The risk of malignancy in thyroid nodules correlates with the presence of ultrasonographic features. In adults, ultrasound risk-classification systems have been proposed to indicate the need for further invasive diagnosis. Furthermore, elastography has been shown to support differential diagnosis of thyroid nodules. The purpose of our study was to assess the application of the American Thyroid Association (ATA), British Thyroid Association (BTA) ultrasound risk-classification systems and strain elastography in the management of thyroid nodules in children and adolescents from one center. Seventeen nodules with Bethesda III, IV, V and VI were selected from 165 focal lesions in children. All patients underwent ultrasonography and elastography followed by fine needle aspiration biopsy. Ultrasonographic features according to the ATA and BTA stratification systems were assessed retrospectively. The strain ratio in the group of thyroid nodules diagnosed as malignant was significantly higher than in benign nodules (6.07 vs. 3.09, p = 0.036). According to the ATA guidelines, 100% of malignant nodules were classified as high suspicion and 73% of benign nodules were assessed as low suspicion. Using the BTA U-score classification, 80% of malignant nodules were classified as cancerous (U5) and 20% as suspicious for malignancy (U4). Among benign nodules, 82% were classified as indeterminate or equivocal (U3) and 9% as benign (U2). Our results suggest that application of the ATA or BTA stratification system and elastography may be a suitable method for assessing the level of suspected malignancy in thyroid nodules in children and help make a clinical decision about the need for further invasive diagnosis of thyroid nodules in children.

Allergic contact dermatitis (ACD) is a frequent inflammatory and the most common type of occupational skin disease. Chloroacetophenone (CN) has been one of the most typical riot control agents known since the end of the First World War. It is used by the armed and police forces and as pocket tear gas for personal protection. However, it is considered to be safe and, therefore, should not cause fatal health effects. Although CN is stated to provoke ACD, there are only a few cases found in the literature similar to the one shown below. Allergic contact dermatitis (ACD) is a frequent inflammatory and the most common type of occupational skin disease. Chloroacetophenone (CN) has been one of the most typical riot control agents known since the end of the First World War. It is used by the armed and police forces and as pocket tear gas for personal protection. However, it is considered to be safe and, therefore, should not cause fatal health effects. Although CN is stated to provoke ACD, there are only a few cases found in the literature similar to the one shown below.