Marco Benadduci

Dr. Marco Benadduci

INRCA - Istituto Nazionale Riposo e Cura per Anziani
orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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EMElvira Maranesi
Elvira Maranesi
ECElisa Casoni
Elisa Casoni
RBRenato Baldoni
Renato Baldoni
IBIlaria Barboni
Ilaria Barboni
NRNadia Rinaldi
Nadia Rinaldi
RBRoberta Bevilacqua
Roberta Bevilacqua
(1) Background: Parkinson’s disease (PD) is one of the most frequent causes of disability among older people. Recently, virtual reality and exergaming have been emerged as promising tools for gait and balance rehabilitation in PD patients. Our purpose is to evaluate an innovative treatment for older patients with PD, based on non-immersive virtual reality exergames, improving gait and balance and reducing falling risk. (2) Methods: Thirty PD patients were recruited and randomly divided into two groups, to receive a traditional rehabilitation (CG) or a technological rehabilitation (TG). (3) Results: A statistical improvement of balance at the end of treatments was observed in both groups (CG: 12.4 ± 0.7 vs. 13.5 ± 0.8, p = 0.017; TG: 13.8 ± 0.5 vs. 14.7 ± 0.4, p = 0.004), while the overall risk of falling was significantly reduced only in the TG (POMA Total: 24.6 ± 0.9 vs. 25.9 ± 0.7, p = 0.010). The results between groups shows that all POMA scores differ in a statistically significant manner in the TG, emphasizing improvement not only in balance but also in gait characteristics (9.7 ± 0.8 vs. 11.4 ± 0.2, p = 0.003). Moreover, TG also improves the psychological sphere, measured thorough MSC-(17.1 ± 0.4 vs. 16.5 ± 0.4, p = 0.034). Although an improvement in FES-I and Gait Speed can be observed, this increase does not turn out to be significant. (4) Conclusions: Results suggest how non-immersive virtual reality exergaming technology offers the opportunity to effectively train cognitive and physical domains at the same time.

Giulio AmabiliGiulio Amabili
Giulio Amabili
GCGiacomo Cucchieri
Giacomo Cucchieri
AMArianna Margaritini
Arianna Margaritini
MBMarco Benadduci
Marco Benadduci
FBFederico Barbarossa
Federico Barbarossa
RBRoberta Bevilacqua
Roberta Bevilacqua
The aim of this paper is to describe the results collected with the Italian study conducted within eWare project, aimed at supporting the autonomy and health of the older people affected by dementia and their informal caregivers, through the use of an innovative system based on a social robot and a sensorized environmental infrastructure. Nine dyads of older participants with their caregivers were enrolled in testing the system for 6 months. The results show a positive impact of the system in supporting the achievement of personal goals of the participants, as well as in supporting the quality of life of the informal caregivers. Nevertheless, the impact of the system in reducing the caregivers’ burden needs to be deeply investigated. This research highlights the potential of the eWare system but modifications will have to be made, especially on the interactivity capabilities, in order to meet the peculiar needs and wishes of older people with dementia and to favor the long-term use of the system.

