In recent years, the need to protect and conserve biodiversity has become more critical than ever before, as a prerequisite for both sustainable development and the very survival of the human species. This has made it a priority for the scientific community to develop technological solutions that provide data and information for monitoring, directly or indirectly, biodiversity and the drivers of change. A new era of satellite earth observation upgrades the potential of Remote Sensing (RS) to support, at relatively low cost, but with high accuracy the extraction of information over large areas, at regular intervals, and over extended periods of time. Also, the recent development of the Earth Observation Data Cubes (EODC) framework facilitates EO data management and information extraction, enabling the mapping and monitoring of temporal and spatial patterns on the Earth’s surface. This submission presents the ELBIOS EODC, specifically developed to support the biodiversity management and conservation over Greece. Based on the Open Data Cube (ODC) framework, it exploits multi-spectral optical Copernicus Sentinel-2 data and provides a series of Satellite Earth Observation (SEO) biodiversity products and spectral indices nationwide.