Maria Gloria Nardi

Dr. Maria Gloria Nardi

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Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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20 October 2023 in Dentistry Journal
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Journal Article
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MPMaurizio Pascadopoli
Maurizio Pascadopoli
PBPaolo Zampetti Branchini
Paolo Zampetti Branchini
MNMaria Gloria Nardi
Maria Gloria Nardi
Matteo PellegriniMatteo Pellegrini
Matteo Pellegrini
Andrea ScribanteAndrea Scribante
Andrea Scribante
This scoping review aims to investigate the latest literature concerning the use of smartphone applications (apps) in the prevention, management, and monitoring of oral diseases. Smartphone applications are software programs that are designed to run on smartphones. Nowadays, smartphones are regularly used by people of all ages, and mobile health apps (MHAs) represent an important means of spreading information related to oral health, which is the state of the mouth and teeth, including the gums and other tissues. Several apps have been designed to promote prevention, diagnosis, and therapeutic adherence monitoring. This scoping review considered randomized clinical trials, cross-sectional studies, before–after (pre–post) studies with no control group, and observational studies. Once the inclusion and exclusion criteria had been defined, a preliminary confined search was performed on PubMed and Scopus; key terms from the collected articles were selected to design a search strategy, and then a search of all the included articles’ reference lists was run for further research. Studies were excluded if they did not fulfill the inclusion criteria. The preferred reporting items for scoping reviews (PRISMA-ScR) consensus was followed. The risk of bias was evaluated by providing a qualitative analysis of the clinical studies via the National Heart, Lung, and Blood Institute (NHLBI) Quality Assessment of Controlled Intervention Studies, Observational Cohort Studies, and Cross-Sectional Studies (NHLBI, NIH). A total of 21 studies were included in this review. As it is clear from the studies selected, the literature indicates that MHAs are effective in improving oral hygiene in adolescents and children and reducing the dental plaque index, including in patients undergoing orthodontic treatment. MHAs are also able to reduce the symptoms of patients affected by obstructive sleep apnea–hypopnea syndrome (OSAHS) and improve the swallowing-related quality of life of elderly patients. MHAs are furthermore recommended to decrease dental anxiety among patients, both during dental procedures and the post-operative period. MHAs are useful to spread knowledge about traumatic dental injuries among non-oral health professionals and to monitor dental erosion and awake bruxism. MHAs’ clinical outcomes might have been influenced by the demographic features of the subjects involved. Further studies considering a longer follow-up period and larger samples are needed. In conclusion, MHAs can be considered a useful tool to monitor oral disease and increase patients’ quality of life related to oral health.

19 April 2024 in Dentistry Journal
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Journal Article
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Andrea ButeraAndrea Butera
Andrea Butera
MPMaurizio Pascadopoli
Maurizio Pascadopoli
MNMaria Gloria Nardi
Maria Gloria Nardi
COChiara Ogliari
Chiara Ogliari
ACAlessandro Chiesa
Alessandro Chiesa
Andrea ScribanteAndrea Scribante
Andrea Scribante
Periodontal disease is very common in pregnant women. Paraprobiotics are a subset of probiotics. They can be defined as inactivated microbial cells providing health benefits to the host and are considered particularly safe. The aim of this study was to compare the periodontal health of pregnant women and puerperae after 6 months of home use of paraprobiotics. A total of 30 pregnant women were enrolled and divided into two groups: the test group, who had to use a paraprobiotic-based toothpaste (Biorepair Peribioma Pro, Coswell S.p.A., Funo di Argelato, BO, Italy) and mousse (Mousse Mouthwash Biorepair Peribioma, Coswell S.p.A.) twice a day, and the control group, who had to use only the paraprobiotic-based toothpaste. The time frames of the study were: 1 month (T1), 3 months (T2) and 6 months (T3), and data were collected during pregnancy and in the period immediately following delivery. The following indices were evaluated at T0, T1, T2 and T3: clinical attachment loss (CAL), probing pocket depth (PPD), bleeding on probing (BOP), plaque control record (PCR), modified marginal gingival index (mMGI), papillary marginal gingival index (PMGI) and recessions (R). All data were subjected to statistical analysis. PCR decreased significantly from T0 to T1 in the control group and from T0 to T2 and from T0 to T3 in the test group. BOP tended to decrease in both groups, but a significant reduction was observed only in the test group. CAL, PPD, PMGI and mMGI tended to decrease gradually in both groups without significant differences between or within groups. The combination of the paraprobiotic-based toothpaste and the paraprobiotic-based mousse significantly reduced BoP and plaque control over time, although there were no significant differences with the use of the paraprobiotic-based toothpaste alone. In addition, the combination of the two products promoted a trend towards the better stabilization of recessions.

