The aim of this investigation was to perform a systematic review and meta-analysis to determine the efficacy of the acute ingestion of caffeine (from 3 to 6 mg/kg) to increase performance on variables related to team sports. A systematic review was performed in scientific databases from January to April 2018. All studies included had cross-over experimental designs comparing caffeine to an identical placebo condition. A meta-analysis was performed using the random effects model and pooled standardized mean differences (Glass’s Δ). Thirty-four studies published between 2001 and 2018 were included in the analysis. The meta-analysis revealed that caffeine increased single (Δ;95% confidence intervals = 0.19;0.14–0.25; p < 0.01) and repeated jump height (0.29;0.16–0.42; p < 0.01), single (0.16;0.02–0.30; p = 0.03) and repeated sprint velocity (0.14;0.03–0.25; p = 0.02), and reduced the time to complete agility tests (0.41;0.04–0.77; p = 0.03). During team sport matches, caffeine increased total running distance (0.41;0.20–0.62; p < 0.01), distance covered at sprint velocity (0.36;0.12–0.59; p < 0.01) and the number of sprints (0.44;0.18–0.69; p < 0.01). The acute ingestion of a moderate dose of caffeine had a small but significant positive effect on several aspects related to physical performance in team sports.

The ergogenic effect of acute caffeine ingestion has been widely investigated; however, scientific information regarding tolerance to the performance benefits of caffeine, when ingested on a day-to-day basis, is scarce. The aim of this investigation was to determine the time course of tolerance to the ergogenic effects of a moderate dose of caffeine. Eleven healthy active participants took part in a cross-over, double-blind, placebo-controlled experiment. In one treatment, they ingested 3 mg/kg/day of caffeine for 20 consecutive days while in another they ingested a placebo for 20 days. Each substance was administered daily in an opaque unidentifiable capsule, and the experimental trials started 45 min after capsule ingestion. Two days before, and three times per week during each 20-day treatment, aerobic peak power was measured with an incremental test to volitional fatigue (25 W/min) and aerobic peak power was measured with an adapted version of the Wingate test (15 s). In comparison to the placebo, the ingestion of caffeine increased peak cycling power in the incremental exercise test by ~4.0 ±1.3% for the first 15 days (P<0.05) but then this ergogenic effect lessened. Caffeine also increased peak cycling power during the Wingate test on days 1, 4, 15, and 18 of ingestion by ~4.9 ±0.9% (P<0.05). In both tests, the magnitude of the ergogenic effect of caffeine vs. placebo was higher on the first day of ingestion and then progressively decreased. These results show a continued ergogenic effect with the daily ingestion of caffeine for 15–18 days; however, the changes in the magnitude of this effect suggest progressive tolerance.

The ergogenic effect of caffeine is well-established, but the extent of its consumption in sport is unknown at the present. The use of caffeine was considered “prohibited” until 2004, but this stimulant was moved from the List of Prohibited Substances to the Monitoring Program of the World Anti-Doping Agency to control its use by monitoring urinary caffeine concentration after competition. However, there is no updated information about the change in the use of caffeine as the result of its inclusion in the Monitoring Program. The aim of this study was to describe the changes in urine caffeine concentration from 2004 to 2015. A total of 7488 urine samples obtained in official competitions held in Spain and corresponding to athletes competing in Olympic sports (2788 in 2004, 2543 in 2008, and 2157 in 2015) were analyzed for urine caffeine concentration. The percentage of samples with detectable caffeine (i.e., >0.1 μg/mL) increased from ~70.1%, in 2004–2008 to 75.7% in 2015. The median urine caffeine concentration in 2015 (0.85 μg/mL) was higher when compared to the median value obtained in 2004 (0.70 μg/mL; p < 0.05) and in 2008 (0.70 μg/mL; p < 0.05). The urine caffeine concentration significantly increased from 2004 to 2015 in aquatics, athletics, boxing, judo, football, weightlifting, and rowing (p < 0.05). However, the sports with the highest urine caffeine concentration in 2015 were cycling, athletics, and rowing. In summary, the concentration of caffeine in the urine samples obtained after competition in Olympic sports in Spain increased from 2004 to 2015, particularly in some disciplines. These data indicate that the use of caffeine has slightly increased since its removal from the list of banned substances, but urine caffeine concentrations suggest that the use of caffeine is moderate in most sport specialties. Athletes of individual sports or athletes of sports with an aerobic-like nature are more prone to using caffeine in competition.

The objective of this study is to determine the effects of a caffeine-containing energy drink on female volleyball players' performance. Thirteen elite female volleyball players ingested 3 mg·kg of caffeine with an energy drink or the same drink without caffeine (placebo drink) in a double-blind and randomized study. Then, participants performed the following: standing spike, jumping spike, spike jump, blocking jump, squat jump, countermovement jump, manual dynamometry, and the agility t-test. A simulated volleyball game was played, videotaped, and notated afterward. In comparison to the placebo drink, the ingestion of the caffeinated energy drink increased the ball velocity in the standing spike (19.2 ± 2.1 vs 19.7 ± 1.9 m·s, P = 0.023) and in the jumping spike (17.9 ± 2.2 vs 18.8 ± 2.2 m·s, P = 0.038) and the jump height in the squat jump (28.1 ± 3.2 vs 29.4 ± 3.6 cm, P = 0.028), countermovement jump (32.0 ± 4.6 vs 33.1 ± 4.5 cm, P = 0.018), spike jump (43.3 ± 4.7 vs 44.4 ± 5.0 cm, P = 0.025), and block jump (35.2 ± 5.1 vs 36.1 ± 5.1 cm, P = 0.044). Furthermore, the caffeinated energy drink decreased the time needed to complete the agility t-test (11.1 ± 0.5 vs 10.9 ± 0.3 s, P = 0.036). During the game, the volleyball actions categorized as successful were more frequent with the caffeinated energy drink (34% ± 9% vs 45% ± 9%, P < 0.001), whereas imprecise actions decreased (28% ± 7% vs 14% ± 9%, P < 0.001) when compared with the placebo drink. Commercially available energy drinks can significantly improve physical performance in female volleyball players. Increased physical performance led to improved accuracy during an actual volleyball match.