Laura Lorenzo-Gallego

Mrs. Laura Lorenzo-Gallego

University of Alcalá, Alcalá de Henares, Spain
orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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LDLara Díaz
Lara Díaz
LLLaura Lorenzo-Gallego
Laura Lorenzo-Gallego
HBHelena Romay Barrero
Helena Romay Barrero
Virginia Prieto GómezVirginia Prieto Gómez
Virginia Prieto Gómez
María Torres-LacombaMaría Torres-Lacomba
María Torres-Lacomba
BNBeatriz Navarro-Brazález
Beatriz Navarro-Brazález
Seventy percent of women with pelvic floor dysfunctions (PFDs) are estimated to present deficient consciousness of their pelvic floor muscles (PFMs) and poor ability to contract them. Improving the proprioception of PFMs, defined as the capacity to know the status and position of each body part, and adequately contracting them could be a protective factor to prevent the appearance of PFDs in the general female population. This study aimed to identify the effectiveness of educational interventions and verbal instructions on how to contract and exercise the PFMs to improve the proprioception of the PFMs in women. A systematic search of studies published in the last 20 years until March 2022 was conducted in the PubMed, Cochrane Library, Web of Science, Scopus, PEDro, Lilacs, and Dialnet databases. A meta-analysis could not be performed due to the heterogeneity in the types of studies and included populations. This review followed the PRISMA guidelines for the design, search, and reporting of studies. The methodological quality was analysed via the PEDro and the Newcastle–Ottawa scales in the case of randomised clinical trials and non-randomised studies, respectively, while the quality of evidence was determined using the SIGN grading system for evidence-based guidelines. Descriptive and experimental studies published in English, Spanish, or Portuguese that evaluated the contractile capability of the PFMs in healthy women or women without a previous diagnosis of PFD were included. Seven articles that included a total of 2507 women were found, three of which were clinical trials with PEDro scores between 5 and 9 points out of 10 and four of which were non-randomised studies with NOS scores between 6 and 8 points out of 10. The outcomes were measured through vaginal palpation, visual observation, questionnaires for PFD symptoms, and self-perception reports. This review discriminated between two types of intervention, educational programmes and verbal instructions, and evaluated the changes observed in PFM strength and knowledgeability and the symptoms of PFDs. The findings showed that educational interventions and verbal instructions improve the proprioception of PFMs in women of all ages that are healthy or without a previous diagnosis of PFDs as well as their knowledge about the pelvic floor, healthy lifestyle habits, and symptoms that are potentially indicative of PFDs. Further high-quality randomised clinical trials are warranted to draw definitive conclusions about the effectiveness of educational interventions to improve the proprioception of the PFMs in women considered healthy or with mild symptoms that may be indicative of PFDs.

LLLaura Lorenzo-Gallego
Laura Lorenzo-Gallego
BABeatriz Arranz-Martín
Beatriz Arranz-Martín
HBHelena Romay Barrero
Helena Romay Barrero
Virginia Prieto GómezVirginia Prieto Gómez
Virginia Prieto Gómez
ELEnrique Lluch
Enrique Lluch
María Torres-LacombaMaría Torres-Lacomba
María Torres-Lacomba
This study aimed to investigate changes in the pain sensory profile of women with breast cancer. Five women with unilateral breast cancer were enrolled. Participants were assessed with direct (quantitative sensory testing, QST) and indirect measures of pain sensitization (self-reported central sensitization inventory, CSI) at baseline (before surgery), 1 week after surgery, and at 1, 6, 9, and 12 months post-surgery. In the event of pain occurrence, the Leeds Assessment of Neuropathic Symptoms and Signs was also used. Nociceptive pain was the predominant pain mechanism in the postoperative period, while an increase in sensitization predominated one year after breast cancer surgery, especially in those participants who had received more treatment procedures. The participants who received more therapies for breast cancer experienced persistent pain and a higher level of sensitization. An assessment protocol including direct measurements (QST) and indirect measurement (self-reported CSI) allows for detecting changes in pain sensitivity, which can be useful for characterizing and/or predicting pain before, during, and up to one year following surgical interventions for breast cancer.

23 February 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
BNBeatriz Navarro-Brazález
Beatriz Navarro-Brazález
LLLaura Lorenzo-Gallego
Laura Lorenzo-Gallego
PMPaula Rangel de la Mata
Paula Rangel de la Mata
María Torres-LacombaMaría Torres-Lacomba
María Torres-Lacomba
FPfernando vergara pérez
fernando vergara pérez
NMNuria Izquierdo Mendez
Nuria Izquierdo Mendez
Background/Objectives: Approximately 30% of women experience pelvic pain one year after vaginal delivery, and this increases to 50% during vaginal intercourse. Multimodal physiotherapy is the first-line treatment for myofascial pain of the pelvic floor muscles (PFM), often incorporating emerging technologies like radiofrequency, despite limited evidence supporting its use. The RASDOP study aims to (i) evaluate the effectiveness of multimodal physiotherapy combining therapeutic education, PFM training, and myofascial pain syndrome (MPS) management with or without radiofrequency, in reducing pain and improving sexual function postpartum; and (ii) explore the barriers and facilitators influencing adherence and perceived self-efficacy towards physiotherapy treatment in women with postpartum pelvic pain. Methods: This study employs a randomized clinical trial with a blinded examiner and two parallel groups, followed by a qualitative phenomenological study. A total of 124 postpartum women with pelvic pain (≥4 cm on the visual analogue scale) will be randomized into two groups: a multimodal physiotherapy group (therapeutic education, MPS treatment, and PFM training) and a radiofrequency + multimodal physiotherapy group (same treatment with additional non-ablative radiofrequency). Both groups will receive 12 supervised individual sessions. Assessments will be conducted pre- and post-intervention, and at 3-, 6-, and 12-month stages post-treatment. Primary outcomes include pain intensity and sexual function, while secondary outcomes involve PFM tone, strength, MPS presence, levator ani length, and distress caused by pelvic floor dysfunction. The qualitative study will utilize semi-structured interviews and focus groups analyzed thematically. Results: Radiofrequency is expected to enhance pain relief, sexual function, and PFM relaxation. Insights into adherence and barriers will aid in personalizing physiotherapy interventions. Conclusions: The RASDOP study will provide evidence on the safety and efficacy of radiofrequency in postpartum pelvic pain treatment and shed light on women’s experiences to improve therapeutic outcomes.

