The study of medicinal plants is important, as they are the natural reserve of potent biologically active compounds. With wide use in traditional medicine and the inclusion of several species (as parts and as a whole plant) in pharmacopeia, species from the genus Salvia L. are known for the broad spectrum of their biological activities. Studies suggest that these plants possess antioxidant, anti-inflammatory, antinociceptive, anticancer, antimicrobial, antidiabetic, antiangiogenic, hepatoprotective, cognitive and memory-enhancing effects. Phenolic acids, terpenoids and flavonoids are important phytochemicals, which are primarily responsible for the medicinal activity of Salvia L. This review collects and summarizes currently available data on the pharmacological properties of sage, outlining its principal physiologically active components, and it explores the molecular mechanism of their biological activity. Particular attention was given to the species commonly found in Kazakhstan, especially to Salvia trautvetteri Regel, which is native to this country.

The cosmetics industry is one of the fastest growing markets in terms of searching for new ingredients. Recently, there has been a growing interest in products made during fermentation, which are being introduced into cosmetics with increasing frequency, creating a market that emphasizes the positive image of healthy, environmentally friendly components with a positive effect on skin. Scientists mainly focus on examining biological activity as well as the impact on changes in the production of bioactive ingredients in various plant species undergoing fermentation. The studies show that bioferments have scientifically proven anti-aging and anti-inflammatory effects, among other skin benefits. Due to the increasing emphasis on environmental protection, ecofriendly compounds are being sought. This group includes surfactants, which are also obtained by fermentation. Plant-based and microbial biosurfactants, due to their multifunctional properties, such as detergency, emulsifying, foaming, moisturizing, and antibacterial activity, can replace chemical surfactants in many skincare formulations. This review focuses especially on elucidating the importance of the bioferments and biosurfactants and their potential in the cosmetic industry.

There are numerous publications demonstrating that plant polyphenols can reduce oxidative stress and inflammatory processes in the brain. In the present study we have investigated the neuroprotective effect of plant extract isolated from the roots of L. gmelinii since it contains a rich source of polyphenols and other biologically active compounds. We have applied an oxidative and inflammatory model induced by NMDA, H₂O₂, and TNF-α in human primary neurons and astrocytes, and mouse cerebral endothelial cell (CECs) line in vitro. The levels of ROS generation, NADPH oxidase activation, P-selectin expression, and activity of ERK1/2 were evaluated by quantitative immunofluorescence analysis, confocal microscopy, and MAPK assay. In vivo, sensorimotor functions in rats with middle cerebral artery occlusion (MCAO) were assessed. In neurons NMDA induced overproduction of ROS, in astrocytes TNF-α initiated ROS generation, NADPH oxidase activation, and phosphorylation of ERK1/2. In CECs, the exposure by TNF-α induced oxidative stress and triggered the accumulation of P-selectin on the surface of the cells. In turn, pre-treatment of the cells with the extract of L. gmelinii suppressed oxidative stress in all cell types and pro-inflammatory responses in astrocytes and CECs. In vivo, the treatment with L. gmelinii extract improved motor activity in rats with MCAO.

Increase productivity and quality of wheat by improving its genotype – one of the main problems of agriculture. Currently, using conventional methods of breeding and genetic research, such as mutagenesis, backcrossing selection and distant hybridization can increase the effectiveness of producing genetically improved crop forms. The fertility rate of soft wheat hybrids of wild species with T. timopheevi depends on the direction of crosses and genotype of varieties. Wild species as the parent component favorably affect a high percentage of tying grains.

The article is devoted to issues of amines production from nitro compounds. The processes of catalytic reduction of aromatic nitrocompounds by hydrogen to amines have practically superseded all other methods for the production of aromatic amines in large-tonnage plants. Aromatic mono-, di- and polyamines, due to their high reactivity, are widely used in the production of various compounds (photochemicals, fuel stabilizers and additives lubricating oils, in the paint and varnish industry, for painting natural and synthetic fibers). Authors compare methods of nitro compounds reduction and show different variants of apparature design. The article also describes the results of enlarged laboratory examinations of the deposited catalysts synthesized by authors in reactions of p-phenylenediamine, p-amino-diethylaniline, o- and p-aminophenols production. By using relatively small amounts of catalysts (0.48-0.6 g of catalyst by hydrogenating 50 g of an aromatic nitro compound) were obtained high amine yields of 90-98.7%.