Amirreza Ghaznavi

Mr. Amirreza Ghaznavi


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 June 2024 in Advanced Materials Technologies
Verified
Journal Article
Open access
AGAmirreza Ghaznavi
Amirreza Ghaznavi
JXJie Xu
Jie Xu
CLChristine U. Lee
Christine U. Lee
SHSeth Hara
Seth Hara
A 3D‐printed array of hollow microneedles (HMNs) is designed and fabricated using a high‐resolution stereolithography 3D printer and assembled with a 3D‐printed reservoir that incorporates a Luer lock mechanism, ensuring standard and secure connection to syringes. The proof‐of‐concept needle designs consist of half‐eccentric and concentric conical tip shapes, each arrayed with two different interspacing values. After the geometrical features of the devices are characterized, the devices are tested ex vivo in porcine skin to evaluate the impact of tip shape and interspacing on the depth of penetration and the efficacy of the devices in delivering fluids (such as tattoo ink) into the dermis. Overall, the 3D‐printed HMNs can deliver fluids into the target layer of skin. Refinement of the design is ongoing with the ultimate aim to provide alternatives for intradermal drug delivery and diagnostic imaging, such as superficial lymphography.

26 January 2022 in Micromachines
Verified
Journal Article
Open access
PDF file
AGAmirreza Ghaznavi
Amirreza Ghaznavi
Yang LinYang Lin
Yang Lin
MDMark Douvidzon
Mark Douvidzon
ASAdam Szmelter
Adam Szmelter
ARAlannah Rodrigues
Alannah Rodrigues
JXJie Xu
Jie Xu
We report a microfluidic droplet generator which can produce single and compound droplets using a 3D axisymmetric co-flow structure. The design considered for the fabrication of the device integrated a user-friendly and cost-effective 3D printing process. To verify the performance of the device, single and compound emulsions of deionized water and mineral oil were generated and their features such as size, generation frequency, and emulsion structures were successfully characterized. In addition, the generation of bio emulsions such as alginate and collagen aqueous droplets in mineral oil was demonstrated in this study. Overall, the monolithic 3D printed axisymmetric droplet generator could offer any user an accessible and easy-to-utilize device for the generation of single and compound emulsions.

30 June 2023 in Micromachines
Verified
Journal Article
Open access
PDF file
AGAmirreza Ghaznavi
Amirreza Ghaznavi
JXJie Xu
Jie Xu
SHSeth Hara
Seth Hara
Three-dimensional printing technology has been implemented in microfluidic mold fabrication due to its freedom of design, speed, and low-cost fabrication. To facilitate mold fabrication processes and avoid the complexities of the soft lithography technique, we offer a non-sacrificial approach to fabricate microscale features along with mesoscale features using Stereolithography (SLA) printers to assemble a modular microfluidic mold. This helps with addressing an existing limitation with fabricating complex and time-consuming micro/mesoscale devices. The process flow, optimization of print time and feature resolution, alignments of modular devices, and the advantages and limitations with the offered technique are discussed in this paper.

16 July 2021
Verified
Preprint
Open access
AGAmirreza Ghaznavi
Amirreza Ghaznavi
JXJie Xu
Jie Xu
Yang LinYang Lin
Yang Lin
TCTal Carmon
Tal Carmon
LDLev Deych
Lev Deych
LYLan Yang
Lan Yang
Droplet microfluidics has been attracting interests of users in diverse fields of study such as cosmetics, pharmaceutical, and food industries due to its versatility in applications. This vast interest in droplet based microfluidics is rooted in its specific capabilities to encapsulate biological and chemical reagents inside tiny amount of fluids, offering precise control over