24 April 2022 in Applied Sciences
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Maria Francesca SfondriniMaria Francesca Sfondrini
Maria Francesca Sfondrini
MPMaurizio Pascadopoli
Maurizio Pascadopoli
SDSerena Dicorato
Serena Dicorato
CTClaudia Todaro
Claudia Todaro
MNMaria Gloria Nardi
Maria Gloria Nardi
Andrea ScribanteAndrea Scribante
Andrea Scribante
Cone-beam computed tomography (CBCT) allows for more accurate 3D study of the craniofacial region and the development of a very precise treatment plan. The present pilot study aims to evaluate the skeletal outcomes of the rapid maxillary expander (RME) on the sagittal, transverse and vertical planes in growing patients subjected to CBCT at T0 and T1, and to compare the results from two different programs. The effects of the RME are monitored in 11 patients who were subjected to CBCT at T0, before the expansion, and at T1, 6 months after the end of the RME therapy. The results obtained are evaluated using two programs: Simplant and Delta-Dent. All of the analyses were performed by the same operator. Both programs reported statistically significant differences between the pre- and post-expansion values of the parameters on the transverse plane. On the vertical plane, only posterior facial height showed a statistically relevant variation. Both programs underlined a discrepancy between the pre- and post-expansion infraorbital and mental foramina distance values; however, this difference was considered statistically significant by Delta-Dent, and not by Simplant. CBCT is a reliable and effective tool for orthodontic diagnosis and treatment planning. Both of the evaluated programs are efficient in tridimensional cephalometric analysis.

26 October 2023 in The Open Dentistry Journal
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Journal Article
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Matteo PellegriniMatteo Pellegrini
Matteo Pellegrini
MNMaria Gloria Nardi
Maria Gloria Nardi
Federica PulicariFederica Pulicari
Federica Pulicari
Andrea ScribanteAndrea Scribante
Andrea Scribante
Umberto GaragiolaUmberto Garagiola
Umberto Garagiola
FSFrancesco Spadari
Francesco Spadari
Background: Orthognathic surgery is often applied for the correction of facial dysmorphia, and different findings were highlighted regarding the techniques applied. After surgical treatment, intermaxillary fixation is placed, which compromises oral hygiene and, consequently, can lead to increased plaque accumulation and microbiological changes, promoting the proliferation of periodontopathogenic bacteria. Therefore, the aims of the present review are to describe the main evidence from the last 20 years of clinical studies concerning surgical techniques applied to orthognathic surgery and, finally, to analyze potential changes in the oral microbiota. Materials and Methods: An electronic search was conducted in the PubMed (MEDLINE) and Scopus databases; the MeSH (Medical Subject Heading) terms are bacteria, dental plaque, evidence-based practice, maxillomandibular fixation, microbiota, operative procedures, and orthognathic surgery. Results: At the end of the search process, 31 relevant articles were finally included and analyzed in this systematic review, which has a low risk of bias. Clinical studies on humans have been considered in this review. Based on the studies included it would be preferable to use piezoelectric technology in osteotomies because of its many advantages, “surgery-first” technique allows for results comparable to the standard technique in Class III malocclusions while improving quality of life more rapidly, the “mandible-first” technique seems to have more advantages than the “maxilla-first” technique, Computer-Aided Design and Manufacturing (CAD/CAM) could provide more accurate and precise results, and finally, Laser can be applied with different advantages. Regarding intermaxillary fixation, no long-term increase in the concentration of periodontal bacteria was recorded. Conclusion: Several findings still need to be confirmed with reference to the best suturing technique to reconstitute the nasal wing base, the real effectiveness of “surgery-first,” “maxilla-first,” and “mandible-first” approaches in patients with Class III malocclusion, the use of CAD/CAM and Laser, more studies should be conducted to evaluate quantitative and qualitative changes in other microorganisms following intermaxillary fixation.

