A facile and efficient visible-light-driven method has been developed to construct sulfoxides via oxidative coupling of aryldiazo sulfones with thiols using the O2 in air as the oxidant. This reaction could be performed at room temperature under catalyst- and additive-free conditions. The present methodology offers a mild and environmentally benign approach to obtain a library of sulfoxides in good yields with favorable functional group tolerance.
A mild and facile visible-light-mediated strategy has been proposed for the synthesis of 3-acyl quinoxalin-2(1H)-ones through acridine red catalyzed aerobic oxidative decarboxylative acylation of α-oxo-carboxylic acids with quinoxalin-2(1H)-ones at room temperature in air. Various 3-acyl quinoxalin-2(1H)-ones could be efficiently obtained in good yields with excellent functional group compatibility.
A novel visible-light-induced and Rose Bengal catalyzed strategy has been developed for the synthesis of α-ketoamides via decarboxylative acylations of isocyanides with α-oxocarboxylic acids and water under mild conditions.
A new and facile visible-light-enabled method for the synthesis of α-azidoketones has been developed via oxyazidation of alkenes with TMSN3 in air at room temperature. A series of α-azidoketones could be easily and efficiently obtained in moderate to excellent yields via cascade C–N and CO bond formation by simply using low-toxic and inexpensive Rose Bengal (1 mol%) and PhSeSePh (5 mol%) as co-catalysts.