In this work, the photophysical characteristics of [Cu(N^N)₂]⁺ and [Cu(N^N)(P^P)]⁺ complexes were described. The concept of thermally activated delayed fluorescence (TADF) and its development throughout the years was also explained. The importance of ΔE (S₁–T₁) and spin-orbital coupling (SOC) values on the TADF behavior of [Cu(N^N)₂]⁺ and [Cu(N^N)(P^P)]⁺ complexes is discussed. Examples of ΔE (S₁–T₁) values reported in the literature were collected and some trends were proposed (e.g. the effect of the substituents at the 2,9 positions of the phenanthroline ligand). Besides, the techniques (or calculation methods) used for determining ΔE (S₁–T₁) values were described. The effect of SOC in TADF was also discussed, and examples of the determination of SOC values by DFT and TD-DFT calculations are provided. The last chapter covers the applications of [Cu(N^N)₂]⁺ and [Cu(N^N)(P^P)]⁺ TADF complexes and the challenges that are still needed to be addressed to ensure the industrial applications of these compounds.

Zinc oxide nanoparticles were successfully synthesized under precipitation processes, using ZnSO4·7H2O as a Zn2+ precursor and K2CO3 used as a basic source, and hydrozincite was obtained as an intermediary, which was treated under two procedures; first procedure involved multiple stages to get final precipitated with NaOH, and in the second procedure the hydrozincite was straightforwardly dried at 220 °C. By both processes ZnO structures were obtained, which were turned into nanoparticles by a solvothermal treatment, for four hours in ethylene glycol at 200 °C. The final products for the first procedure was conglomerate of spherical nanoparticles with sizes ranged between 5–10 nm and dispersed ellipsoidal nanoparticles for the second procedure.

We report the comparative study of the electrochemical and photoluminescent properties of two Ir(III) complexes described as [Ir(F₂ppy)₂(N^N)][PF₆], where the F₂ppy ligand is 2-(2,4-difluorophenyl)pyridine and the N^N ligands are pyrazino[2,3-f][1,10]phenanthroline (ppl) and pyrazino[2,3-f][4,7]phenanthroline (ppz). The complexes were used for the fabrication of light-emitting electrochemical cells (LECs). The structures of the complexes have been corroborated by X-ray crystallography. Theoretical calculations were performed to understand the photophysical behavior of the complexes. Both in solution and solid state, the photoluminescence spectra shows that emission is significantly red-shifted in the [Ir(F₂ppy)₂(ppz)][PF₆] complex compared with the [Ir(F₂ppy)₂(ppl)][PF₆] complex. Besides, the [Ir(F₂ppy)₂(ppl)][PF₆] complex exhibits a higher quantum yield and a longer excited state lifetime than the [Ir(F₂ppy)₂(ppz)][PF₆] complex; therefore, in the last case non-radiative decay is predominant due to the stabilization of LUMO orbital (energy gap law). In the fabrication of LEC devices with the [Ir(F₂ppy)₂(ppl)][PF₆] complex, light emission was obtained with a maximum value of luminance equal to 177 cd m⁻², while in the case of the [Ir(F₂ppy)₂(ppz)][PF₆] complex, no luminance was observed. According to the photophysical data, the performance in LEC devices could be explained by the different position of the nitrogens in the ppl and ppz structural isomers, electronically affecting the complex, and therefore its properties. In addition, from the crystallographic analysis it is possible to note that the [Ir(F₂ppy)₂(ppz)][PF₆] complex shows enhanced intermolecular and intramolecular interactions compared with [Ir(F₂ppy)₂(ppl)][PF₆], and consequently a higher ordering of the molecules in the complex with ppz ligand can be expected. This higher order could favour the quenching processes, and consequently enhance the non-radiative deactivation.

The synthesis and the electrochemical, photoluminescent and electroluminescent properties is reported for two new Ir(iii) cyclometalated complexes described as [Ir(F₂ppy)₂L1](PF₆) and [Ir(F₂ppy)₂L2](PF₆).

Background: The extended-spectrum beta-lactamase (ESBL) Klebsiella pneumoniae is one of the leading causes of health-associated infections (HAIs), whose antibiotic treatments have been severely reduced. Moreover, HAI bacteria may harbor pathogenic factors such as siderophores, enzymes, or capsules, which increase the virulence of these strains. Thus, new therapies, such as antimicrobial photodynamic inactivation (aPDI), are needed. Method: A collection of 118 clinical isolates of K. pneumoniae was characterized by susceptibility and virulence through the determination of the minimum inhibitory concentration (MIC) of amikacin (Amk), cefotaxime (Cfx), ceftazidime (Cfz), imipenem (Imp), meropenem (Mer), and piperacillin–tazobactam (Pip–Taz); and, by PCR, the frequency of the virulence genes K2, magA, rmpA, entB, ybtS, and allS. Susceptibility to innate immunity, such as human serum, macrophages, and polymorphonuclear cells, was tested. All the strains were tested for sensitivity to the photosensitizer PSIR-3 (4 µg/mL) in a 17 µW/cm² for 30 min aPDI. Results: A significantly higher frequency of virulence genes in ESBL than non-ESBL bacteria was observed. The isolates of the genotype K2+, ybtS+, and allS+ display enhanced virulence, since they showed higher resistance to human serum, as well as to phagocytosis. All strains are susceptible to the aPDI with PSIR-3 decreasing viability in 3log10. The combined treatment with Cfx improved the aPDI to 6log10 for the ESBL strains. The combined treatment is synergistic, as it showed a fractional inhibitory concentration (FIC) index value of 0.15. Conclusions: The aPDI effectively inhibits clinical isolates of K. pneumoniae, including the riskier strains of ESBL-producing bacteria and the K2+, ybtS+, and allS+ genotype. The aPDI with PSIR-3 is synergistic with Cfx.