Łukasz Grabowski

Dr. Łukasz Grabowski

Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Mazowieckie, Poland
orcid

Biography

I am a researcher at the Department of Molecular Biology, Faculty of Biology, University of Gdańsk. My research focuses on the interactions between bacteriophages and eukaryotic cells, particularly immune system cells, and the safety of phage therapy applications in animals. I also investigate the mechanisms of eukaryotic cell death. Additionally, I explore natural compounds, primarily those derived from cyanobacteria, as potential anticancer agents by evaluating their cytotoxic potential and mechanisms of action. My most important publications include: a) Podlacha, M., Gaffke, L., Grabowski, Ł., Mantej, J., Grabski, M., Pierzchalska, M., Pierzynowska, K., Węgrzyn, G., & Węgrzyn, A. (2024). Bacteriophage DNA induces an interrupted immune response during phage therapy in a chicken model. Nature Communications, 15(1), 2274. [DOI: 10.1038/s41467-024-46555-7] b) Grabowski, Ł., Węgrzyn, G., Węgrzyn, A., & Podlacha, M. (2022). Highly different effects of phage therapy and antibiotic therapy on immunological responses of chickens infected with Salmonella enterica serovar Typhimurium. Frontiers in Immunology, 13, 956833. [DOI: 10.3389/fimmu.2022.956833] c) Grabowski, Ł., Węgrzyn, G., & Węgrzyn, A. (2024). Mechanisms of eukaryotic cell death induced by natural compounds from cyanobacteria. Apoptosis, 29(3), 345-359. [DOI: 10.1007/s10495-024-01937-6]

Affiliations

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

Warsaw, Mazowieckie, Poland

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Experience

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