14 January 2025 in JMIR Aging
Verified
Journal Article
Open access
RBRoberta Bevilacqua
Roberta Bevilacqua
EMElvira Maranesi
Elvira Maranesi
MBMarco Benadduci
Marco Benadduci
GCGabriella Cortellessa
Gabriella Cortellessa
AUAlessandro Umbrico
Alessandro Umbrico
LRLorena Rossi
Lorena Rossi
Background: Parkinson disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms. Recently, dance has started to be considered an effective intervention for people with PD. Several findings in the literature emphasize the necessity for deeper exploration into the synergistic impacts of dance therapy and exergaming for PD management. Moreover, socially engaging robotic platforms equipped with advanced interaction and perception features offer potential for monitoring patients’ posture and enhancing workout routines with tailored cues. Objective: This paper presents the results of the Social Robotics for Active and Healthy Ageing (SI-Robotics) project, aimed at designing an innovative rehabilitation program targeted at seniors affected by (early-stage) PD. This study therefore aims to assess the usefulness of a dance-based rehabilitation program enriched by artificial intelligence–based exergames and contextual robotic assistance in improving motor function, balance, gait, and quality of life in patients with PD. The acceptability of the system is also investigated. Methods: The study is designed as a technical feasibility pilot to test the SI-Robotics system. For this study, 20 patients with PD were recruited. A total of 16 Irish dance–based rehabilitation sessions of 50 minutes were conducted (2 sessions per week, for 8 wks), involving 2 patients at a time. The designed rehabilitation session involves three main actors: (1) a therapist, (2) a patient, and (3) a socially interacting robot. To stimulate engagement, sessions were organized in the shape of exergames where an avatar shows patients the movements they should perform to correctly carry out a dance-based rehabilitation exercise. Results: Statistical analysis reveals a significant difference on the Performance-Oriented Mobility Assessment scale, both on balance and gait aspects, together with improvements in Short Physical Performance Battery, Unified Parkinson Disease Rating Scale–III, and Timed Up and Go test, underlying the usefulness of the rehabilitation intervention on the motor symptoms of PD. The analysis of the Unified Theory of Acceptance and Use of Technology subscales provided valuable insights into users’ perceptions and interactions with the system. Conclusions: This research underscores the promise of merging dance therapy with interactive exergaming on a robotic platform as an innovative strategy to enhance motor function, balance, gait, and overall quality of life for patients grappling with PD.

EMElvira Maranesi
Elvira Maranesi
VDValentina Di Donna
Valentina Di Donna
Giuseppe PelliccioniGiuseppe Pelliccioni
Giuseppe Pelliccioni
VCValentina Cameriere
Valentina Cameriere
ECElisa Casoni
Elisa Casoni
RBRoberta Bevilacqua
Roberta Bevilacqua
(1) Background: Parkinson’s Disease (PD) is one of the most common causes of disability among older individuals. The advanced stages of PD are usually characterized by postural instability and, as a consequence, falls. Those are among the main factors that determine the quality of life, as well as the morbidity and mortality of a person with PD. In the field of PD rehabilitation, robotics is also rapidly gaining ground. As a primary aim, we evaluate the acceptability of the technology integrated intervention, using the Psychosocial Impact of Assistive Devices Scale (PIADS), in order to analyze the attitude of the participants towards the Tymo® system. As a secondary outcome, we assess the result of the rehabilitation treatment integrated with the Tymo® system on several patient’s features. (2) Methods: We studied a population of 16 patients with Parkinson’s Disease. Each recruited subject completed 10 treatment sessions, organized as two training sessions per week, for 5 weeks. The intervention included 30 min of traditional therapy and 20 min of technological treatment with a robotic system. PIADS is composed of three subscales (Competence subscale, Adaptability subscale, Self-esteem subscale) ranging from −3 to +3, reflecting, respectively, a negative or positive feeling towards the device. (3) Results: The Competence subscale, measuring feelings of competence and usefulness, obtained a score of 1.24 (SD = 0.78). The score of Adaptability subscale, indicating a willingness to try out new things and to take risks, was 1.83 (SD = 0.65). Finally, the Self-esteem subscale, indicating feelings of emotional health and happiness, reached a score of 1.31 (SD = 0.72). Moreover, statistical analysis reveals a significant effect on balance performance after intervention. (4) Conclusions: This feasibility study represents a starting point in the use of technology in the rehabilitation pathway of patients affected by Parkinson’s Disease. In fact, our results suggest that a standard therapy combined with an innovative treatment using Tymo® may be accepted by PD patients, which may benefit especially from preserving balance.

