A techno-economic analysis has been used to evaluate three processes for hydrogen production from advanced steam reforming (SR) of bio-oil, as an alternative route to hydrogen with BECCS: conventional steam reforming (C-SR), C-SR with CO₂ capture (C-SR-CCS), and sorption-enhanced chemical looping (SE-CLSR). The impacts of feed molar steam to carbon ratio (S/C), temperature, pressure, the use of hydrodesulphurisation pretreatment, and plant production capacity were examined in an economic evaluation and direct CO₂ emissions analysis. Bio-oil C-SR-CC or SE-CLSR may be feasible routes to hydrogen production, with potential to provide negative emissions. SE-CLSR can improve process thermal efficiency compared to C-SR-CCS. At the feed molar steam to carbon ratio (S/C) of 2, the levelised cost of hydrogen (USD 3.8 to 4.6 per kg) and cost of carbon avoided are less than those of a C-SR process with amine-based CCS. However, at higher S/C ratios, SE-CLSR does not have a strong economic advantage, and there is a need to better understand the viability of operating SE-CLSR of bio-oil at high temperatures (>850 °C) with a low S/C ratio (e.g., 2), and whether the SE-CLSR cycle can sustain low carbon deposition levels over a long operating period.