Chitosan is a biopolymer that is found in nature and is produced from chitin deacetylation. Chitosan has been studied thoroughly for multiple applications with an interdisciplinary approach. Antifungal antibacterial activities, mucoadhesion, non-toxicity, biodegradability, and biocompatibility are some of the unique characteristics of chitosan-based biomaterials. Moreover, chitosan is the only widely-used natural polysaccharide, and it is possible to chemically modify it for different applications and functions. In various fields, chitosan composite and compound manufacturing has acquired much interest in developing several promising products. Chitosan and its derivatives have gained attention universally in biomedical and pharmaceutical industries as a result of their desired characteristics. In the present mini-review, novel methods for preparing chitosan-containing materials for dental and implant engineering applications along with challenges and future perspectives are discussed.
1 February 2018 in Journal of Composites for Construction
This paper presents test results carried out to investigate the mechanical properties of E-glass fiber-reinforced polymer (E-GFRP) bars with four different diameters (6, 8, 10, and 14 mm) after these bars were subjected to sequential exposure to ultraviolet (UV) radiation and water vapor condensation for different time periods (1,000, 2,000, and 3,000 h) and elevated temperatures (15–300°C). The mechanical properties of the GFRP bars were evaluated with tensile, flexural, short beam (shear), and low-cyclic fatigue tests conducted on 150 specimens after exposure conditions. A scanning electron microscope (SEM) was used to investigate the degradation mechanism of the bars subjected to UV radiation and water vapor condensation. The results showed that, generally, with increases in exposure time and temperature the mechanical properties of the bars decreased. UV radiation and water vapor condensation conditions did not show a significant effect on direct tensile tests, in comparison with flexural and short beam tests. Furthermore, GFRP bars lost up to 45% of their tensile strength at elevated temperatures.
Several experimental and numerical studies have been conducted to address the structural performance of FRP-reinforced/strengthened concrete structures under and after exposure to elevated temperatures. The present paper reviews over 100 research studies focused on the structural responses of different FRP-reinforced/strengthened concrete structures after exposure to elevated temperatures, ranging from ambient temperatures to flame. Different structural systems were considered, including FRP laminate bonded to concrete, FRP-reinforced concrete, FRP-wrapped concrete, and concrete-filled FRP tubes. According to the reported data, it is generally accepted that, in the case of insignificant resin in the post curing process, as the temperature increases, the ultimate strength, bond strength, and structure stiffness reduce, especially when the glass transition temperature Tg of the resin is approached and exceeded. However, in the case of post curing, resin appears to preserve its mechanical properties at high temperatures, which results in the appropriate structural performance of FRP-reinforced/strengthened members at high temperatures that are below the resin decomposition temperature Td. Given the research gaps, recommendations for future studies have been presented. The discussions, findings, and comparisons presented in this review paper will help designers and researchers to better understand the performance of concrete structures that are reinforced/strengthened with FRPs under elevated temperatures and consider appropriate approaches when designing such structures.
The second cause of death in the world has been reported to be cancer, and it has been on the rise in recent years. As a result of the difficulties of cancer detection and its treatment, the survival rate of patients is unclear. The early detection of cancer is an important issue for its therapy. Cancer detection based on biomarkers may effectively enhance the early detection and subsequent treatment. Nanomaterial-based nanobiosensors for cancer biomarkers are excellent tools for the molecular detection and diagnosis of disease. This review reports the latest advancement and attainment in applying nanoparticles to the detection of cancer biomarkers. In this paper, the recent advances in the application of common nanomaterials like graphene, carbon nanotubes, Au, Ag, Pt, and Fe 3 O 4 together with newly emerged nanoparticles such as quantum dots, upconversion nanoparticles, inorganics (ZnO, MoS 2 ), and metal–organic frameworks for the diagnosis of biomarkers related to lung, prostate, breast, and colon cancer are highlighted. Finally, the challenges, outlook, and closing remarks are given.