This study monitored indoor environmental data in 144 classrooms in 31 schools in the Midwestern United States for two consecutive days every fall, winter, and spring during a two-year period; 3,105 pupils attended classrooms where the measurements were conducted. All classrooms were ventilated with mechanical systems that had recirculation; there were no operable exterior windows or doors. The daily absence rate at the student level and demographic data at the classroom level were collected. The overall mean ventilation rate, using outdoor air, was 5.5 L/s per person (the corresponding mean carbon dioxide concentrations were < 2,000 ppm), and the mean indoor PM_2.5 was 3.6 μg/m³. The annual illness-related absence rate at the classroom level was extracted from the student-level absence data and regressed on measured indoor environmental parameters. Significant associations were found. Every 1 L/s per person increase in ventilation rate was associated with a 5.59 decrease in days with absences per year. This corresponds to a 0.15% increase in the annual daily attendance rate. Every additional 1 μg/m³ of indoor PM_2.5 was associated with a 7.37 increase in days with absences per year. This corresponds to a 0.19% decrease in the annual daily attendance rate. No other relationships were significant. Present results agree with the previously demonstrated benefits of reduced absence rates when classroom ventilation is improved and provide additional evidence on the potential benefits of reducing indoor inhalable particles. Overall, reduced absence rates are expected to provide socioeconomic benefits and benefits for academic achievements, while higher ventilation rates and reduced particle levels will also contribute to reduced health risks, including those related to airborne respiratory pathogens.

Demand controlled ventilation (DCV) is used to reduce the system outdoor airflow (OA) when the occupancy of the system is under design occupancy. However, the new versions of ASHRAE Standard 62.1-2010 make DCV more difficult to implement for multiple zone HVAC systems. This article proposes a CO₂-based and occupancy-sensor-based dynamic reset of OA rate for multiple zone HVAC systems (“CO₂-based DR”). This control strategy uses bioeffluent load estimation with a steady-state assumption to calculate and dynamically reset the system OA rate minimum set-point by solving the multiple-zone system equations for current conditions. Building energy and airflow simulations were implemented to assess the energy performance and indoor air quality of this control strategy. The simulation results showed that the average annual system OA rate for CO₂-based DR is 14.6% less than the OA rate for without DCV, in which case the system OA is always maintained as constant. The annual monetary saving as a percentage of the baseline case (without DCV) is between 0.3% and 11.0% for 16 climate zones in the United States.

(1) The association of the indoor environmental conditions in classrooms with illness-related absenteeism (IRA) was not well investigated. In addition, studying the association between heating and non-heating seasons were very limited; (2) To fill this knowledge gap, a research team collected various indoor air quality (IAQ) and thermal comfort conditions (TC) of 85 elementary classrooms in two school districts from the Midwestern United States throughout an academic year; in total, 255 classroom visits were performed. A negative binomial regression model was implied to associate the classroom’s IAQ and TC with IRA, separating for heating and non-heating seasons; (3) During non-heating season, a 3% increase of IRA was estimated with 1,000,000-counts/L increase of particles that had a diameter less than 2.5 μm (PN2.5); during the heating season, a 3% increase of IRA were expected with 100 ppm increase of room averaged CO₂ concentration; and (4) These results suggested that the IAQ and TC factors could associated with IRA differently between heating and non-heating seasons.

Recently, the requirement to continuously collect bioaerosol samples using shorter response times has called for the use of real-time detection. The decreased cost of this technology makes it available for a wider application than military use, and makes it accessible to pharmaceutical and academic research. In this case study, real-time bioaerosol monitors (RBMs) were applied in elementary school classrooms—a densely occupied environment—along with upper-room ultraviolet germicidal irradiation (UVGI) devices. The classrooms were separated into a UVGI group and a non-UVGI control group. Fluorescent bioaerosol counts (FBCs) were monitored on 20 visiting days over a four-month period. The classroom with upper-room UVGI showed significantly lower concentrations of fine size (<3 μm) and total FBCs than the control classroom during 13 of the 20 visiting days. The results of the study indicate that the upper-room UVGI could be effective in reducing FBCs in the school environment, and RBMs may be applicable in reflecting the transient conditions of the classrooms due to the dynamic activity levels of the students and teachers.

Upper room ultraviolet germicidal irradiance (UVGI) has been shown to reduce the concentration of bioaerosols in controlled chambers. However, there is a lack of experimental results on the reduction of bioaerosol concentrations by UVGI devices in actual uncontrolled buildings. This study was carried out in an American elementary school in the Midwest. Two sampling procedures were carried out in six selected classrooms with similar dimensions that were separated into two groups: (1) UVGI exposure group and (2) non-UVGI control group. Two-stage Tisch culturable impactors were utilized to collect airborne culturable bacteria and fungi. Monthly samples were collected during unoccupied period in sampling Procedure A and during close-to-occupied periods in sampling Procedure B. Student absenteeism data were collected. Nonparametric statistical methods were applied. Neither analysis of microorganisms nor student absenteeism showed a significant difference between the UVGI exposure and non-UVGI control groups in Procedure A. Analysis of the airborne culturable fine and total bacteria levels (1–8 µm) was significantly lower in the exposure classroom than those of the control classroom using Procedure B (P values < 0.05). The result indicates that collecting airborne bacteria close to occupied time could be more effective in evaluating the performance of upper room UVGI. In this case study, upper room UVGI can reduce culturable bioaerosols in a crowed environment like classrooms.