In this work, extraction of flavonoids from peanut shells has been studied in the presence of ultrasound and the results are compared with Soxhlet and heat reflux extraction for establishing the process intensification benefits. The process optimization for understanding the effects of operating parameters, such as ethanol concentration, particle size, solvent to solid ratio, extraction temperature, ultrasonic power and ultrasonic frequency, on the extraction of flavonoids has been investigated in details. The highest extraction yield (9.263 mg/g) of flavonoids was achieved in 80 min at optimum operating parameters of particle size of 0.285 mm, solvent to solid ratio of 40 ml/g, extraction temperature of 55 °C, ultrasonic power of 120 W and ultrasonic frequency of 45 kHz with 70% ethanol as the solvent. Two kinetic models (i.e. phenomenological model and Peleg's model) have been introduced to describe the extraction kinetic of flavonoids by fitting experimental data and predict kinetic parameters. Good performance with slight loss of goodness of fit of two models was found by comparing their coefficient of determination (R2), root mean square error (RMSE) and/or mean percentage error (MPE) values. This work would provide the reduction of degradation and the economic evaluation for the extraction processes of flavonoids from peanut shells, as well as give a better explanation for the mechanism of ultrasound.

• Multi-frequency ultrasound was firstly applied to extract TPC and TMA from eggplant. • UD Combined with PLS was firstly used to determine the optimal extraction conditions. • Impact of ultrasound in different frequencies and powers on TPC and TMA were studied. • The sound extraction efficiency of TFU was superior to non-ultrasound, SFU and DFU. • The application prospect of multi-frequency ultrasound in extraction field is great.

Berries, as the best dietary sources for human health, are rich in anthocyanins, vitamins, fiber, polyphenols, essential amino acids, and other ingredients. Anthocyanins are one of the most important bioactive components in berries. The attractive color of berries is attributed to the fact that berries contain different kinds of anthocyanins. Increasing research activity has indicated that anthocyanins in berries show various biological activities, including protecting vision; antioxidant, anti-inflammatory and anti-tumor qualities; inhibition of lipid peroxidation; anti-cardiovascular disease properties; control of hypoglycemic conditions; and other activities. Hence, berries have high nutritional and medicinal values. The recognized absorption, metabolism, and biological activities of anthocyanins have promoted their research in different directions. Hence, it is necessary to systematically review the research progress and future prospects of anthocyanins to promote a better understanding of anthocyanins. The absorption, metabolism, and biological activities of anthocyanins from berries were reviewed in this paper. The findings of this study provide an important reference for basic research, product development and utilization of berries’ anthocyanins in food, cosmetics, and drugs.

To understand the effect of coupling parameters between two ultrasonic waves on acoustic cavitation, in this work, Keller-Miksis equation was introduced to built a bubble dynamics model that was used to describe the dynamic evolution of bubble and to discuss the effect of dual-frequency coupling parameters, such as frequency difference f (5 ∼ 280 kHz), phase difference φ (0 ∼ 7π/4 rad), and power allocation ratio β (0 ∼ 9), on acoustic cavitation in the presence of two ultrasonic waves irradiation. The enhancement and attenuation effect of cavitation have also been analyzed in detail by comparing the different dual-frequency combinations with single-frequency mode. It was found that all coupling parameters have a significant impact on acoustic cavitation, where the smaller values of f and φ were employed when β = 1, the stronger cavitation intensity was observed. Nevertheless, as the power allocation ratio is increased from 1 to 9 at φ = 0 for different frequency differences, the acoustic cavitation exhibits an attenuation trend. When the total acoustic power is evenly distributed, namely β = 1, the largest maximum expansion ratio (i.e. 12.96) was obtained at φ = 0 and f = 5 kHz, which represents a strongest cavitation effect. In addition, for different frequency combinations, the enhancement effect is found under the mixture of low and low frequency, whereas attenuation effect is generated easily by the combination of high and low frequency. Moreover, the effect become more pronounced as the proportion of high frequency component increases.