Background and Objective.The purpose of this study was to highlight the clinical performance of platelet-rich plasma (PRP) used as an adjunctive tool for regeneration in infrabony periodontal defects using different biomaterials or performing different surgical flap approaches. Comparative evaluation of main clinical outcomes as probing pocket depth reduction, clinical attachment gain, and recession reduction with and without the use of PRP has been analysed.Materials and Methods. According to the focused question, an electronic and hand searching has been performed up to December 2016. From a batch of 73 articles, the selection strategy and Jadad quality assessment led us to include 15 studies for the meta-analysis.Results.Despite the high heterogeneity found and the lack of complete data regarding the selected clinical outcomes, a comparative analysis has been possible by the categorization of used biomaterials and surgical flap approaches. This method led us to observe the best performance of grafts with the use of adjunctive PRP in CAL gain and PPD reduction. No difference has been outlined with a specific surgical flap.Conclusions.Although PRP is considered a cheap and patient’s derived growth factor, the not conclusive data reported would suggest that its use in addition to bone substitutes could be of some clinical benefit in the regenerative treatment of infrabony defects.Clinical Relevance. This systematic review was intended to sort out the huge controversial debate in the field about the possible use of PRP in regenerative surgery in infrabony defect. The clinical relevance of using blood-borne growth factors to conventional procedures is effective as these could determine a better performance and outcomes despite the surgical approach adopted and limit the use of additional biomaterials for the blood clot stabilization.

Objective: The aim of the study was to analyze the distribution of color parameters, lightness (L*), chroma (C), hue (H), a* and b*, in the intercanine sector in maxilla. Material and Methods: Patients' tooth color measurements were performed using an intraoral spectrophotometer VITA Easyshade^® (VITA Zahnfabrik H. Rauter GmbH and Co. KG, Bad Sackingen, Germany). The measurements were made in 255 subjects in the intercanine sector in maxilla. Results: The mean values for the group of 255 subjects were as follows: L*, a*, b*, C, and H as 81.6, 0.67, 21.6, 21.7, and 92.7, respectively. For F=206.27 and P < 0.001 between L*, a*, b*, C, H, and central incisor/lateral incisor/canines, there were statistically significant differences. Conclusion: With the statistical analysis, it was determined that there are significant color differences between the teeth of the intercanine sector, which differences are clinically significant also.

OBJECTIVES: During the treatment of chronic apical periodontitis and pulp necrosis the main role is to irrigate the root canal.AIM: The aim of this in vivo study was to irrigate with 0.9% NaCl (Natrium Chloride), 2.5 % NaOCl (Sodium Hypochlorite Solution, Sigma Aldrich - Germany) and 2% CHX (Chlorhexidine Digluconate Solution, Sigma Aldrich - Spain) combined with Gaseous Ozone (Prozone WH, Austria).MATERIAL AND METHODS: This study was realised in the University Dentistry Clinical Centre of Kosovo (UDCCK), respectively in the Department of Endodontic and Dental Pathology, Dental Branch, Faculty of Medicine, Prishtina, Kosovo. The 40 subjects involved in this study belonged to both genders, in age between 15 -65 years. The sample selection was randomised. The retroalveolar radiography for each patient was taken in the suspected tooth. As a therapeutic plan the authors decided to disinfect the root canal with the irrigants, as follows: 2.5 % NaOCl, 2 % CHX and gaseous ozone.RESULTS: The statistical analyses were based on Kruskal - Vallis test, X - test, DF = 3, r < 0.01. In the isolated average number of the aerobe and anaerobe bacteria colonies, when gaseous ozone was used, there was the significant statistical difference.CONCLUSIONS: When gaseous ozone was combined with irrigants 0.9%, 2.5 % NaOCl and 2% CHX, it was concluded that the number of colonies of aerobic and anaerobic bacteria was reduced.

