Fishes live in aquatic environments and several aquatic environmental factors have undergone recent alterations. The molecular mechanisms underlying fish responses to hypoxia and acidification stress have become a serious concern in recent years. This study revealed that hypoxia and acidification stress suppressed the growth of body length and height of the large yellow croaker (Larimichthys crocea). Subsequent transcriptome analyses of L. crocea juveniles under hypoxia, acidification, and hypoxia–acidification stress led to the identification of 5897 differentially expressed genes (DEGs) in the five groups. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses revealed that several DEGs were enriched in the ‘protein digestion and absorption’ pathway. Enrichment analysis revealed that this pathway was closely related to hypoxia and acidification stress in the five groups, and we found that genes of the collagen family may play a key role in this pathway. The zf-C2H2 transcription factor may play an important role in the hypoxia and acidification stress response, and novel genes were additionally identified. The results provide new clues for further research on the molecular mechanisms underlying hypoxia–acidification tolerance in L. crocea and provides a basic understanding of the potential combined effects of reduced pH and dissolved oxygen on Sciaenidae fishes.

Two typical fish products—fermented mandarin fish and semi-dried yellow croaker—are associated with biogenic amines (BAs), which are harmful to human health. The objective of this study was to investigate the bacterial ecology of the two fish products and to determine their capacity for producing BAs. Putrescine and cadaverine were major BAs detected in the fish products. Concentrations of BAs were significantly corrected with microbial count (p < 0.05). BA-producing isolates (33) in the two fish products were all multiple BA producers. Several of them, including Lactobacillus sakei, Bacillus cereus and Hafnia alvei isolated from fermented mandarin fish, as well as Shewanella baltica, Aeromonas veronii, and Photobacterium phosphoreum isolated from semi-dried yellow croaker, showed remarkable BA-producing capacity. Hafnia alvei produced the greatest abundance of putrescine, cadaverine, tyramine and 2-phenylethylamine. Lactobacillus sakei mainly produced tryptamine and putrescine. Photobacterium phosphoreum showed the strongest histamine-producing capacity.

Offshore and deep-sea aquaculture is increasingly recognized as a key pathway for expanding marine food production as nearshore resources decline and global demand for high-quality aquatic products grows. However, open-ocean farming operates under highly dynamic environmental conditions and long production cycles, which impose significant challenges on conventional experience-based management. This review synthesizes recent research on informatized management in offshore and deep-sea aquaculture and proposes a structured management framework based on five functional layers: perception, transmission, platform, decision, and execution. By systematically analyzing environmental constraints, technical bottlenecks, and management requirements, this framework integrates key technologies including the Internet of Things, unmanned surface and underwater vehicles, big data analytics, and artificial intelligence. The review further examines representative application scenarios, including environmental monitoring and early warning, intelligent feeding and nutrition management, disease prevention and control, and remote monitoring and management. Through cross-study comparison, this work highlights current limitations in system integration and long-term validation, while clarifying the technological pathways required for scalable and reliable offshore deployment. Overall, this review provides a conceptual foundation and technical reference for improving operational safety, production efficiency, and environmental sustainability in offshore and deep-sea aquaculture.