In engineering blasting, the slope surfaces in the blasting area exert various effects on the blast vibration velocity. For example, the slope effect and the whipping effect are generated in the slope area, which will influence the blast vibration velocity. The slope area is the key protection area for many projects; therefore, it is of practical value to explore the influence of slope surface on blast vibration speed for the prediction of blast vibration and protection against it. The influence of slope effect and whipping effect on blast vibration velocity in the slope area was analyzed by numerical simulation and fitting. The field monitoring data were fitted to the blast vibration velocity prediction formula. According to the obtained fitting formula, we inferred that vibration speed amplification occurred in the slope area. Numerical simulation was carried out using the ANSYS/LS-DYNA program. Using the above two methods, whether the slope effect and whip tip effect occurred in the study area was verified. By numerical simulation, we established three-dimensional (3D) slope models for four different working conditions. We simulated the complete blasting process and the consistency between the simulation results, and the field data proved the reliability of the numerical simulation. Based on the results of the numerical simulation, we explored the variation of blasting vibration velocity under different height difference conditions. Finally, we explored the distribution law of blasting vibration at the slope surface and inside the slope.