Dr. Silvia Marsoni is an internationally recognized leader in clinical trial design in oncology. She has developed a broad background in designing, implementing, and conducting Master translational protocols for clinical pipelines and therapeutic proof-of-concept trials, with a special focus on colorectal cancer. Her latest designed trial, PEGASUS, uses interventional post-surgery liquid biopsy to triage adjuvant treatment in early disease colon cancer patients and will serve as a platform for deciphering cancer evolution in space and time. (https://www.ifom.eu/en/cancer-research/programs/precision-oncology.php.)