Lone Holst

Dr. Lone Holst

orcid

Research Focus & Metrics

Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 July 2009 in The Journal of Alternative and Complementary Medicine
Verified
Journal Article
Closed access
LHLone Holst
Lone Holst
DWDavid Wright
David Wright
SHSvein Haavik
Svein Haavik
HNHedvig Nordeng
Hedvig Nordeng
Background: The physiologic changes that occur during pregnancy can lead to a variety of conditions that can usually be self-treated. There are no licensed medicines for conditions such as morning sickness or insomnia in pregnancy, and evidence from Western countries suggests that patients often resort to using herbal medicines. Research on the health behaviors of pregnant women in the United Kingdom with respect to herbal remedies has not been undertaken. Objective: The objective of this study is to describe the use and the user of herbal remedies during pregnancy and to study the sources of information about herbs used. Design: The study design was a survey among expectant mothers more than 20 weeks pregnant presenting at an antenatal clinic. Setting: The setting was an antenatal clinic and antenatal ultrasound department at Norfolk and Norwich University Hospital. One thousand and thirty-seven (1037) questionnaires were handed out between November 2007 and February 2008. Results: Five hundred and seventy-eight (578) questionnaires were returned (55.7%). Three hundred and thirty-four (334) of the 578 respondents (57.8%) reported using herbal remedies during pregnancy with a mean of 1.2 remedies per woman (median: 1, range: 0–10). The most commonly used remedies were ginger, cranberry, and raspberry leaf. The most probable user had been pregnant before and had a university degree. “Family and friends” were the most frequently cited source of information about herbal remedies during pregnancy, and more than 75% of the users reportedly did not tell their doctor or midwife about the use. Conclusions: A large percentage of the women in the study used herbal remedies during pregnancy—many of them without informing their doctor or midwife. Doctors or midwives should ask pregnant women if they use herbal remedies during pregnancy. Health care personnel should be open to discuss the use of herbal remedies during pregnancy and be able to give balanced information as the use is so widespread.

28 February 2017 in BMC Pregnancy and Childbirth
Verified
Journal Article
Open access
PDF file
KHKristine Heitmann
Kristine Heitmann
HNHedvig Nordeng
Hedvig Nordeng
GHGro C. Havnen
Gro C. Havnen
ASAnja Solheimsnes
Anja Solheimsnes
LHLone Holst
Lone Holst
Though nausea and vomiting is very common during pregnancy, no studies have investigated the impact of this condition on the women’s daily lives in a Scandinavian population. The aim of this study was to describe the burden of nausea and vomiting during pregnancy (NVP) on global quality of life, daily life functioning and willingness to become pregnant again according to the severity of NVP symptoms. This study is a cross-sectional population-based study conducted in Norway. Pregnant women and mothers with children <1 year of age with current or prior NVP were eligible to participate. Data were collected through an anonymous on-line questionnaire accessible from November 10th, 2014 to January 31st, 2015. Severity of NVP was measured using the 24-h Pregnancy Unique Quantification of Emesis Scale (PUQE). Associations between severity of NVP, daily life functioning and willingness to become pregnant again were tested using chi-square tests. Associations with global quality of life measured in terms of the Quality of Life Scale (QOLS) were estimated using generalized linear models and reported as unstandardized regression coefficients (β) with 95% confidence intervals (CI). 712 women with NVP were included in the study. NVP was significantly associated with several characteristics, including daily life functioning, quality of life and willingness to become pregnant again. The negative impact was greater the more severe the symptoms were, although considerable adverse effects were also seen among women with mild and moderate NVP symptoms. Over one fourth of the women with severe NVP considered terminating the pregnancy due to NVP, and three in four considered not to get pregnant again. Severity of NVP remained significantly associated with reduced global quality of life when adjusting for maternal characteristics and illnesses with β (95% CI) = −10.9 (−16.9, −4.9) for severe versus mild NVP. NVP as measured by PUQE had a major impact on various aspects of the women’s lives, including global quality of life and willingness to become pregnant again.

15 January 2019 in BMC Public Health
Verified
Journal Article
Open access
PDF file
MWMarit Waaseth
Marit Waaseth
AAAbdifatah Adan
Abdifatah Adan
IRIngrid L. Røen
Ingrid L. Røen
KEKaroline Eriksen
Karoline Eriksen
TSTijana Stanojevic
Tijana Stanojevic
HNHedvig Nordeng
Hedvig Nordeng
Antibiotic resistance is a global health threat. Public knowledge is considered a prerequisite for appropriate use of antibiotics and limited spread of antibiotic resistance. Our aim was to examine the level of knowledge of antibiotics and antibiotic resistance among Norwegian pharmacy customers, and to assess to which degree beliefs, attitudes and sociodemographic factors are associated with this knowledge. A questionnaire based, cross-sectional study was conducted among pharmacy customers in three Norwegian cities. The questionnaire covered 1) knowledge of antibiotics (13 statements) and antibiotic resistance (10 statements), 2) the general beliefs about medicines questionnaire (BMQ general) (three subdomains, four statements each), 3) attitudes toward antibiotic use (four statements), and 4) sociodemographic factors, life style and health. High knowledge level was defined as > 66% of maximum score. Factors associated with knowledge of antibiotics and antibiotic resistance were investigated through univariate and multiple linear regression. Hierarchical model regression was used to estimate a population average knowledge score weighted for age, gender and level of education. Among 877 participants, 57% had high knowledge of antibiotics in general and 71% had high knowledge of antibiotic resistance. More than 90% knew that bacteria can become resistant against antibiotics and that unnecessary use of antibiotics can make them less effective. Simultaneously, more than 30% erroneously stated that antibiotics are effective against viruses, colds or influenza. Factors positively associated with antibiotic knowledge were health professional background, high education level, and a positive view on the value of medications in general. Male gender, a less restrictive attitude toward antibiotic use, and young age were negatively associated with antibiotic knowledge. The mean overall antibiotic knowledge score was relatively high (15.6 out of maximum 23 with estimated weighted population score at 14.8). Despite a high level of knowledge of antibiotics and antibiotic resistance among Norwegian pharmacy customers, there are obvious knowledge gaps. We suggest that action is taken to increase the knowledge level, and particularly target people in vocational, male dominated occupations outside the health service, and primary/secondary school curricula.

1 February 2011 in Midwifery
Verified
Journal Article
Closed access
LHLone Holst
Lone Holst
DWDavid Wright
David Wright
SHSvein Haavik
Svein Haavik
HNHedvig Nordeng
Hedvig Nordeng

31 January 2008 in Pharmacoepidemiology and Drug Safety
Verified
Journal Article
Closed access
PDF file
LHLone Holst
Lone Holst
HNHedvig Nordeng
Hedvig Nordeng
SHSvein Haavik
Svein Haavik

17 June 2012 in European Journal of Clinical Pharmacology
Verified
Journal Article
Closed access
PDF file
KHKristine Heitmann
Kristine Heitmann
HNHedvig Nordeng
Hedvig Nordeng
LHLone Holst
Lone Holst