27 November 2025 in BMJ Open
Verified
Journal Article
Open access
María Torres-LacombaMaría Torres-Lacomba
María Torres-Lacomba
CHCarmen María Hernández-Iglesias
Carmen María Hernández-Iglesias
CVCristina del Valle-Rubido
Cristina del Valle-Rubido
BNBeatriz Navarro-Brazález
Beatriz Navarro-Brazález
PMPaula Rangel-De la Mata
Paula Rangel-De la Mata
JFJesús Lázaro-Carrasco de la Fuente
Jesús Lázaro-Carrasco de la Fuente
Introduction: Genitourinary syndrome of menopause (GSM) is a prevalent condition among breast cancer survivors, often exacerbated by oncological treatments. Hormonal therapies are typically contraindicated in this population, necessitating effective non-hormonal interventions. Methods and analysis: This randomised controlled trial aims to compare the effectiveness and cost-effectiveness of multimodal pelvic floor physiotherapy—comprising pelvic floor muscle training, non-ablative radiofrequency, therapeutic pelvic health education and the use of vaginal moisturisers—versus fractional CO ₂ laser therapy combined with vaginal moisturisers in alleviating GSM symptoms in breast cancer survivors. Participants will be randomly assigned to one of the two intervention groups. Primary outcomes include measures of sexual function (assessed by the Female Sexual Function Index), subjective pelvic perineal pain intensity (measured with a 100 mm Visual Analogue Scale) and health-related quality of life (assessed by the Functional Assessment of Cancer Therapy-Breast), assessed at baseline, post-intervention and at 3, 6 and 12 months of follow-up. Statistical analyses will be conducted to evaluate the clinical efficacy and cost-effectiveness of the interventions. Ethics and dissemination: The study protocol has been approved by the Ethics and Health Research Committee of the University of Alcalá (Reference: CEIP/2024/1/012). All participants will provide informed consent prior to inclusion in the study. Findings will be disseminated through peer-reviewed journals and conference presentations, and by engaging with patient associations and survivor groups through tailored materials. Trial registration number: NCT06721936 .

19 September 2026 in Current Oncology
Verified
Journal Article
Open access
PDF file
LLLaura Lorenzo-Gallego
Laura Lorenzo-Gallego
NDNicola S Diciolla
Nicola S Diciolla
FRFernando Ramos
Fernando Ramos
Virginia Prieto GómezVirginia Prieto Gómez
Virginia Prieto Gómez
CGCouso Aldina González
Couso Aldina González
María Torres-LacombaMaría Torres-Lacomba
María Torres-Lacomba
Background: Breast cancer survivors frequently experience persistent sensory, psychosocial, and functional sequelae that may not be captured by pain measures alone. Understanding recovery trajectories throughout treatment and survivorship may help identify women at risk of long-term recovery-related difficulties. Objective: To investigate sensory, psychosocial, functional, and quality-of-life trajectories throughout breast cancer treatment. Methods: This prospective longitudinal study included women undergoing unilateral breast cancer surgery assessed at six time points before and after surgery, including before and after adjuvant treatments when applicable. Outcomes included sensory function, pain, upper-limb function, psychosocial variables, and quality of life. Results: Seventy-two women (57 ± 11 years) were included. Despite stable pain intensity and self-reported sensitization symptoms, fear of movement increased (TSK-11: MD [95%CI] = +9[0;22]), quality of life deteriorated (FACT-B: 3–12 month MD [95%CI] = −10[−19;−1]), and upper-limb function initially worsened before partially recovering. Objective sensory alterations suggested dynamic changes in somatosensory processing but were not consistently accompanied by greater pain intensity or self-reported sensitization symptoms. Conclusions: Recovery after breast cancer treatment is multidimensional and cannot be adequately reflected by pain intensity alone. Multidimensional assessment may help identify women at risk of persistent recovery-related difficulties and support personalized survivorship care.

17 August 2026 in Fisioterapia
Verified
Journal Article
Closed access
LLLaura Lorenzo-Gallego
Laura Lorenzo-Gallego
PSP. Segovia-Gómez
P. Segovia-Gómez
VPV. Prieto-Gómez
V. Prieto-Gómez
JBJ. Bailón-Cerezo
J. Bailón-Cerezo
MTM. Torres-Lacomba
M. Torres-Lacomba