24 December 2023 in Bioengineering
Verified
Journal Article
Open access
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Giulio AmabiliGiulio Amabili
Giulio Amabili
EMElvira Maranesi
Elvira Maranesi
AMArianna Margaritini
Arianna Margaritini
MBMarco Benadduci
Marco Benadduci
FBFederico Barbarossa
Federico Barbarossa
RBRoberta Bevilacqua
Roberta Bevilacqua
In Italy, many people aged over 65 cannot live independently, causing an overall decrease in their quality of life and a need for social and health care. Due to the lack of both formal and informal caregivers, technological solutions become of paramount importance in this scenario. This article describes the user-centered development of the GUARDIAN ecosystem, consisting of a social robot integrated with two mobile applications which aim to monitor, coach, and keep the older user company in order to prolong his/her independence at home. In particular, the advancements from the alpha to the beta prototype of the ecosystem are described, achieved through the feedback collected from 41 end users—older people and their carers—that have tested the system for 6 weeks. By enhancing human–robot interaction, a positive improvement in terms of usability and acceptability of the system was retrieved. However, to increase the perceived usefulness and the impact on older users’ lives, it is necessary to make the entire system more customizable, and more capable in providing support for daily activities.

2 September 2025 in JMIR Research Protocols
Verified
Journal Article
Open access
Giulio AmabiliGiulio Amabili
Giulio Amabili
EMElvira Maranesi
Elvira Maranesi
AMArianna Margaritini
Arianna Margaritini
ABAnna Rita Bonfigli
Anna Rita Bonfigli
EFElisa Felici
Elisa Felici
RBRoberta Bevilacqua
Roberta Bevilacqua
Background: Dementia is challenging society in terms of the quality of life, the costs of health care systems, and caregivers’ burden. Dementia is often preceded by a status of mild cognitive impairment (MCI), during which a healthy lifestyle and cognitive therapy seem to be effective in counteracting the decline. Objective: The engAGE (Managing Cognitive Decline Through Theatre Therapy, Artificial Intelligence, and Social Robot–Driven Interventions) project aimed to build a technological platform to counteract cognitive decline in older adults with MCI through both cognitive therapy and lifestyle management. Methods: The engAGE platform was built around the social robot Pepper, which provides cognitive therapy. An activity tracker and a mobile app were also integrated within the platform to help older adults with MCI monitor their sleep and physical activity, in addition to offering cognitive games at home. The proof of concept (PoC) of engAGE was designed as a 6-month long randomized controlled trial (RCT) aimed to test the solution in three European countries: Italy, Switzerland, and Norway. During this period, under the supervision of a psychologist or a therapist, Pepper provided cognitive therapy on a weekly basis at health care or daycare facilities. In parallel, the use of the mobile app and the activity tracker was recommended on a daily basis. Participants were recruited through health care institutions and care organizations and evaluated through face-to-face interviews. The primary interest of the study was to assess the impact of engAGE on cognitive capacity through the Montreal Cognitive Assessment (MoCA) and the Memory Assessment Clinic Questionnaire (MAC-Q). In addition, changes in social engagement and quality of life were measured through the University of California, Los Angeles (UCLA) Loneliness Scale and the Warwick-Edinburgh Mental Well-Being Scale (WEMWBS). The PoC also focused on the acceptability and usability of engAGE, evaluated through the System Usability Scale (SUS) and the Unified Theory of Acceptance and Use of Technology (UTAUT) questionnaire. In addition, data were collected regarding the frequency of weekly sessions and access to the mobile app, as well as activity tracker measurements. Results: Data collection commenced in November 2023 and finished in July 2024, with the enrollment of 49 older adults with MCI (n=40, 81.6%, assigned to the experimental group [EG] and n=9, 18.4%, to the control group [CG]) conducted from October 2023 to April 2024. Data analysis was concluded in November 2024, and results will be published by 2026. Conclusions: The engAGE PoC represents an innovative study focused on the impact of a technology-based multidomain intervention designed for older adults with MCI that aimed to counteract cognitive decline through cognitive training, as well as improvement in terms of the quality of life, social engagement, physical activity, and sleep quality of primary end users. Trial Registration: ClinicalTrials.gov NCT06302686; https://clinicaltrials.gov/study/NCT06302686 International Registered Report Identifier (IRRID): RR1-10.2196/67601