Yunhan Sun

Dr. Yunhan Sun

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 January 2022 in BioMed Research International
Verified
Journal Article
Open access
PDF file
HSHao Yu Shi
Hao Yu Shi
RPRunxuan Pang
Runxuan Pang
JYJing Yang
Jing Yang
DFDi Fan
Di Fan
HCHongXin Cai
HongXin Cai
YSYunhan Sun
Yunhan Sun
With the development of ceramic technology, prosthodontic ceramics are becoming a useful option for improving esthetic outcomes in dentistry. In this paper, various ceramic materials were reviewed and evaluated, and their advantages and disadvantages and indications in oral prosthodontics were analyzed objectively. The properties of resin‐based ceramics, polycrystalline ceramics, and silicate ceramics were compared and analyzed. Resin‐based ceramics may replace other ceramic materials in the CAD/CAM field.

1 January 2022 in BioMed Research International
Verified
Journal Article
Open access
PDF file
MZMi Zhang
Mi Zhang
ZZZili Zhou
Zili Zhou
JYJiahao Yun
Jiahao Yun
RLRui Liu
Rui Liu
JLJie Li
Jie Li
YSYunhan Sun
Yunhan Sun
This study is aimed at performing a systematic review and a network meta‐analysis of the effects of several membranes on vertical bone regeneration and clinical complications in guided bone regeneration (GBR) or guided tissue regeneration (GTR). We compared the effects of the following membranes: high‐density polytetrafluoroethylene (d‐PTFE), expanded polytetrafluoroethylene (e‐PTFE), crosslinked collagen membrane (CCM), noncrosslinked collagen membrane (CM), titanium mesh (TM), titanium mesh plus noncrosslinked (TM + CM), titanium mesh plus crosslinked (TM + CCM), titanium‐reinforced d‐PTFE, titanium‐reinforced e‐PTFE, polylactic acid (PLA), polyethylene glycol (PEG), and polylactic acid 910 (PLA910). Using the PICOS principles to help determine inclusion criteria, articles are collected using PubMed, Web of Science, and other databases. Assess the risk of deviation and the quality of evidence using the Cochrane Evaluation Manual, and GRADE. 27 articles were finally included. 19 articles were included in a network meta‐analysis with vertical bone increment as an outcome measure. The network meta‐analysis includes network diagrams, paired‐comparison forest diagrams, funnel diagrams, surface under the cumulative ranking curve (SUCRA) diagrams, and sensitivity analysis diagrams. SUCRA indicated that titanium‐reinforced d‐PTFE exhibited the highest vertical bone increment effect. Meanwhile, we analyzed the complications of 19 studies and found that soft tissue injury and membrane exposure were the most common complications.

8 June 2022 in Gels
Verified
Journal Article
Open access
PDF file
NCNaiyu Cui
Naiyu Cui
CDChun-Yu Dai
Chun-Yu Dai
XMXuran Mao
Xuran Mao
xun lvxun lv
xun lv
YGYue Gu
Yue Gu
YSYunhan Sun
Yunhan Sun
Poloxamer is a triblock copolymer with amphiphilicity and reversible thermal responsiveness and has wide application prospects in biomedical applications owing to its multifunctional properties. Poloxamer hydrogels play a crucial role in the field of tissue engineering and have been regarded as injectable scaffolds for loading cells or growth factors (GFs) in the last few years. Hydrogel micelles can maintain the integrity and stability of cells and GFs and form an appropriate vascular network at the application site, thus creating an appropriate microenvironment for cell growth, nerve growth, or bone integration. The injectability and low toxicity of poloxamer hydrogels make them a noninvasive method. In addition, they can also be good candidates for bio-inks, the raw material for three-dimensional (3D) printing. However, the potential of poloxamer hydrogels has not been fully explored owing to the complex biological challenges. In this review, the latest progress and cutting-edge research of poloxamer-based scaffolds in different fields of application such as the bone, vascular, cartilage, skin, nervous system, and organs in tissue engineering and 3D printing are reviewed, and the important roles of poloxamers in tissue engineering scaffolds are discussed in depth.

