The identification and prognosis of the potential for developing Cardiovascular Diseases (CVD) in healthy individuals is a vital aspect of disease management. Accessing the comprehensive health data on CVD currently available within hospital databases holds significant potential for the early detection and diagnosis of CVD, thereby positively impacting disease outcomes. Therefore, the incorporation of machine learning methods holds significant promise in the advancement of clinical practice for the management of Cardiovascular Diseases (CVDs). By providing a means to develop evidence-based clinical guidelines and management algorithms, these techniques can eliminate the need for costly and extensive clinical and laboratory investigations, reducing the associated financial burden on patients and the healthcare system. In order to optimize early prediction and intervention for CVDs, this study proposes the development of novel, robust, effective, and efficient machine learning algorithms, specifically designed for the automatic selection of key features and the detection of early-stage heart disease. The proposed Catboost model yields an F1-score of about 92.3% and an average accuracy of 90.94%. Therefore, Compared to many other existing state-of-art approaches, it successfully achieved and maximized classification performance with higher percentages of accuracy and precision.

Alzheimer’s disease (AD) is a chronic disease that affects the elderly. There are many different types of dementia, but Alzheimer’s disease is one of the leading causes of death. AD is a chronic brain disorder that leads to problems with language, disorientation, mood swings, bodily functions, memory loss, cognitive decline, mood or personality changes, and ultimately death due to dementia. Unfortunately, no cure has yet been developed for it, and it has no known causes. Clinically, imaging tools can aid in the diagnosis, and deep learning has recently emerged as an important component of these tools. Deep learning requires little or no image preprocessing and can infer an optimal data representation from raw images without prior feature selection. As a result, they produce a more objective and less biased process. The performance of a convolutional neural network (CNN) is primarily affected by the hyperparameters chosen and the dataset used. A deep learning model for classifying Alzheimer’s patients has been developed using transfer learning and optimized by Gorilla Troops for early diagnosis. This study proposes the A${}^3$C-TL-GTO framework for MRI image classification and AD detection. The A${}^3$C-TL-GTO is an empirical quantitative framework for accurate and automatic AD classification, developed and evaluated with the Alzheimer’s Dataset (four classes of images) and the Alzheimer’s Disease Neuroimaging Initiative (ADNI). The proposed framework reduces the bias and variability of preprocessing steps and hyperparameters optimization to the classifier model and dataset used. Our strategy, evaluated on MRIs, is easily adaptable to other imaging methods. According to our findings, the proposed framework was an excellent instrument for this task, with a significant potential advantage for patient care. The ADNI dataset, an online dataset on Alzheimer’s disease, was used to obtain magnetic resonance imaging (MR) brain images. The experimental results demonstrate that the proposed framework achieves 96.65% accuracy for the Alzheimer’s Dataset and 96.25% accuracy for the ADNI dataset. Moreover, a better performance in terms of accuracy is demonstrated over other state-of-the-art approaches.

Many people worldwide suffer from mental illnesses such as major depressive disorder (MDD), which affect their thoughts, behavior, and quality of life. Suicide is regarded as the second leading cause of death among teenagers when treatment is not received. Twitter is a platform for expressing their emotions and thoughts about many subjects. Many studies, including this one, suggest using social media data to track depression and other mental illnesses. Even though Arabic is widely spoken and has a complex syntax, depressive detection methods have not been applied to the language. The Arabic tweets dataset should be scraped and annotated first. Then, a complete framework for categorizing tweet inputs into two classes (such as Normal or Suicide) is suggested in this study. The article also proposes an Arabic tweet preprocessing algorithm that contrasts lemmatization, stemming, and various lexical analysis methods. Experiments are conducted using Twitter data scraped from the Internet. Five different annotators have annotated the data. Performance metrics are reported on the suggested dataset using the latest Bidirectional Encoder Representations from Transformers (BERT) and Universal Sentence Encoder (USE) models. The measured performance metrics are balanced accuracy, specificity, F1-score, IoU, ROC, Youden Index, NPV, and weighted sum metric (WSM). Regarding USE models, the best-weighted sum metric (WSM) is 80.2%, and with regards to Arabic BERT models, the best WSM is 95.26%.

Sarcoidosis is frequently misdiagnosed as tuberculosis (TB) and consequently mistreated due to inherent limitations in radiological presentations. Clinically, to distinguish sarcoidosis from TB, physicians usually employ biopsy tissue diagnosis and blood tests; this approach is painful for patients, time-consuming, expensive, and relies on techniques prone to human error. This study proposes a computer-aided diagnosis method to address these issues. This method examines seven EfficientNet designs that were fine-tuned and compared for their abilities to categorize X-ray images into three categories: normal, TB-infected, and sarcoidosis-infected. Furthermore, the effects of stain normalization on performance were investigated using Reinhard’s and Macenko’s conventional stain normalization procedures. This procedure aids in improving diagnostic efficiency and accuracy while cutting diagnostic costs. A database of 231 sarcoidosis-infected, 563 TB-infected, and 1010 normal chest X-ray images was created using public databases and information from several national hospitals. The EfficientNet-B4 model attained accuracy, sensitivity, and precision rates of 98.56%, 98.36%, and 98.67%, respectively, when the training X-ray images were normalized by the Reinhard stain approach, and 97.21%, 96.9%, and 97.11%, respectively, when normalized by Macenko’s approach. Results demonstrate that Reinhard stain normalization can improve the performance of EfficientNet -B4 X-ray image classification. The proposed framework for identifying pulmonary sarcoidosis may prove valuable in clinical use.