High‐speed plasma jets downstream of Earth's bow shock are high velocity streams associated with a variety of shock and magnetospheric phenomena. In this work, using the Magnetosphere Multiscale mission, we study the properties of a jet found downstream of the Quasi‐parallel bow shock using high‐resolution (burst) data. By doing so, we demonstrate how the jet is an inherently kinetic structure described by highly variable velocity distributions. The observed distributions show the presence of two plasma population, a cold/fast jet and a hotter/slower background population. We derive partial moments for the jet population to isolate its properties. The resulting partial moments appear different from the full ones which are typically used in similar studies. These discrepancies show how jets are more similar to upstream solar wind beams compared to what was previously believed. Finally, we explore the consequences of our results and methodology regarding the characterization, origin, and evolution of jets.
1 May 2019 in Applied Immunohistochemistry & Molecular Morphology
High-quality patient samples are required for reliable immunohistochemistry test outcomes that provide a significant benefit for patient care. Among the preanalytic variables in tissue handling, tissue thickness is thought to be easily controlled; however, whether the thickness of the tissue effects the staining intensity for antibody immunohistochemistry has not been quantitatively demonstrated. To investigate, we cut multiblock tissue sections of tonsil, liver, and kidney at 2, 4, 6, and 8 μm thicknesses. Interferometry measurements of the sectioned paraffin showed a <1 μm variation within a preset microtome thickness. Sections were then immunostained with antibodies targeting different cellular localizations; Ki-67 and BCL6 (nuclear), CD7 (membranous), and cytokeratin (cytoplasmic). A pathologist annotated regions of interest for each marker and performed brightfield and whole-slide visual scoring. Then a pixel-wise processing algorithm determined intensity of each pixel in these regions of interest and binned them into predetermined 0, 1+, 2+, or 3+ intensities. Visual scores from brightfield and whole-slide images were highly correlated to the percentage of pixels in each intensity bin. A stepwise increase was observed in pathologist scores and algorithmically defined percentage of pixels in each bin with increasing thickness demonstrating that changes in preset section thickness impacts staining intensity. The use of tissue thickness outside vendors’ recommendations might change the intensity including the proportion of positive and negative cells and eventually the overall diagnosis outcome. Therefore, we recommend that tissue be consistently cut within the middle of thickness range specified by the assay manufacturer.
Collisionless shock waves, found in supernova remnants, interstellar, stellar, and planetary environments, and laboratories, are one of nature’s most powerful particle accelerators. This study combines in situ satellite measurements with recent theoretical developments to establish a reinforced shock acceleration model for relativistic electrons. Our model incorporates transient structures, wave-particle interactions, and variable stellar wind conditions, operating collectively in a multiscale set of processes. We show that the electron injection threshold is on the order of suprathermal range, obtainable through multiple different phenomena abundant in various plasma environments. Our analysis demonstrates that a typical shock can consistently accelerate electrons into very high (relativistic) energy ranges, refining our comprehension of shock acceleration while providing insight on the origin of electron cosmic rays.
Energetic electrons have been frequently observed during magnetic reconnection in the magnetotail. The acceleration process of the energetic electrons is not fully understood. In this paper, we select for a detailed study a case of energetic electron acceleration from the earlier reported interval of turbulent magnetic reconnection in Earth’s magnetotail observed by the Magnetospheric Multiscale mission. We use the first-order Taylor expansion method to reconstruct the magnetic topology of electron acceleration sites from the data. We find that the energetic electron fluxes increase inside the flux rope forming in front of the magnetic pileup region. We show that the energetic electrons are produced by a two-step process where two different acceleration mechanisms are successively operating outside and inside the flux rope. First, the thermal electrons are energized in the field-aligned direction inside the magnetic pileup region owing to the Fermi mechanism forming a cigar-like distribution. Second, those energized electrons are further accelerated predominately antiparallel to the magnetic field direction by a parallel electric field inside the flux rope. Our findings provide information for a better understanding of the generation of energetic electrons during turbulent reconnection process.
We use the Magnetospheric Multiscale mission (MMS) to study electron acceleration at Earth's quasi‐perpendicular bow shock to address the long‐standing electron injection problem. The observations are compared to the predictions of the stochastic shock drift acceleration (SSDA) theory. Recent studies based on SSDA predict electron distribution being a power law with a cutoff energy that scales with upstream parameters. This scaling law has been successfully tested for a single Earth's bow shock crossing by MMS. Here we extend this study and test the prediction of the scaling law for seven MMS Earth's bow shock crossings with different upstream parameters. A goodness‐of‐fit test shows good agreement between observations and SSDA theoretical predictions, thus supporting SSDA as one of the most promising candidates for solving the electron injection problem.
We use the Magnetospheric Multiscale mission to observe a bi‐directional electron acceleration event in the electron foreshock upstream of Earth's quasi‐perpendicular collisionless bow shock. The acceleration region is associated with a decrease in wave activity, inconsistent with common electron acceleration mechanisms such as Diffusive Shock Acceleration and Stochastic Shock Drift Acceleration. We propose a two‐step acceleration process where an electron field‐aligned beam acts as a seed population further accelerated by a shrinking magnetic bottle process, with the shock acting as the magnetic mirror(s).