Paper based point-of-care (PoC) detection platforms applying lateral flow assays (LFAs) have gained paramount approval in the diagnostic domain as well as in environmental applications owing to their ease of utility, low cost, and rapid signal readout. It has centralized the aspect of self-evaluation exhibiting promising potential in the last global pandemic era of Covid-19 implementing rapid management of public health in remote areas. In this perspective, the present review is focused towards landscaping the current framework of LFAs along with integration of components and characteristics for improving the assay by pushing the detection limits. The review highlights the synergistic aspects of assay designing, sample enrichment strategies, novel nanomaterials-based signal transducers, and high-end analytical techniques that contribute significantly towards sensitivity and specificity enhancement. Various recent studies are discussed supporting the innovations in LFA systems that focus upon the accuracy and reliability of rapid PoC testing. The review also provides a comprehensive overview of all the possible difficulties in commercialization of LFAs subjecting its applicability to pathogen surveillance, water and food testing, disease diagnostics, as well as to agriculture and environmental issues.

We consider the effect of surface contamination, modelled by Marangoni elasticity with insoluble surfactant and surface viscosity, in promoting drift instabilities in spatially uniform standing Faraday waves. It is seen that contamination enhances drift instabilities that lead to various steadily propagating and (both standing and propagating) oscillatory patterns. In particular, steadily propagating waves appear to be quite robust, as a seminal experiment by Douady, Fauve & Thual (1989).

We consider the weakly nonlinear evolution of the Faraday waves produced in a vertically vibrated two-dimensional liquid layer, at small viscosity. It is seen that the surface wave evolves to a drifting standing wave, namely a wave that is standing in a moving reference frame. This wave is determined up to a spatial phase, whose calculation requires consideration of the associated mean flow. This is just the streaming flow generated in the boundary layer attached to the lower plate supporting the liquid. A system of equations is derived for the coupled slow evolution of the spatial phase and the streaming flow. These equations are numerically integrated to show that the simplest reflection symmetric steady state (the usual array of counter-rotating eddies below the surface wave) becomes unstable for realistic values of the parameters. The new states include limit cycles (the array of eddies oscillating laterally), drifted standing waves (patterns that are standing in a uniformly propagating reference frame) and some more complex attractors.