Dae Jean Jo

Prof. Dr. Dae Jean Jo

orcid

Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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7 November 2017 in Toxins
Verified
Journal Article
Open access
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BSByung-Kwan Seo
Byung-Kwan Seo
KHKyungsun Han
Kyungsun Han
OKOJin Kwon
OJin Kwon
DJDae Jean Jo
Dae Jean Jo
JLJun-Hwan Lee
Jun-Hwan Lee
Bee venom acupuncture (BVA) is an effective treatment for chronic low back pain (CLBP) through the pharmacological effects of bee venom and the simultaneous stimulation of acupoints. However, evidence of its efficacy and safety in humans remains unclear. Using a double-blind, randomized study, 54 patients with non-specific CLBP were assigned to the BVA and sham groups. All participants underwent six sessions of real or sham BVA for 3 weeks, in addition to administration of 180 mg of loxonin per day. The primary outcome, that is, “bothersomeness” derived from back pain, was assessed using the visual analog scale. Secondary outcomes included pain intensity, dysfunction related to back pain (Oswestry Disability Index), quality of life (EuroQol 5-Dimension), and depressive mood (Beck’s depression inventory). Outcomes were evaluated every week during the treatment period and followed up at weeks 4, 8, and 12. After 3 weeks of the treatment, significant improvements were observed in the bothersomeness, pain intensity, and functional status in the BVA group compared with the sham group. Although minimal adverse events were observed in both groups, subsequent recovery was achieved without treatment. Consequently, our results suggest that it can be used along with conventional pharmacological therapies for the treatment of CLBP.

30 September 2023 in Neurospine
Verified
Journal Article
Open access
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BLByung-Jou Lee
Byung-Jou Lee
SBSungSoo Bae
SungSoo Bae
HCHo Yong Choi
Ho Yong Choi
JPJin Hoon Park
Jin Hoon Park
SHSeung-Jae Hyun
Seung-Jae Hyun
K(Korean Spinal Deformity Society (Ksds)
Korean Spinal Deformity Society (Ksds)
Proximal junction kyphosis (PJK) is a common imaging finding after long-level fusion, and proximal junctional failure (PJF) is an aggravated form of the progressive disease spectrum of PJK. This includes vertebral fracture of upper instrumented vertebra (UIV) or UIV+1, instability between UIV and UIV+1, neurological deterioration requiring surgery. Many studies have reported on PJK and PJF after long segment instrumentation for adult spinal deformity (ASD). In particular, for spine deformity surgeons, risk factors and prevention strategies of PJK and PJF are very important to minimize reoperation. Therefore, this review aims to help reduce the occurrence of PJK and PJF by updating the latest contents of PJK and PJF by 2023, focusing on the risk factors and prevention strategies of PJK and PJF. We conducted a search on multiple database for articles published until February 2023 using the search keywords “proximal junctional kyphosis,” “proximal junctional failure,” “proximal junctional disease,” and “adult spinal deformity.” Finally, 103 papers were included in this study. Numerous factors have been suggested as potential risks for the development of PJK and PJF, including a high body mass index, inadequate postoperative sagittal balance and overcorrection, advanced age, pelvic instrumentation, and osteoporosis. Recently, with the increasing elderly population, sarcopenia has been emphasized. The quality and quantity of muscle in the surgical site have been suggested as new risk factor. Therefore, spine surgeon should understand the pathophysiology of PJK and PJF, as well as individual risk factors, in order to develop appropriate prevention strategies for each patient.

30 June 2023 in Neurospine
Verified
Journal Article
Open access
PDF file
YCYongjae Cho
Yongjae Cho
DJDae Jean Jo
Dae Jean Jo
SHSeung-Jae Hyun
Seung-Jae Hyun
JPJin Hoon Park
Jin Hoon Park
NYNa Rae Yang
Na Rae Yang
In the last 20 years, sagittal alignment and balance of the spine have become one of the most important issues in the field of spine surgery. Recent studies emphasize that sagittal balance and alignment are more important for health-related quality of life. The understanding of normal and abnormal sagittal alignment of the spine is necessary for the diagnosis and appropriate treatment of adult spinal deformity (ASD), and we will discuss the currently used classification of ASD, the parameters of sagittal alignment that are essential for the diagnosis of spinal deformity, compensatory actions to maintain sagittal balance, and the relationship between sagittal alignment and clinical symptoms. Furthermore, we will also discuss the recently introduced Global Alignment and Proportion scores. The Korean Spinal Deformity Society is publishing a series of review articles on spinal deformities to help spine surgeons better understand spinal deformities.

21 April 2014 in Trials
Verified
Journal Article
Open access
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BSByung-Kwan Seo
Byung-Kwan Seo
JLJun-Hwan Lee
Jun-Hwan Lee
PKPil-Kun Kim
Pil-Kun Kim
YBYong-Hyeon Baek
Yong-Hyeon Baek
DJDae Jean Jo
Dae Jean Jo
SLSanghun Lee
Sanghun Lee
Chronic neck pain (CNP) is a common painful medical condition with a significant socioeconomic impact. In spite of widespread usage, the effectiveness and safety of combined treatments between conventional and complementary alternative medical treatment modalities has not been fully established in a rigorous randomized clinical trial (RCT). This pilot study will provide the clinical evidence to evaluate the feasibility and refine the protocol for a full-scale RCT on combined treatment of bee venom acupuncture (BVA) and non-steroidal anti-inflammatory drugs (NSAIDs) in patients with CNP.

14 January 2013 in Trials
Verified
Journal Article
Open access
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BSByung-Kwan Seo
Byung-Kwan Seo
JLJun-Hwan Lee
Jun-Hwan Lee
WSWon-Suk Sung
Won-Suk Sung
ESEun-Mo Song
Eun-Mo Song
DJDae Jean Jo
Dae Jean Jo
Chronic non-specific low back pain is the most common medical problem for which patients seek complementary and alternative medical treatment, including bee venom acupuncture. However, the effectiveness and safety of such treatments have not been fully established by randomized clinical trials. The aim of this study is to determine whether bee venom acupuncture is effective for improving pain intensity, functional status and quality of life of patients with chronic non-specific low back pain.

30 September 2023 in Neurospine
Verified
Journal Article
Open access
PDF file
SSSeung-Ho Seo
Seung-Ho Seo
SHSeung-Jae Hyun
Seung-Jae Hyun
JLJae-Koo Lee
Jae-Koo Lee
YCYong Jae Cho
Yong Jae Cho
DJDae Jean Jo
Dae Jean Jo
OSOn Behalf Of The Korean Spinal Deformity Society
On Behalf Of The Korean Spinal Deformity Society
Adolescent idiopathic scoliosis (AIS) affects approximately 2% of adolescents across all ethnicities. The objectives of surgery for AIS are to halt curve progression, correct the deformity in 3 dimensions, and preserve as many mobile spinal segments as possible, avoiding junctional complications. Despite ongoing development in algorithms and classification systems for the surgical treatment of AIS, there is still considerable debate about selecting the appropriate fusion level. In this study, we review the literature on fusion selection and present current concepts regarding the lower instrumented vertebra in the selection of the fusion level for AIS surgery.