M. Oliver Ahlers

Prof. Dr. M. Oliver Ahlers

University Medical Center Hamburg-Eppendorf, Hamburg, Germany
orcid
Director CMD Center Hamburg-Eppendorf and Senior Lecturer, U...

Research Focus & Metrics

Academic Career Length

25Years (2002-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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9 April 2020 in Journal of Oral Rehabilitation
Verified
Journal Article
Open access
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PWPeter Wetselaar
Peter Wetselaar
MWMiranda J.M. Wetselaar‐Glas
Miranda J.M. Wetselaar‐Glas
LKLukasz D. Katzer
Lukasz D. Katzer
MAM. Oliver Ahlers
M. Oliver Ahlers
Background: Tooth wear is a multifactorial condition, leading to the loss of dental hard tissues. Physiological tooth wear is a slow process that normally does not lead to any subjective symptoms. When the condition progresses, it can become pathological, and several signs and symptoms may occur. The Tooth Wear Evaluation System (TWES) was described to implement a systematic diagnostic and management approach. Recently, management guidelines were presented in a European Consensus Statement (ECS) as well.Objectives: To evaluate the TWES in practice and to integrate the principles described in the ECS in order to compose a renewed TWES 2.0 and a new taxonomy.Methods: The TWES and the recommendations of the ECS were used by dental clinicians, in order to test its applicability in practice.Results: Agreement was reached that the TWES 2.0 will use a stepwise approach, with a straightforward Tooth Wear Screening part and a more detailed Tooth Wear Status part. Also, the assessment of pathology from the ECS is incorporated in the TWES 2.0 (both classification and taxonomy).Conclusions: In the TWES 2.0 is described that tooth wear is pathological if moderate/severe/extreme tooth wear is present, in combination with one or several described signs and symptoms. Aetiology can be assessed by findings that indicate a chemical and/or a mechanical cause. The taxonomy may help to identify situations in which preventive (restorative) interventions in early stages of tooth wear can be indicated. The reliability and validity of the adapted parts must be proven.

1 January 2017 in Journal of Prosthodontic Research
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Journal Article
Closed access
ATAgnieszka Tarkowska
Agnieszka Tarkowska
LKLukasz Katzer
Lukasz Katzer
MAM. Oliver Ahlers
M. Oliver Ahlers
Previous research determined the relevance of masticatory performance with regard to nutritional status, cognitive functions, or stress management. In addition, the measurement of masticatory efficiency contributes to the evaluation of therapeutic successes within the stomatognathic system. However, the question remains unanswered as to what extent modern techniques are able to reproduce the subtle differences in masticatory efficiency within various patient groups. The purpose of this review is to provide an extensive summary of the evaluation of masticatory performance by means of a color-changeable chewing gum with regard to its clinical relevance and applicability. A general overview describing the various methods available for this task has already been published. This review focuses in depth on the research findings available on the technique of measuring masticatory performance by means of color-changeable chewing gum. Described are the mechanism and the differentiability of the color change and methods to evaluate the color changes. Subsequently, research on masticatory performance is conducted with regard to patient age groups, the impact of general diseases and the effect of prosthetic and surgical treatment. The studies indicate that color-changeable chewing gum is a valid and reliable method for the evaluation of masticatory function. Apart from other methods, in clinical practice this technique can enhance dental diagnostics as well as the assessment of therapy outcomes.

21 February 2020 in Journal of Oral Rehabilitation
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Journal Article
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BIBruno Imhoff
Bruno Imhoff
MAM. Oliver Ahlers
M. Oliver Ahlers
AHAlfons Hugger
Alfons Hugger
MLMatthias Lange
Matthias Lange
MSMarc Schmitter
Marc Schmitter
JTJens Christoph Türp
Jens Christoph Türp
Background: The diagnosis and management of patients suffering from occlusal dysesthesia (OD) remain a major challenge for dental practitioners and affected patients.Objectives: To present the results of a literature‐based expert consensus intended to promote better understanding of OD and to facilitate the identification and management of affected patients.Methods: In 2018, electronic literature searches were carried out in PubMed, Cochrane Library and Google Scholar as well as in the archives of relevant journals not listed in these databases. This approach was complemented by a careful assessment of the reference lists of the identified relevant papers. The articles were weighted by evidence level, followed by an evaluation of their contents and a discussion. The result represents an expert consensus.Results: Based on the contents of the 77 articles identified in the search, the current knowledge about clinical characteristics, epidemiology, aetiology, diagnostic process, differential diagnosis and management of OD is summarised.Conclusions: Occlusal dysesthesia exists independently of the occlusion. Instead, it is the result of maladaptive signal processing. The focus should be on patient education, counselling, defocusing, cognitive behavioural therapy, supportive drug therapy and certain non‐specific measures. Irreversible, specifically an exclusively dental treatment approach must be avoided.

