Application-specific multiprocessor systems-on-chip (MPSoCs) are usually designed by using a platform-based approach, where a wide range of customizable parameters can be tuned to find the best tradeoff in terms of the selected figures of merit (such as energy, delay, and area). This optimization phase is called design space exploration (DSE), and it usually consists of a multiobjective optimization problem with multiple constraints. So far, several heuristic techniques have been proposed to address the DSE problem for MPSoC, but they are not efficient enough for managing the application-specific constraints and for identifying the Pareto front. In this paper, an efficient DSE methodology for application-specific MPSoC is proposed. The methodology is efficient in the sense that it is capable of finding a set of good candidate architecture configurations by minimizing the number of simulations to be executed. The methodology combines the design of experiments (DoEs) and response surface modeling (RSM) techniques for managing system-level constraints. First, the DoE phase generates an initial plan of experiments used to create a coarse view of the target design space to be explored by simulations. Then, a set of RSM techniques is used to refine the simulation-based exploration by exploiting the application-specific constraints to identify the maximum number of feasible solutions. To trade off the accuracy and efficiency of the proposed techniques, a set of experimental results for the customization of a symmetric shared-memory on-chip multiprocessor with actual workloads has been reported in this paper.

Recent compilers offer a vast number of multilayered optimizations targeting different code segments of an application. Choosing among these optimizations can significantly impact the performance of the code being optimized. The selection of the right set of compiler optimizations for a particular code segment is a very hard problem, but finding the best ordering of these optimizations adds further complexity. Finding the best ordering represents a long standing problem in compilation research, named the phase-ordering problem. The traditional approach of constructing compiler heuristics to solve this problem simply cannot cope with the enormous complexity of choosing the right ordering of optimizations for every code segment in an application. This article proposes an automatic optimization framework we call MiCOMP, which Mitigates the Compiler Phase-ordering problem. We perform phase ordering of the optimizations in LLVM’s highest optimization level using optimization sub-sequences and machine learning. The idea is to cluster the optimization passes of LLVM’s O3 setting into different clusters to predict the speedup of a complete sequence of all the optimization clusters instead of having to deal with the ordering of more than 60 different individual optimizations. The predictive model uses (1) dynamic features, (2) an encoded version of the compiler sequence, and (3) an exploration heuristic to tackle the problem. Experimental results using the LLVM compiler framework and the Cbench suite show the effectiveness of the proposed clustering and encoding techniques to application-based reordering of passes, while using a number of predictive models. We perform statistical analysis on the results and compare against (1) random iterative compilation, (2) standard optimization levels, and (3) two recent prediction approaches. We show that MiCOMP’s iterative compilation using its sub-sequences can reach an average performance speedup of 1.31 (up to 1.51). Additionally, we demonstrate that MiCOMP’s prediction model outperforms the -O1, -O2, and -O3 optimization levels within using just a few predictions and reduces the prediction error rate down to only 5%. Overall, it achieves 90% of the available speedup by exploring less than 0.001% of the optimization space.

Security is gaining increasing relevance in the development of embedded devices. Towards a secure system at each level of design, this paper addresses security aspects related to network-on-chip (NoC) architectures, foreseen as the communication infrastructure of next-generation embedded devices. In the context of NoC-based multiprocessor systems, we focus on the topic, not yet thoroughly faced, of data protection. In this paper, we present a secure NoC architecture composed of a set of data protection units (DPUs) implemented within the network interfaces. The run-time configuration of the programmable part of the DPUs is managed by a central unit, the network security manager (NSM). The DPU, similar to a firewall, can check and limit the access rights (none, read, write, or both) of processors accessing data and instructions in a shared memory - in particular distinguishing between the operating roles (supervisor/user and secure/unsecure) of the processing elements. We explore different alternative implementations for the DPU and demonstrate how this unit does not affect the network latency if the memory request has the appropriate rights. We also focus on the dynamic updating of the DPUs to support their utilization in dynamic environments, and on the utilization of authentication techniques to increase the level of security.

The variety of today’s architectures forces programmers to spend a great deal of time porting and tuning application codes across different platforms. Compilers themselves need additional tuning, which has considerable complexity as the standard optimization levels, usually designed for the average case and the specific target architecture, often fail to bring the best results. This article proposes COBAYN : Compiler autotuning framework using BAYesian Networks, an approach for a compiler autotuning methodology using machine learning to speed up application performance and to reduce the cost of the compiler optimization phases. The proposed framework is based on the application characterization done dynamically by using independent microarchitecture features and Bayesian networks. The article also presents an evaluation based on using static analysis and hybrid feature collection approaches. In addition, the article compares Bayesian networks with respect to several state-of-the-art machine-learning models. Experiments were carried out on an ARM embedded platform and GCC compiler by considering two benchmark suites with 39 applications. The set of compiler configurations, selected by the model (less than 7% of the search space), demonstrated an application performance speedup of up to 4.6 × on Polybench (1.85 × on average) and 3.1 × on cBench (1.54 × on average) with respect to standard optimization levels. Moreover, the comparison of the proposed technique with (i) random iterative compilation, (ii) machine learning--based iterative compilation, and (iii) noniterative predictive modeling techniques shows, on average, 1.2 × , 1.37 × , and 1.48 × speedup, respectively. Finally, the proposed method demonstrates 4 × and 3 × speedup, respectively, on cBench and Polybench in terms of exploration efficiency given the same quality of the solutions generated by the random iterative compilation model.

Drug discovery is the most expensive, time-demanding, and challenging project in biopharmaceutical companies which aims at the identification and optimization of lead compounds from large-sized chemical libraries. The lead compounds should have high-affinity binding and specificity for a target associated with a disease, and, in addition, they should have favorable pharmacodynamic and pharmacokinetic properties (grouped as ADMET properties). Overall, drug discovery is a multivariable optimization and can be carried out in supercomputers using a reliable scoring function which is a measure of binding affinity or inhibition potential of the drug-like compound. The major problem is that the number of compounds in the chemical spaces is huge, making the computational drug discovery very demanding. However, it is cheaper and less time-consuming when compared to experimental high-throughput screening. As the problem is to find the most stable (global) minima for numerous protein–ligand complexes (on the order of 10${}^6$ to 10${}^{12}$), the parallel implementation of in silico virtual screening can be exploited to ensure drug discovery in affordable time. In this review, we discuss such implementations of parallelization algorithms in virtual screening programs. The nature of different scoring functions and search algorithms are discussed, together with a performance analysis of several docking softwares ported on high-performance computing architectures.

This paper presents a new attack against a software implementation of the Advanced Encryption Standard. The attack aims at flushing elements of the SBOX from the cache, thus inducing a cache miss during the encryption phase. The power trace is then used to detect when the cache miss occurs; if the miss happens in the first round of the AES then the information can be used to recover part of the secret key. The attack has been simulated using the Wattch simulation framework and a simple software implementation of AES (using a single table for the SBOX). The attack can be easily extended to more sophisticated versions of AES with more than one table. Eventually, we present a simple countermeasure which does not require randomization.