Manuel Iglesias-Garcia

Dr. Manuel Iglesias-Garcia

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
11 December 2023 in Equine Veterinary Journal
Verified
Journal Article
Open access
PHPablo Fernández Hernández
Pablo Fernández Hernández
MVMarta Valero‐González
Marta Valero‐González
UEUniversity of Extremadura
University of Extremadura
MIManuel Iglesias-Garcia
Manuel Iglesias-Garcia
Luis Javier Ezquerra CalvoLuis Javier Ezquerra Calvo
Luis Javier Ezquerra Calvo
BGBeatriz Macías García
Beatriz Macías García
Background: Currently, for in vitro embryo production in live mares, immature oocytes are retrieved by transvaginal follicular aspiration or ovum pick up (OPU). Occasionally, ovarian abscesses have been described after OPU, but no current consensus exists on how to treat this condition.Objectives: To describe diagnosis and successful treatment of ovarian abscesses in two mares subjected to OPU.Study design: Case report.Methods: Case records were reviewed and summarised.Results: In the first case, a pony mare showed tachypnoea, tachycardia, high temperature, leukocytosis, left hindlimb lameness and slight increase in concentration of serum amyloid A. Ultrasonography revealed an increase in the size of the left ovary and two well defined structures suggestive of ovarian abscess. A left ovariectomy by standing laparoscopy was the treatment of choice: the diagnosis was confirmed, and bacterial culture produced heavy growth of Streptococcus equi Zooepidemicus. In the second mare, an abnormal structure was observed in the left ovary in a routine transrectal ultrasonographic exam in the absence of any clinical signs or abnormal blood parameters. A medical approach was chosen and a sample of the purulent material was aspirated with a transvaginal ultrasound‐guided approach. The sample yielded a heavy growth of Streptococcus equi Zooepidemicus after culture. Treatment was initiated with rifampicin and trimethoprim—sulfadiazine based on the antibiogram results and the abscess completely resolved after 40 days.Main limitations: Limited to two cases.Conclusions: Ovarian abscesses in mares can be successfully treated both surgically and medically.

30 December 2021 in Animals
Verified
Journal Article
Open access
PDF file
UEUniversity of Extremadura
University of Extremadura
Alberto Muñoz-PrietoAlberto Muñoz-Prieto
Alberto Muñoz-Prieto
José J. CeronJosé J. Ceron
José J. Ceron
MMMaría Martín-Cuervo
María Martín-Cuervo
MIManuel Iglesias-Garcia
Manuel Iglesias-Garcia
ECElisa Diez de Castro
Elisa Diez de Castro
Obesity and its associated complications, such as metabolic syndrome, are an increasing problem in both humans and horses in the developed world. The expression patterns of resistin differ considerably between species. In rodents, resistin is expressed by adipocytes and is related to obesity and ID. In humans, resistin is predominantly produced by inflammatory cells, and resistin concentrations do not reflect the degree of obesity, although they may predict cardiovascular outcomes. The aim of this study was to investigate the usefulness of resistin and its relationship with ID and selected indicators of inflammation in horses. Seventy-two horses, included in one of the four following groups, were studied: healthy controls (C, n = 14), horses with inflammatory conditions (I, n = 21), horses with mild ID (ID1, n = 18), and horses with severe ID (ID2, n = 19). Plasma resistin concentrations were significantly different between groups and the higher values were recorded in the I and ID2 groups (C: 2.38 ± 1.69 ng/mL; I: 6.85 ± 8.38 ng/mL; ID1: 2.41 ± 2.70 ng/mL; ID2: 4.49 ± 3.08 ng/mL). Plasma resistin was not correlated with basal insulin concentrations. A significant (r = 0.336, p = 0.002) correlation was found between resistin and serum amyloid A. Our results show that, as is the case in humans, plasma resistin concentrations in horses are predominantly related to inflammatory conditions and not to ID. Horses with severe ID showed an elevation in resistin that may be secondary to the inflammatory status associated with metabolic syndrome.