Verified
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RKRobert Köhnke
Robert Köhnke
MAM. Oliver Ahlers
M. Oliver Ahlers
MBMoritz Alexander Birkelbach
Moritz Alexander Birkelbach
FEFlorian Ewald
Florian Ewald
MKMichael Krueger
Michael Krueger
RRRico Rutkowski
Rico Rutkowski
Temporomandibular joint osteoarthritis (TMJ-OA) is a chronic degenerative disease that is often characterized by progressive impairment of the temporomandibular functional unit. The aim of this randomized controlled animal trial was a comparative analysis regarding the chondroregenerative potency of intra-articular stem/stromal cell therapy. Four weeks after combined mechanical and biochemical osteoarthritis induction in 28 rabbits, therapy was initiated by a single intra-articular injection, randomized into the following groups: Group 1: AB Serum (ABS); Group 2: Hyaluronic acid (HA); Group 3: Mesenchymal stromal cells (STx.); Group 4: Mesenchymal stromal cells in hyaluronic acid (HA + STx.). After another 4 weeks, the animals were euthanized, followed by histological examination of the removed joints. The histological analysis showed a significant increase in cartilage thickness in the stromal cell treated groups (HA + STx. vs. ABS, p = 0.028; HA + ST.x vs. HA, p = 0.042; STx. vs. ABS, p = 0.036). Scanning electron microscopy detected a similar heterogeneity of mineralization and tissue porosity in the subchondral zone in all groups. The single intra-articular injection of a stem cell containing, GMP-compliant advanced therapy medicinal product for the treatment of iatrogen induced osteoarthritis of the temporomandibular joint shows a chondroregenerative effect.

1 January 2009
Verified
Journal Article
Closed access
MAM. Oliver Ahlers
M. Oliver Ahlers
GMG Mörig
G Mörig
UBU Blunck
U Blunck
JHJ Hajtó
J Hajtó
LPL Pröbster
L Pröbster
RFR Frankenberger
R Frankenberger

20 August 2019 in Journal of Oral Rehabilitation
Verified
Journal Article
Open access
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FLFrank Lobbezoo
Frank Lobbezoo
GAGhizlane Aarab
Ghizlane Aarab
MAM. Oliver Ahlers
M. Oliver Ahlers
LBLene Baad‐Hansen
Lene Baad‐Hansen
OBOlaf Bernhardt
Olaf Bernhardt
PSPeter Svensson
Peter Svensson
As yet, there are still no evidence‐based clinical diagnostic and management guidelines for ambulatory single‐channel EMG devices, like the BUTLER® GrindCare® (GrindCare), that are used in patients with sleep bruxism. Therefore, a consensus meeting was organised with GrindCare developers, researchers, and academic and non‐academic clinicians experienced with the use of ambulatory EMG devices. The aim of the meeting was to discuss and develop recommendations for clinical guidelines for GrindCare usage, based on the existing clinical and research experience of the consensus meeting's participants. As an important outcome of the consensus meeting, clinical guidelines were proposed in which an initial 2‐week baseline phase with the device in its inactive (non‐stimulus) mode for habituation and assessment of the number of jaw‐muscle activities is followed by a 4‐week active phase with contingent electrical stimuli suppressing the jaw‐muscle activities. As to avoid the commonly reported reduction in sensitivity to the stimuli, a 2‐week inactive phase is subsequently installed, followed by a repetition of active and inactive phases until a lasting reduction in the number of jaw‐muscle activities and/or associated complaints has been achieved. This proposal has the characteristics of a single‐patient clinical trial. From a research point of view, adoption of this approach by large numbers of GrindCare users creates a great opportunity to recruit relatively large numbers of study participants that follow the same protocol.