Shu Wang

Dr. Shu Wang

College of Health Solutions, Arizona State University Downtown Phoenix Campus, Phoenix, AZ 85004, USA
orcid

Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2014 in The Journal of Nutritional Biochemistry
Verified
Journal Article
Closed access
Shu WangShu Wang
Shu Wang
RSRui Su
Rui Su
SNShufang Nie
Shufang Nie
MSMing Sun
Ming Sun
JZJia Zhang
Jia Zhang
NMNaima Moustaid-Moussa
Naima Moustaid-Moussa

1 August 2018 in The Journal of Nutritional Biochemistry
Verified
Journal Article
Closed access
KAKembra Albracht-Schulte
Kembra Albracht-Schulte
NKNishan Kalupahana
Nishan Kalupahana
LRLatha Ramalingam
Latha Ramalingam
Shu WangShu Wang
Shu Wang
SRShaikh Mizanoor Rahman
Shaikh Mizanoor Rahman
Naima Moustaid-MoussaNaima Moustaid-Moussa
Naima Moustaid-Moussa

1 January 2014 in Colloids and Surfaces B: Biointerfaces
Verified
Journal Article
Closed access
MSMing Sun
Ming Sun
SNShufang Nie
Shufang Nie
XPXuan Pan
Xuan Pan
RZRuiwen Zhang
Ruiwen Zhang
ZFZhaoyang Fan
Zhaoyang Fan
Shu WangShu Wang
Shu Wang

19 March 2013 in Journal of Liposome Research
Verified
Journal Article
Closed access
RPRita Castillo Cohen de Pace
Rita Castillo Cohen de Pace
XLXinli Liu
Xinli Liu
MSMing Sun
Ming Sun
SNShufang Nie
Shufang Nie
JZJia Zhang
Jia Zhang
Shu WangShu Wang
Shu Wang
The chemopreventive actions exerted by green tea are thought to be due to its major polyphenol, (−)-epigallocatechin-3-gallate (EGCG). However, the low level of stability and bioavailability in the body makes administering EGCG at chemopreventive doses unrealistic. We synthesized EGCG encapsulated chitosan-coated nanoliposomes (CSLIPO-EGCG), and observed their antiproliferative and proapoptotic effect in MCF7 breast cancer cells. CSLIPO-EGCG significantly enhanced EGCG stability, improved sustained release, increased intracellular EGCG content in MCF7 cells, induced apoptosis of MCF7 cells, and inhibited MCF7 cell proliferation compared to native EGCG and void CSLIPO. The CSLIPO-EGCG retained its antiproliferative and proapoptotic effectiveness at 10 μM or lower, at which native EGCG does not have any beneficial effects. This study portends a potential breakthrough in the prevention or even treatment of breast cancer by using biocompatible and biodegradable CSLIPO-EGCG with enhanced chemopreventive efficacy and minimized immunogenicity and side-effects.

31 May 2016 in WIREs Nanomedicine and Nanobiotechnology
Verified
Journal Article
Closed access
PDF file
JZJia Zhang
Jia Zhang
YZYujiao Zu
Yujiao Zu
CDChathurika S. Dhanasekara
Chathurika S. Dhanasekara
JLJun Li
Jun Li
DWDayong Wu
Dayong Wu
Shu WangShu Wang
Shu Wang

1 April 2018 in Colloids and Surfaces B: Biointerfaces
Verified
Journal Article
Closed access
YZYujiao Zu
Yujiao Zu
HOHaley Overby
Haley Overby
GRGuofeng Ren
Guofeng Ren
ZFZhaoyang Fan
Zhaoyang Fan
Ling ZhaoLing Zhao
Ling Zhao
Shu WangShu Wang
Shu Wang