The ubiquity of microplastics in the environment has caused great influence to ecosystems and seriously threatened human health. To better understand the variation in microplastics in different seasons in an inland freshwater environment and determine the sources of microplastic pollution and its migration features, this study investigated the characteristics of microplastic pollution during dry (April) and wet (July) seasons in surface water of the Manas River Basin, China. The size, color, shape, area distribution and compound composition of microplastics were studied. Moreover, the risk of microplastic contamination was explored based on risk assessment models. The results demonstrated that the degree of pollution caused by microplastic abundance was minor in this study area. The average abundance of microplastics in April (17 ± 4 items/L) was higher than that in July (14 ± 2 items/L). The range in the abundance of microplastics in April and July were 22 ± 5-14 ± 3 items/L and 19 ± 2-10 ± 1 items/L, respectively. Highly hazardous polymers such as Polyvinyl chloride (PVC) and Polycarbonate (PC) have a significant impact on the results of the evaluation of the presence of microplastics. This study is an important reference for understanding the characteristics of the seasonal variation in microplastics in inland freshwater environments and has practical significance, as it will allow relevant agencies to accurately assess the pollution level of microplastics in different seasons. It is of practical significance to understand the sources and sinks of microplastics in inland freshwater environment.

In recent years, antibiotics have become widely used in animal breeding. The application of antibiotics in livestock may lead to the presence of antibiotic residues in animal‐derived foods, especially meat, that may pose a threat to human health. In this study, 26 common antibiotics (eight sulfonamides, nine fluoroquinolones, four tetracyclines, and five macrolides) were screened in 88 meat samples (cattle muscles and sheep muscles, kidneys, and livers) obtained from southern Xinjiang. The antibiotics were screened via the clean‐up step based on solid‐phase extraction and determined through ultraperformance liquid chromatography–tandem mass spectrometry. Moreover, their risk to human health was analyzed. Overall, 16 antibiotics were detected with a total detection rate of 95.46%. The percentage of noncompliant samples was 28.41% with an exceedance maximum residue limit of 1.14%. The illegal use rate of the antibiotic norfloxacin was 27.27%. The estimated daily exposure doses of all compounds in adults were <102.218 ng/kg bw/day even after applying the worst‐case scenario approach. This result demonstrated that the antibiotic residues in the tested samples imposed negligible harm to people's health and had an acceptable level of food safety risk. However, the high detection frequencies found in this work indicated that the risk of antibiotic residues could not be ignored given the cumulative risk of antibiotics, particularly the emergence of bacterial resistance, to the human body. The need for effective strategies and publicity for the judicious use of antibiotics to safeguard residents’ health is immediate.