. Finally, the test was repeated with single 800 mg/kg oral doses of compounds 1e (highly purified) and 1f and a 400-mg/kg sub-dose of 1c. The toxicity of 1e was confirmed, while the animals that received 1c and 1f presented reductions in the worm loads corresponding to 45.9% (male worms) and 84.8% (female worms) for 1c and 50.4% (male worms) and 94.2% (female worms) for 1f.

6 August 2020 in Journal of the Science of Food and Agriculture
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MMMaísa Lamounier Magalhães
Maísa Lamounier Magalhães
RSRaimundo Vicente de Sousa
Raimundo Vicente de Sousa
JMJosé Rafael Miranda
José Rafael Miranda
IKIsaac Konig
Isaac Konig
FWFlademir Wouters
Flademir Wouters
MCMaria Das Graças Cardoso
Maria Das Graças Cardoso