Stein-Leventhal syndrome, often known as polycystic ovarian syndrome (PCOS), is a syndrome that affects women's reproductive health. PCOS is one of the most common endocrine and metabolic disorders in women of reproductive age. The etiology of PCOS remains unknown mainly, and the estimation of PCOS burden in a specific geographical location will impact disease control strategies. Hence, this study estimated the pooled prevalence of PCOS in Indian women. Databases such as PubMed, CINHAL, Scopus, and Google Scholar were thoroughly searched. Only those published Indian studies that reported the prevalence of PCOS from 2010 to 2021 and had at least one of the following diagnostic PCOS criteria were included in the systematic review: the National Institutes of Health (NIH), Rotterdam's criteria, or/and Androgen Excess Society (AES). MetaXL version 5.3 software was used for data analysis. The risk of bias was assessed using modified Joanna Briggs Institute criteria for cross-sectional studies. Out of 17132 articles, 11 articles were selected for systematic review and meta-analysis. The pooled prevalence of PCOS was 11.33(7.69-15.59) using the random effect. The proportion of Hirsute using the Ferriman-Gallwey score was highly variable, ranging from 1.6% to 37.9% (n=6). The prevalence rate of PCOS is high among Indian women. The pooled prevalence of PCOS was close to 10% using Rotterdam's criteria and AES criteria, while it was 5.8% using NIH criteria. The study's overall finding emphasizes the need for more acceptable and uniform diagnostic criteria for screening PCOS. At the same time, policy-makers should consider giving more importance to PCOS in their effort to control non-communicable diseases.
Soil contains diverse and complex natural elements having physical, chemical, mineralogical and biological components. Soil being a transferable physical component (it can be transferred from one location to another with the help of shoes, tires, clothes, tools etc.), acts as a tool of forensic investigation to correlate a specific crime scene with criminal suspects. A variety of techniques and combinations of methods can be used to discriminate soil from different geographical locations. The present review highlights various analytical techniques (ATR-FTIR, pyGC-MS, SEM-EDX, ICP-MS/OES and XRD) for soil analysis (colour comparison, texture and particle size determination, density gradient methods and organic matter estimation) and discusses some of the famous cases solved with soil trace evidence. The objective of the present study is to provide an overview of the importance of soil as physical evidence in forensic science based on literature analysis that will help forensic scientists and researchers to select appropriate methods to discriminate different soil samples. This article reviews various analytical techniques used to differentiate soils and provides compiled information regarding soil as trace evidence in order to help academicians, researchers and forensic soil scientists.
17 May 2022 in Journal of Evidence-Based Dental Practice
Aim and Objectives The aim and objectives of present study was to record the vertical measurements of mental foramen and to correlate them to assess the sensitivity of these parameters in gender determination. Methodology Panoramic radiographs of a 100 individuals including 50 males and 50 females were assessed by using three linear vertical measurements and after that data was statistically analyzed. Results Statistically significant differences were observed in all of the linear measurements between genders where males almost have higher measurements than females. Conclusion This study concludes that the distances from the superior border of alveolar ridge to the superior margin of mental foramen of the mandible exhibit sexual dimorphism in the Haryana population.
Background Maternal mortality rates show disproportional disparities among disadvantaged groups. Objective To conduct an overview of qualitative systematic reviews to summarise the antenatal care experience of ethnic minority and underserved, marginalised and disadvantaged women in high-income countries. Search strategy Seven electronic databases were searched to identify reviews published between 2011-2022. Selection criteria Two reviewers independently screened search results and full texts of potentially eligible articles. Data collection and analysis Data were extracted by two independent reviewers, critically appraised using the JBI tool and assessed for overlap. A thematic analysis was conducted. Main results Nineteen qualitative reviews were included. Most were conducted in the UK (n=12) and provided a thematic synthesis of findings. Studied populations included women from minority ethnic groups and those who were migrants, homeless, refugees, asylum seekers, disabled, obese, or had experienced genital mutilation or human trafficking. Common challenges included language and cultural differences, and lack of effective interactions with healthcare professionals. Many women experienced discrimination, isolation, limited awareness of available services and negative attitudes from maternity care staff. Limited access to maternity services was influenced by various factors, including costs and communication barriers. Positive experiences included interactions with culturally responsive healthcare professionals, support from social groups, and access to interpreters. Conclusions Our findings highlight the complex challenges some women face during maternity care. Future research should focus on more personalised care solutions, long-term evaluations of maternity services, training of healthcare professionals, and ways to improve the quality of information provided and the interaction with healthcare professionals.
16 September 2023 in European Journal of Obstetrics & Gynecology and Reproductive Biology
Choroid plexus cysts (CPCs) are incidental findings on ultrasound examination of the fetal brain. It is not known if isolated CPCs are associated with any adverse health or neurodevelopmental outcomes during the life course. This systematic review aimed to collate and synthesize the evidence on whether or not isolated choroid plexus cysts are associated with an increased risk of adverse health or developmental outcomes during childhood and adolescence. A search strategy was developed specifically for this study and applied to four electronic databases Medline (Ovid), Embase (Ovid), Web of Science, and Google Scholar. Studies were assessed and selected for inclusion if there was a measurement of CPC (including single or multiple; unilateral or bilateral; isolated or presenting alongside other markers) during the antenatal or early neonatal period (<7 days) with follow-up of children and adolescents for health and developmental outcomes measured at any time from age 1 month onwards. Study quality was assessed using the Newcastle-Ottawa Quality Assessment Scale. Due to heterogeneity in the types of outcome measures included and the timing of measurement of outcomes across the studies, it was not possible to pool data across studies and a narrative description of findings was presented. Eight studies (three cohorts and five case series) met the inclusion criteria. Different methods were used for outcome assessment, such as in-person assessment, parent questionnaires, medical records, and telephone interviews with parents. Six studies measured outcomes only once during the specified duration of follow-up; two studies carried out paediatric reviews of the children several times during follow-up. There were no differences in developmental outcomes or physical health between babies with CPCs reported in the three cohort studies, and no abnormalities were detected in the children that were followed up in four of the five case series studies. Most of the included studies were graded as low quality due to the small sample size, high risk of selection bias, unclear definitions of CPC or lack of a comparison group. The studies conducted to date do not provide evidence of adverse physical health outcomes or neurodevelopmental delays in babies with CPCs. However, most of these studies were small and included a narrow range of outcomes. Further research is needed to explore the relative incidence of outcomes such as ASD, ADHD, epilepsy and educational attainment in children with CPCs.