27 May 2022 in Animals
Verified
Journal Article
Open access
PDF file
MIManuel Iglesias-Garcia
Manuel Iglesias-Garcia
IHIsabel Rodríguez Hurtado
Isabel Rodríguez Hurtado
Gustavo Ortiz-DíezGustavo Ortiz-Díez
Gustavo Ortiz-Díez
JBJorge De la Calle del Barrio
Jorge De la Calle del Barrio
CPCristina Fernandez Perez
Cristina Fernandez Perez
RLRaquel Gómez Lucas
Raquel Gómez Lucas
The extrinsic and intrinsic characteristics of an equine population may influence the onset of gastrointestinal lesions and affect the survival rate of patients. The equine population in Spain has been the focus of a small number of studies, none of which have involved more than one surgical center. In this retrospective cohort study, we aimed to analyze the survival rate, identify the variables that influenced death, and generate multivariate models using clinical variables. Data were collected from the clinical records of two surgical referral centers in the same region, and a total of 566 horses met the inclusion criteria. The statistical analysis was divided into three parts: The first and second included logistic analysis, in order to identify the variables most closely associated with survival. The third part assessed all previous variables in terms of survival and hospitalization time, using a COX survival analysis. The main risk factors associated with intra-operative mortality were related to seasonality (winter and summer), patient age (older than 9 years), distance from the hospital, the presence of a strangulating lesion, and the bowel segment affected (small intestine). Furthermore, the main factors associated with mortality during hospitalization were the characteristics of the lesions (strangulating) and the differences between surgical centers. The models generated in this study have good predictive value and use only reliable and easily obtainable variables. The most reliable characteristics are those related to the type of colic and the location of the lesion.

8 May 2025 in Journal of Equine Veterinary Science
Verified
Journal Article
Open access
DBDagmar Berner
Dagmar Berner
MHMaren Hellige
Maren Hellige
GHG.G. Harvey
G.G. Harvey
KGK. Gerlach
K. Gerlach
MIManuel Iglesias-Garcia
Manuel Iglesias-Garcia
GMGabriel Manso-Díaz
Gabriel Manso-Díaz
Paranasal sinus cysts (PSC) and progressive ethmoid haematomas (PEH) are regularly observed in the paranasal sinus system. Due to their different prognosis and treatment options, differentiation of both lesions prior to surgery on computed tomographic (CT) images is important for guidance. It was hypothesised that PSC and PEH can be reliably differentiated on CT images. The database of four European equine referral centres were retrospectively searched for horses that had undergone a CT examination of the head and had a confirmed PSC or PEH. Additionally, cases with confirmed sinusitis were selected as control cases. Images were anonymised and evaluated by different observers to investigate their ability to differentiate these diseases. Multiple imaging characteristics were evaluated for all diseases. Ninety-seven horses were included, final diagnosis was PEH in 24, PSC in 28, and sinusitis in 45 horses. Substantial to almost perfect agreement between CT diagnosis and final diagnosis for all three observers was found. Heterogeneity and attenuation of the lesion were graded significantly higher in PEH. Mineralisation within the soft tissue structure, inner and outer distortion of bone and soft tissues, a mineralised wall, and dental distortion were significantly more common in PSC. Only cases that subsequently underwent treatment were included, therefore, most cases were at an advanced stage. Histological examination was not available in all cases. Differentiation between PEH and PSC on CT images was excellent, and the reported different characteristics might help clinicians to distinguish between both diseases.

24 August 2019 in Veterinary Surgery
Verified
Journal Article
Closed access
PDF file
MIManuel Iglesias-Garcia
Manuel Iglesias-Garcia
IRImma Roquet
Imma Roquet
JJJoaquín Jiménez-Fragoso
Joaquín Jiménez-Fragoso
MMMaría Martín-Cuervo
María Martín-Cuervo
BFBeatriz Fuentes‐Romero
Beatriz Fuentes‐Romero
LELuis J. Ezquerra‐Calvo
Luis J. Ezquerra‐Calvo

10 May 2020 in Equine Veterinary Education
Verified
Journal Article
Closed access
PDF file
MIManuel Iglesias-Garcia
Manuel Iglesias-Garcia
OLOlivier M. Lepage
Olivier M. Lepage
LCL. J. Ezquerra Calvo
L. J. Ezquerra Calvo
JMJ. A. Muñoz Morán
J. A. Muñoz Morán