19 January 2026 in Journal of Clinical Medicine
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Journal Article
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Maria Francesca SfondriniMaria Francesca Sfondrini
Maria Francesca Sfondrini
MPMaurizio Pascadopoli
Maurizio Pascadopoli
MNMaria Gloria Nardi
Maria Gloria Nardi
FCFilippo Cardarelli
Filippo Cardarelli
PBPaolo Zampetti Branchini
Paolo Zampetti Branchini
Andrea ScribanteAndrea Scribante
Andrea Scribante
Background/Objectives: This retrospective study evaluated and compared the cephalometric effects of an elastodontic bioactivator and conventional high-pull headgear in growing patients with hyperdivergent Class II malocclusion. Methods: Patients aged 7–11 years were divided into two groups according to the appliance used for the orthodontic treatment performed: elastodontic device (ED) and high-pull headgear (HPHD). Cephalometric measurements were recorded at baseline (T0) and after 18 months of treatment (T1). The data were subjected to statistical analysis, descriptive statistics were calculated, and an ANOVA test and post hoc Tukey test were performed (repeated measures correction was applied for intragroup comparisons). Linear regressions were conducted. Significance was predetermined as p < 0.05 for all the tests performed. Results: 40 patients were included, 20 belonging to the ED group and 20 to the HPHD group. Both groups showed a significant increase in SNB (p < 0.05), suggesting favorable mandibular positional changes. SNA and ANB did not show significant intra- or intergroup variations (p > 0.05). Regarding vertical skeletal parameters, no significant intra- or intergroup changes were observed at T0 and T1, indicating that both devices preserved vertical stability without worsening the hyperdivergent pattern. Dentoalveolar and soft-tissue effects were limited. Conclusions: Both ED and HPHD are effective in managing hyperdivergent Class II growing patients. The two appliances provide comparable improvements in mandibular positioning. Both devices seem to preserve vertical skeletal dimensions, avoiding further mandibular clockwise rotation. Both appliances are associated with minimal undesirable effects on the soft tissues.

2 March 2026 in European Journal of Translational Myology
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Journal Article
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MNMaria Gloria Nardi
Maria Gloria Nardi
Temporomandibular disorders (TMD) are a frequent source of non-dental orofacial pain, influenced by multifactorial biopsychosocial mechanisms. Surface electromyography (sEMG) of the masticatory muscles provides objective and minimally invasive metrics useful for characterizing neuromuscular alterations associated with TMD. The aim of this experimental study was to compare a group of patients with temporomandibular disorders (TMD) to a group of healthy controls using a standardized surface electromyography (sEMG) protocol, assessing measurements repeatability. Thirty participants (15 TMD patients and 15 healthy subjects) underwent two sEMG recordings separated by 7–14 days. Electromyographic activity of the masseter and anterior temporalis muscles was collected under both static (clenching) and dynamic (unilateral chewing) conditions. Intragroup findings indicate good intra-session and inter-session repeatability of the sEMG protocol in both healthy individuals and TMD patients. Inter-group analyses were performed to determine whether surface electromyography could discriminate healthy subjects from patients with temporomandibular disorders. The following indices showed statistically significant intergroup differences (p < 0.05) during the dynamic assessment: ellipse area, impact, number of chewing cycles, frequency and module index. Surface electromyography appears to be a potentially useful tool for monitoring muscle function over time both in healthy individuals and TMD patients; however, it did not demonstrate sufficient sensitivity to reliably differentiate healthy subjects from TMD patients. Further validation is required, including expanding the sample size, improving sample stratification and analyzing sEMG characteristics associated with different TMD subtypes.