15 December 2021 in Pain Research and Management
Verified
Journal Article
Open access
PDF file
FLFei Li
Fei Li
YDYaoyao Diao
Yaoyao Diao
JWJiayin Wang
Jiayin Wang
XHXingyu Hou
Xingyu Hou
SQShuzhan Qiao
Shuzhan Qiao
HJHeng Bo Jiang
Heng Bo Jiang
Cracked tooth syndrome refers to a series of symptoms caused by cracked teeth. This article reviews the current literature on cracked tooth syndrome from four aspects, etiology, diagnosis, management, and prevention, to provide readers integrated information about this. The article begins with an introduction to the odontiatrogenic factors and then covers the noniatrogenic factors that induce cracked tooth syndrome. While the former discusses inappropriate root canal therapy and improper restorative procedures, the latter covers the topics such as the developmental and functional status of cracked tooth syndrome. This is then followed by the description of common clinical diagnosis methods, the prospects of new technologies, and summaries of current clinical management methods, including immediate management and direct and indirect restoration. In the final section, preventive methods and their importance are proposed, with the aim of educating the common population.

1 January 2022 in Bioinorganic Chemistry and Applications
Verified
Journal Article
Open access
PDF file
CZChuanYao Zhai
ChuanYao Zhai
CDChun Yu Dai
Chun Yu Dai
xun lvxun lv
xun lv
Biying ShiBiying Shi
Biying Shi
YLYu Ru Li
Yu Ru Li
HJHeng Bo Jiang
Heng Bo Jiang
After several years of research and development, it has been reported that magnesium alloys can be used as degradable metals in some medical device applications. Over the years, fluoride coatings have received increasing research attention for improving the corrosion resistance of magnesium. In this paper, different methods for preparing fluoride coatings and the characteristics of these coatings are reported for the first time. The influence of the preparation conditions of fluoride coatings, including the magnesium substrate, voltage, and electrolyte, on the coatings is discussed. Various properties of magnesium fluoride coatings are also summarized, with an emphasis on corrosion resistance, mechanical properties, and biocompatibility. We screened experiments and papers that planned the application of magnesium fluoride coatings in living organisms. We have selected the literature with the aim of enhancing the performance of in vivo implants for reading and further detailed classification. The authors searched PubMed, SCOPUS, Web of Science, and other databases for 688 relevant papers published between 2005 and 2021, citing 105 of them. The selected time range is the last 16 years. Furthermore, this paper systematically discusses future prospects and challenges related to the application of magnesium fluoride coatings to medical products.

27 August 2022 in Journal of Oncology
Verified
Journal Article
Open access
PDF file
YLYanli Li
Yanli Li
XLXuehan Li
Xuehan Li
RPRunxuan Pang
Runxuan Pang
GYGuang Yang
Guang Yang
MTMingxu Tian
Mingxu Tian
JHJian-min Han
Jian-min Han
In patients with head and neck cancer, irradiation (IR)-sensitive salivary gland (SG) tissue is highly prone to damage during radiotherapy (RT). This leads to SG hypofunction and xerostomia. Xerostomia is defined as the subjective complaint of dry mouth, which can cause other symptoms and adversely affect the quality of life. In recent years, diagnostic techniques have constantly improved with the emergence of more reliable and valid questionnaires as well as more accurate equipment for saliva flow rate measurement and imaging methods. Preventive measures such as the antioxidant MitoTEMPO, botulinum toxin (BoNT), and growth factors have been successfully applied in animal experiments, resulting in positive outcomes. Interventions, such as the new delivery methods of pilocarpine, edible saliva substitutes, acupuncture and electrical stimulation, gene transfer, and stem cell transplantation, have shown potential to alleviate or restore xerostomia in patients. The review summarizes the existing and new diagnostic methods for xerostomia, along with current and potential strategies for reducing IR-induced damage to SG function. We also aim to provide guidance on the advantages and disadvantages of the diagnostic methods. Additionally, most prevention and treatment methods remain in the stage of animal experiments, suggesting a need for further clinical research, among which we believe that antioxidants, gene transfer, and stem cell transplantation have broad prospects.