Purpose: The social vulnerability index (SVI), developed by the Centers for Disease Control and Prevention, is a novel composite measure encompassing multiple variables that correspond to key social determinants of health. The objective of this review was to investigate innovative applications of the SVI to oncology research and to employ the framework of the cancer care continuum to elucidate further research opportunities.Methods: A systematic search for relevant articles was performed in five databases from inception to 13 May 2022. Included studies applied the SVI to analyze outcomes in cancer patients. Study characteristics, patent populations, data sources, and outcomes were extracted from each article. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.Results: In total, 31 studies were included. Along the cancer care continuum, five applied the SVI to examine geographic disparities in potentially cancer-causing exposures; seven in cancer diagnosis; fourteen in cancer treatment; nine in treatment recovery; one in survivorship care; and two in end-of-life care. Fifteen examined disparities in mortality.Conclusion: In highlighting place-based disparities in patient outcomes, the SVI represents a promising tool for future oncology research. As a reliable geocoded dataset, the SVI may inform the development and implementation of targeted interventions to prevent cancer morbidity and mortality at the neighborhood level.

Gastrointestinal immune-related adverse events (GI irAEs) are common manifestations of immune checkpoint inhibitor (ICI) toxicity. We present a comprehensive systematic review of the incidence, management, and clinical course of irAEs across the entire GI system, including the luminal GI tract, liver, and pancreas. MEDLINE, Embase, Web of Science Core Collection, and Cochrane Library were used to conduct this review. All studies pertaining to GI irAEs were included. Both abstracts and full manuscripts were eligible if they included human subjects and were written in the English language. Articles not available in English, animal studies, or research not specific to GI toxicity of immunotherapy were excluded. We excluded certain article types depending on whether stronger evidence was available in the literature for a specific toxicity, for example, if prospective studies were available on a topic, retrospective studies and case reports were excluded. We extracted a final 166 articles for our review and followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for data reporting. Risk of bias tools were not used to evaluate the extracted studies given the narrative nature of this manuscript, but each study was critically appraised by the manuscript writer. We detail the incidence, presentation, evaluation, management, and outcomes of the various GI toxicities that may arise with ICI therapy. Specifically, we discuss the characteristics of upper GI toxicity (esophagitis and gastroenteritis), lower GI toxicity (colitis), hepatobiliary inflammation, pancreatitis, and rarer forms of GI toxicity. We hope this review serves as a useful and accessible clinical tool that helps physicians familiarize themselves with the nuances of gastrointestinal/hepatic/pancreatic ICI toxicity diagnosis and management.

This literature review examines the use of interventional treatments for pain management in pediatric cancer patients. While interventional procedures may be effective in cancer pain management, these procedures are infrequently employed in pediatric cohorts. This underutilization of interventional procedures may be supported by a deficit in randomized, controlled studies and literature regarding their role in pediatric cancer populations. Particularly because literature on the efficacy of interventional treatments in adult populations may not directly translate to pediatric populations, more research about the role of interventional procedures in managing pediatric cancer pain is necessary for a strengthened understanding of pediatric cancer pain treatment.

PolicyMap is an online geographic information system (GIS) mapping tool that aggregates many types of data for users to create maps and reports for research, grant applications, health policy, market surveys, and other applications. Currently, it incorporates over 37,000 data indicators from more than 150 public and private agencies to power the platform. Although the data are amassed from many different sources, they are cleaned and normalized to reduce redundancy and maintain integrity. In addition to federal, state, and local governments, PolicyMap is used by educational institutions, foundations, nonprofit organizations, and health care systems to help make impactful decisions.

Background: Librarians play an important role on systematic review teams because of their expertise in information organization, database searching, and records management. Many systematic review training opportunities exist, but not all are tailored to the needs of librarians. The Medical Library Association, along with a workgroup of experts on systematic reviews and review services, developed a Systematic Review Services Specialization (SRSS) that was launched in 2022. One of the required courses in the specialization was developed by the authors, who set out to build a value-added curriculum that would provide essential searching skills for librarians working in evidence synthesis domains. Case Presentation: The authors present a case report on creating a framework for developing a new course in the Medical Library Association's Systematic Review Services Specialization. The objectives of the course were intended to align with six systematic review competencies for librarians developed and published by a group of health science librarians from the University of Michigan in 2017, which include 1) conducting a reference interview, 2) performing preliminary searches, 3) selecting appropriate resources to search, 4) building an extensive, comprehensive, and documented search strategy, 5) peer reviewing search strategies, and 6) reporting search methods. With these objectives in mind, the instructors created four separate modules and an activity. Conclusion: Systematic review skills for librarians are essential to many health science library jobs since librarians are considered important collaborators within systematic review teams. Through eleven cohorts of the course held over 2022-2024, the authors constructed and delivered a comprehensive curriculum.