A newborn girl with histologically confirmed epulis presented with a 2.6-cm mass protruding from her mouth. An ultrasound study performed in antenatal week 25 was unremarkable. Postnatal ultrasound showed a mass, hyperechoic centrally, hypoechoic peripherally, containing crowded branching vessels. MRI revealed a nonenhancing gingival mass exhibiting an isointense rim on T1-weighted imaging and a low-intensity rim on T2-weighted sequences. MRI better defined its gingival origin and lack of local extension. A gingival solid mass in a newborn with branching vessels and a peripheral rim on imaging may suggest congenital epulis.

The aim of this study is to investigate the possibility of predicting histological grade in patients with endometrial cancer on the basis of intravoxel incoherent motion (IVIM)-related histogram analysis parameters. This prospective study included 52 women with endometrial cancer (EC) who underwent MR imaging as initial staging in our hospital, allocated into low-grade (G1 and G2) and high-grade (G3) tumors according to the pathology reports. Regions of interest (ROIs) were drawn on the diffusion weighted images and apparent diffusion coefficient (ADC), true diffusivity (D), and perfusion fraction (f) using diffusion models were computed. Mean, median, skewness, kurtosis, and interquartile range (IQR) were calculated from the whole-tumor histogram. The IQR of the diffusion coefficient (D) was significantly lower in the low-grade tumors from that of the high-grade group with an adjusted p-value of less than 5% (0.048). The ROC curve analysis results of the statistically significant IQR of the D yielded an accuracy, sensitivity, and specificity of 74.5%, 70.1%, and 76.5% respectively, for discriminating low from high-grade tumors, with an optimal cutoff of 0.206 (×10⁻³ mm²/s) and an AUC of 75.4% (95% CI: 62.1 to 88.8). The IVIM modeling coupled with histogram analysis techniques is promising for preoperative differentiation between low- and high-grade EC tumors.