Objective. The aim of this study was to evaluate sensibility threshold for interocclusal thickness in experienced and nonexperienced denture wearers after the insertion of new complete dentures.Materials and Methods. A total of 88 patients with complete dentures have participated in this study. The research was divided into two experimental groups, compared with the previous experience prosthetic dental treatment. The sensibility threshold for interocclusal thickness was measured with metal foil with 8 μm thickness and width of 8 mm, placed between the upper and lower incisor region. Statistical analysis was performed using standard software package BMDP (biomedical statistical package).Results. Results suggest that time of measurement affects the average values of the sensibility threshold for interocclusal thickness (F= 242.68,p= 0.0000). Gender appeared to be a significant factor when it interacted with time measurement resulting in differences in sensibility threshold for interocclusal thickness (gender:F= 9.84,p= 0.018;F= 4.83,p= 0.0003).Conclusion. The sensibility threshold for interocclusal thickness was the most important functional adaptation in patient with complete dentures. A unique trait of this indicator is the progressive reduction of initial values and a tendency to reestablish the stationary state in the fifteenth week after dentures is taken off.

BACKGROUND: There are a lot of factors influencing the efficiency of mastication; therefore there are also a lot of methods for testing this efficiency.OBJECTIVE: The study aimed to test the efficiency of mastication and evaluate it in the function of time, based on previous experience with the complete dentures.METHODS: A total of 88 patients (42 female, 46 male, mean age 52.2, SD = 5.76), complete dentures wearers, participated in this study. Masticatory functions were investigated by using the method of electromyography (EMG), analyzing electromyomasticatiogram. For testing the masticator efficiency, the further parameters of the masticatiogram were used: duration of the Standard Masticatory Task (SMT) (t), number of the masticatory cycles within the masticator arch (F) and maximal amplitude within the masticatory arch (F). All data were statistically analysed by using standard software package BMDP (bio-medical Statistical package). Parametric data have been tested using One Way Repeated Measurement of ANOVA test.RESULTS: The changes of the relation A/t are evident in different time intervals in both measured sides: F-DS-time of the measurement = 34.86, P = 0.0000; F-NDS- time of the measurement = 26.1, P = 0.0000. There are also differences of the masticatory index A/t between sexes in both, dominant and non-dominant side: F-DS-gender = 237.05, P = 0.0000; F-NDS-gender = 12.90, P = 0.004. Masticatory index (A/F) varies in time, from first to the sixth measurement in both sides: F-DS-time of the measurement = 32.36, P = 0.0000; F-NDS-time of the measurement = 30.53, P = 0.0000. The interaction of the time and gender was also important: F-DS-interaction = 6.95, P = 0.0000; F-NDS-interaction = 14.9, P = 0.0000.CONCLUSION: Masticator indexes are A/F, and A/t are a very important indicator of the masticatory efficiency and the level of the functional adaptation on complete dentures. Both masticator indexes show the same dynamics (reaching the stationary condition after the 15th week after getting new dentures). After the observing period, all examinee express the same degree of masticator efficiency known as functional adaptation. Patients with previous experience with complete dentures reach faster the stationary condition, compared with those non-experienced.

AIM: The study aimed to analyse differences in colourimetric parameters L*a*b*, depended on age.MATERIAL AND METHODS: In this study were included 255 subjects with age interval from 20 to 49 years. The subjects were divided into three groups, as follows: in the younger group were 20 to 29 years of age, those in the middle group 30 to 39 years and older group 40 to 49 years. The overall number of analysed teeth in the intercanine sector of the maxilla was 2295. The colour of the teeth was measured using the spectrophotometer VITA Easyshade.RESULTS: The results for differences in the colourimetric parameters in relation with age were tested with Pearson Chi-square (c2). For c 2 = 572, 87 and df = 124 there was a statistical significant difference between the ages P < 0.001.CONCLUSION: In this study, it was concluded that the parameter L* - Lightness was decreasing when age increased. In the age group, 20 to 29 years L* was 83.2, whereas in the older group of this investigation; 40 to 49 years was 79.4. In the youngest group, the parameter a* was - 0.7, whereas with increasing of age this parameter was -0.5. The values for parameter b* from the youngest to the older group were from 21.7 to 23.9.